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PLB1 Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS641392

Membrane-associated phospholipase. Exhibits a calcium-independent broad substrate specificity including phospholipase A2/lysophospholipase activity. Preferential hydrolysis at the sn-2 position of diacylphospholipids and diacyglycerol, whereas it shows no… More details

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Testing Data View PDF
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Product Overview

Online Datasheet in PDF
Product Name
PLB1, Polyclonal Antibody
Full Product Name
PLB1 (Phospholipase B1, Membrane-associated, Phospholipase B, hPLB, Phospholipase B/Lipase, PLB/LIP, PLB, FLJ30866)
Product Gene Name
anti-PLB1 antibody
Product Synonym Names
Anti -PLB1 (Phospholipase B1, Membrane-associated, Phospholipase B, hPLB, Phospholipase B/Lipase, PLB/LIP, PLB, FLJ30866)
Immunogen Sequence
MEPAGEKDEP LSVKHGRPMK CPSQESPYLF SYRNSNYLTR LQKPQDKLEV REGAEIRCPD KDPSDTVPTS VHRLKPADIN VIGALGDSLT AGNGAGSTPG NVLDVLTQYR GLSWSVGGDE NIGTVTTLAN ILREFNPSLK GFSVGTGKET SPNAFLNQAV AGGRAEDLPV QARRLVDLMK NDTRIHFQED WKIITLFIGG NDLCDFCNDL VHYSPQNFTD NIGKALDILH AEVPRAFVNL VTVLEIVNLR ELYQEKKVYC PRMILRSLCP CVLKFDDNST ELATLIEFNK KFQEKTHQLI ESGRYDTRED FTVVVQPFFE NVDMPKTSEG LPDNSFFAPD CFHFSSKSHS RAASALWNNM LEPVGQKTTR HKFENKINIT CPNQVQPFLR TYKNSMQGHG TWLPCRDRAP SALHPTSVHA LRPADIQVVA ALGDSLTAGN GIGSKPDDLP DVTTQYRGLS YRESKPGFLS DSWVSKSNRK CTRKAPNP
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human PLB1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
163,081 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (28718938..28866654). Location: 2p23.2
OMIM
610179
3D Structure
ModBase 3D Structure for Q6P1J6
Immunogen
Full length human PLB1, aa1-488 (AAH65041).

Product Categories/Family for anti-PLB1 antibody

Antibodies; Abs to Enzymes; Phospholipase
Applications Tested/Suitable for anti-PLB1 antibody
Western Blot (WB)
Application Notes for anti-PLB1 antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-PLB1 antibody

PLB1 polyclonal antibody. Western Blot analysis of PLB1 expression in human colon.
Mouse Anti-PLB1 Polyclonal Antibody – Cat# MBS641392

Western Blot (WB) of anti-PLB1 antibody

Western Blot analysis of PLB1 expression in transfected 293T cell line by PLB1 polyclonal antibody. Lane 1: PLB1 transfected lysate (53.68kD). Lane 2: Non-transfected lysate.
Mouse Anti-PLB1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS641392

Other Notes

Small volumes of anti-PLB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLB1 purchase

MBS641392 is an antibody targeting PLB1. Also known as PLB1 (Phospholipase B1, Membrane-associated, Phospholipase B, hPLB, Phospholipase B/Lipase, PLB/LIP, PLB, FLJ30866). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PLB1. It may not necessarily be applicable to this product.

NCBI GI #
40674028
NCBI GeneID
151056
NCBI Accession #
AAH65041.1
UniProt Primary Accession #
Q6P1J6
UniProt Secondary Accession #
Q53S03; Q8IUP7; Q96DP9; A8KAX2
UniProt Related Accession #
Q6P1J6
NCBI Official Full Name
PLB1 protein
NCBI Official Synonym Full Names
phospholipase B1
NCBI Official Symbol
PLB1
NCBI Official Synonym Symbols
PLB; hPLB; PLB/LIP
UniProt Protein Name
Phospholipase B1, membrane-associated
UniProt Synonym Protein Names
Phospholipase B/lipase
Protein Family
Lysophospholipase
UniProt Gene Name
PLB1
UniProt Synonym Gene Names
PLB; Phospholipase B; hPLB; PLB/LIP
UniProt Entry Name
PLB1_HUMAN
NCBI Protein Information
phospholipase B1, membrane-associated; phospholipase A2; lysophospholipase; phospholipase B/lipase

UniProt Comments for PLB1

PLB1: Membrane-associated phospholipase. Exhibits a calcium- independent broad substrate specificity including phospholipase A2/lysophospholipase activity. Preferential hydrolysis at the sn-2 position of diacylphospholipids and diacyglycerol, whereas it shows no positional specificity toward triacylglycerol. Exhibits also esterase activity toward p-nitrophenyl. May act on the brush border membrane to facilitate the absorption of digested lipids. Belongs to the 'GDSL' lipolytic enzyme family. Phospholipase B1 subfamily. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Phospholipase; EC 3.1.1.5; EC 3.1.1.4

Chromosomal Location of Human Ortholog: 2p23.2

Cellular Component: apical plasma membrane; plasma membrane; integral to membrane

Molecular Function: phospholipase A2 activity; lysophospholipase activity

Biological Process: phototransduction, visible light; phospholipid metabolic process; glycerophospholipid biosynthetic process; retinoid metabolic process; lipid catabolic process
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Research Articles on PLB1

1. identification of epidermis as a site of expression

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PLB1 antibody

 Products by Pathway  Pathway Diagram
 Acyl Chain Remodelling Of PC Pathway antibodies  Acyl Chain Remodelling Of PC Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Diseases Associated With Visual Transduction Pathway antibodies  Diseases Associated With Visual Transduction Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Glycerophospholipid Biosynthesis Pathway antibodies  Glycerophospholipid Biosynthesis Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram

Diseases associated with anti-PLB1 antibody

 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >8 publications with PLB1 and Disease Models, Animal
 Nervous System Diseases Antibodies  >5 publications with PLB1 and Nervous System Diseases
 Necrosis Antibodies  >1 publications with PLB1 and Necrosis
 Inflammation Antibodies  >1 publications with PLB1 and Inflammation
 Neoplasms Antibodies  >1 publications with PLB1 and Neoplasms
 Neoplasms, Experimental Antibodies  >1 publications with PLB1 and Neoplasms, Experimental

Organs/Tissues associated with anti-PLB1 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >5 publications with PLB1 and Lung
 Brain Antibodies  >4 publications with PLB1 and Brain
 Blood Antibodies  >3 publications with PLB1 and Blood
 Kidney Antibodies  >1 publications with PLB1 and Kidney
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