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KIRREL2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS641421

Interacts with NPHS2/podocin (via the C-terminus). Interacts with NPHS1 (via the Ig-like domains). More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KIRREL2, Monoclonal Antibody
Full Product Name
KIRREL2 (Kin of IRRE-like Protein 2, Kin of Irregular Chiasm-like Protein 2, Nephrin-like Protein 3, NEPH3, UNQ5827/PRO19646, DKFZp564A1164, MGC15718)
Product Gene Name
Product Synonym Names
Anti -KIRREL2 (Kin of IRRE-like Protein 2, Kin of Irregular Chiasm-like Protein 2, Nephrin-like Protein 3, NEPH3, UNQ5827/PRO19646, DKFZp564A1164, MGC15718)
Immunogen Sequence
MLRMRVPALL VLLFCFRGRA GPSPHLLQQP EDLVVLLGEG GAQASLGRRA SASFSEQKNL MRIPGSSDGS SSRGPEEEET GSREDRGPIV HTDHSDLVLE EEGTLETKDP TNGYYKVRGV SVSLSLGEAP GGGLFLPPPS PLGPPGTPTF YDFNPHLGMV PPCRLYRARA GYLTTPHPRA FTSYIKPTSF GPPDLAPGTP PFPYAAFPTP SHPRLQTHV
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
2B9-1D3
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human KIRREL2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
75,092 Da
Chromosome Location
Chromosome: 19; NC_000019.9 (36342552..36358048). Location: 19q13.12
OMIM
607762
3D Structure
ModBase 3D Structure for Q6UWL6
Immunogen
Full length recombinant corresponding to aa1-232 from human KIRREL2 (AAH07312) with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-KIRREL2 antibody

Applications Tested/Suitable for anti-KIRREL2 antibody
ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-KIRREL2 antibody
Suitable for use in ELISA, Western Blot and Immunoprecipitation.

Western Blot (WB) of anti-KIRREL2 antibody

Western Blot detection against Immunogen (50.2kD).
Mouse Anti-KIRREL2 Monoclonal Antibody – Cat# MBS641421

Western Blot (WB) of anti-KIRREL2 antibody

KIRREL2 monoclonal antibody, Western Blot analysis of KIRREL2 expression in Hela NE.
Mouse Anti-KIRREL2 Monoclonal Antibody, Western Blot (WB) – Cat# MBS641421

Western Blot (WB) of anti-KIRREL2 antibody

Western Blot analysis of KIRREL2 expression in transfected 293T cell line by KIRREL2 monoclonal antibody.|Lane 1: KIRREL2 transfected lysate (23.6kD).|Lane 2: Non-transfected lysate.
Mouse Anti-KIRREL2 Monoclonal Antibody, Western Blot (WB) – Cat# MBS641421

Immunoprecipitation (IP) of anti-KIRREL2 antibody

Immunoprecipitation of KIRREL2 transfected lysate using KIRREL2 monoclonal antibody and Protein A Magnetic Bead and immunoblotted with KIRREL2 rabbit polyclonal antibody.
Mouse Anti-KIRREL2 Monoclonal Antibody, Immunoprecipitation (IP) – Cat# MBS641421

Testing Data of anti-KIRREL2 antibody

Detection limit for recombinant GST tagged KIRREL2 is ~0.3ng/ml as a capture antibody.
Mouse Anti-KIRREL2 Monoclonal Antibody, Testing Data – Cat# MBS641421

Other Notes

Small volumes of anti-KIRREL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KIRREL2 purchase

MBS641421 is an antibody targeting KIRREL2. Also known as KIRREL2 (Kin of IRRE-like Protein 2, Kin of Irregular Chiasm-like Protein 2, Nephrin-like Protein 3, NEPH3, UNQ5827/PRO19646, DKFZp564A1164, MGC15718). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for KIRREL2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
kin of IRRE-like protein 2 isoform c
NCBI Official Synonym Full Names
kin of IRRE like 2 (Drosophila)
NCBI Official Symbol
KIRREL2
NCBI Official Synonym Symbols
NLG1; NEPH3; FILTRIN
UniProt Protein Name
Kin of IRRE-like protein 2
UniProt Synonym Protein Names
Kin of irregular chiasm-like protein 2; Nephrin-like protein 3
UniProt Gene Name
KIRREL2
UniProt Synonym Gene Names
NEPH3
UniProt Entry Name
KIRR2_HUMAN
NCBI Protein Information
kin of IRRE-like protein 2; nephrin-like 3; nephrin-like gene 1; nephrin-like protein 3; kin of irregular chiasm-like 2; kin of irregular chiasm-like protein 2

UniProt Comments for KIRREL2

KIRREL2: Belongs to the immunoglobulin superfamily. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 19q13.12

Cellular Component: plasma membrane; integral to membrane

Biological Process: cell-cell adhesion; negative regulation of protein amino acid phosphorylation; cell adhesion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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