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KLC2 Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS641438

MBS641438 is an antibody targeting KLC2. Also known as KLC2 (Kinesin Light Chain 2, KLC 2, FLJ12387). Reactive in Human, Rat. Host: Mouse. More details

$880 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KLC2, Polyclonal Antibody
Full Product Name
KLC2 (Kinesin Light Chain 2, KLC 2, FLJ12387)
Product Gene Name
anti-KLC2 antibody
Product Synonym Names
Anti -KLC2 (Kinesin Light Chain 2, KLC 2, FLJ12387)
Immunogen Sequence
MAMMVFPREE KLSQDEIVLG TKAVIQGLET LRGEHRALLA PLVAPEAGEA EPGSQERCIL LRRSLEAIEL GLGEAQVILA LSSHLGAVES EKQKLRAQVR RLVQENQWLR EELAGTQQKL QRSEQAVAQL EEEKQHLLFM SQIRKLDEDA SPNEEKGDVP KDTLDDLFPN EDEQSPAPSP GGGDVSGQHG GYEIPARLRT LHNLVIQYAS QGRYEVAVPL CKQALEDLEK TSGHDHPDVA TMLNILALVY RDQNKYKEAA HLLNDALAIR EKTLGKDHPA VAATLNNLAV LYGKRGKYKE AEPLCKRALE IREKVLGKFH PDVAKQLSNL ALLCQNQGKA EEVEYYYRRA LEIYATRLGP DDPNVAKTKN NLASCYLKQG KYQDAETLYK EILTRAHEKE FGSVNGDNKP IWMHAEEREE SKDKRRDSAP YGEYGSWYKA CKVDSPTVNT TLRSLGALYR RQGKLEAAHT LEDCASRNRK QGLDPASQTK VVELLKDGSG RRGDRRSSRD MAGGAGPRSE SDLEDVGPTA EWNGDGSGSL RRSGSFGKLR DALRRSSEML VKKLQGGTPQ EPPNPRMKRA SSLNFLNKSV EEPTQPGGTG LSDSRTLSSS SMDLSRRSSL VG
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human, Rat
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human KLC2. Species Crossreactivity: rat.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
68,935 Da
Chromosome Location
Chromosome: 11; NC_000011.9 (66024765..66035332). Location: 11q13.2
OMIM
611729
3D Structure
ModBase 3D Structure for Q9H0B6
Immunogen
Full length human KLC2, aa1-622 (NP_073733).

Product Categories/Family for anti-KLC2 antibody

Antibodies; Abs to Motor Proteins
Applications Tested/Suitable for anti-KLC2 antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-KLC2 antibody
Suitable for use in Immunofluorescence and Western Blot.
Dilution: Immunofluorescence: 10ug/ml

Western Blot (WB) of anti-KLC2 antibody

KLC2 polyclonal antibody. Western Blot analysis of KLC2 expression in rat brain.
Mouse Anti-KLC2 Polyclonal Antibody – Cat# MBS641438

Western Blot (WB) of anti-KLC2 antibody

Western Blot analysis of KLC2 expression in transfected 293T cell line by KLC2 polyclonal antibody. Lane 1: KLC2 transfected lysate (68.42kD). Lane 2: Non-transfected lysate.
Mouse Anti-KLC2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS641438

Immunofluorescence (IF) of anti-KLC2 antibody

Immunofluorescence of purified antibody to KLC2 on HeLa cell. [antibody concentration 10ug/ml].
Mouse Anti-KLC2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS641438

Other Notes

Small volumes of anti-KLC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KLC2. It may not necessarily be applicable to this product.

NCBI GI #
198041728
NCBI GeneID
64837
NCBI Accession #
NP_001128246.1
UniProt Primary Accession #
Q9H0B6
UniProt Secondary Accession #
Q9H9C8; Q9HA20; A8MXL7; B2RDY4
UniProt Related Accession #
Q9H0B6
GenBank Nucleotide #
NM_001134774.1
NCBI Official Full Name
kinesin light chain 2 isoform 2
NCBI Official Synonym Full Names
kinesin light chain 2
NCBI Official Symbol
KLC2
UniProt Protein Name
Kinesin light chain 2
Protein Family
Kinesin
UniProt Gene Name
KLC2
UniProt Synonym Gene Names
KLC 2
UniProt Entry Name
KLC2_HUMAN
NCBI Protein Information
kinesin light chain 2; KLC 2

NCBI Summary for KLC2

Kinesin is a molecular motor that generates ATP-dependent movement of vesicles and organelles along microtubules. Kinesin consists of 2 light chains, such as KLC2, and 2 heavy chains (see KIF5B; MIM 602809) in a 1:1 stoichiometric ratio (Rahman et al., 1998 [PubMed 9624122]).[supplied by OMIM, Mar 2008]
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UniProt Comments for KLC2

KLC2: Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity. Belongs to the kinesin light chain family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Microtubule-binding; Motor

Chromosomal Location of Human Ortholog: 11q13.2

Cellular Component: ciliary rootlet; kinesin complex; microtubule; neuron projection; protein complex; membrane; cytosol

Molecular Function: protein binding; kinesin binding; microtubule motor activity

Biological Process: metabolic process; axon cargo transport; antigen processing and presentation of exogenous peptide antigen via MHC class II; blood coagulation; microtubule-based movement
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Research Articles on KLC2

1. For the binding of cargos shared by KLC2, we propose a different site located within the groove but not involving N343.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KLC2 antibody

 Reference Product  PubMed Publications
 KLC1 antibody  >6 publications with KLC2 and KLC1
 KIF5B antibody  >5 publications with KLC2 and KIF5B
 KIF5A antibody  >3 publications with KLC2 and KIF5A
 KIF5C antibody  >2 publications with KLC2 and KIF5C

Pathways associated with anti-KLC2 antibody

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Kinesins Pathway antibodies  Kinesins Pathway Diagram
 MHC Class II Antigen Presentation Pathway antibodies  MHC Class II Antigen Presentation Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram

Organs/Tissues associated with anti-KLC2 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with KLC2 and Brain
 Nerve Antibodies  >1 publications with KLC2 and Nerve
 Prostate Antibodies  >1 publications with KLC2 and Prostate
 Muscle Antibodies  >1 publications with KLC2 and Muscle
 Lung Antibodies  >1 publications with KLC2 and Lung
 Testis Antibodies  >1 publications with KLC2 and Testis
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