• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

ZP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS641374

The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural… More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ZP1, Polyclonal Antibody
Full Product Name
ZP1, CT (ZP1, Zona pellucida sperm-binding protein 1, Zona pellucida glycoprotein 1, Processed zona pellucida sperm-binding protein 1)
Product Gene Name
Product Synonym Names
Anti -ZP1, CT (ZP1, Zona pellucida sperm-binding protein 1, Zona pellucida glycoprotein 1, Processed zona pellucida sperm-binding protein 1)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
70,049 Da
Chromosome Location
Chromosome: 11; NC_000011.9 (60635015..60643164). Location: 11q12.2
OMIM
195000
3D Structure
ModBase 3D Structure for P60852
Immunogen
ZP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 535-565 amino acids from the C-terminal region of human ZP1.
Applications Tested/Suitable for anti-ZP1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-ZP1 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-ZP1 antibody

ZP1 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ZP1 antibody detected the ZP1 protein (arrow).
Rabbit Anti-ZP1 Polyclonal Antibody – Cat# MBS641374

Other Notes

Small volumes of anti-ZP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZP1 purchase

MBS641374 is an antibody targeting ZP1. Also known as ZP1, CT (ZP1, Zona pellucida sperm-binding protein 1, Zona pellucida glycoprotein 1, Processed zona pellucida sperm-binding protein 1). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ZP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
zona pellucida sperm-binding protein 1
NCBI Official Synonym Full Names
zona pellucida glycoprotein 1 (sperm receptor)
NCBI Official Symbol
ZP1
UniProt Protein Name
Zona pellucida sperm-binding protein 1
UniProt Synonym Protein Names
Zona pellucida glycoprotein 1
UniProt Gene Name
ZP1
UniProt Synonym Gene Names
Zp-1
UniProt Entry Name
ZP1_HUMAN
NCBI Protein Information
zona pellucida sperm-binding protein 1; zp-1; zona pellucida protein 1

NCBI Summary for ZP1

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene ensures the structural integrity of the zona pellucida. Mutations in this gene are a cause of oocyte maturation defect and infertility. [provided by RefSeq, May 2014]
Show more

UniProt Comments for ZP1

ZP1: The mammalian zona pellucida, which mediates species- specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural integrity of the zona pellucida. Belongs to the ZP domain family. ZPB subfamily.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q12.2

Cellular Component: Golgi apparatus; proteinaceous extracellular matrix; extracellular region; plasma membrane; integral to membrane; secretory granule

Biological Process: binding of sperm to zona pellucida; single fertilization; multicellular organism reproduction

Disease: Oocyte Maturation Defect
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000