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GOLPH3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS641536

The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. This protein encoded by this gene is a peripheral membrane protein of the Golgi stack and may have a regulatory role in Golgi trafficking. More details

$915 / 0.05 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GOLPH3, Polyclonal Antibody
Full Product Name
GOLPH3, NT (Golgi Phosphoprotein 3, Coat Protein GPP34, FLJ90675, GPP34, GOPP1, Mitochondrial DNA Absence Factor, MIDAS)
Product Gene Name
anti-GOLPH3 antibody
Product Synonym Names
Anti -GOLPH3, NT (Golgi Phosphoprotein 3, Coat Protein GPP34, FLJ90675, GPP34, GOPP1, Mitochondrial DNA Absence Factor, MIDAS)
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.02% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human GOLPH3. Species sequence homology: Mouse, rat.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
33,811 Da
Chromosome Location
Chromosome: 5; NC_000005.9 (32124817..32174425, complement). Location: 5p13.3
OMIM
612207
3D Structure
ModBase 3D Structure for Q9H4A6
Immunogen
Synthetic peptide corresponding to human GOLPH3 at N-terminal conjugated to KLH.

Product Categories/Family for anti-GOLPH3 antibody

Antibodies; Abs to Golgi Proteins
Applications Tested/Suitable for anti-GOLPH3 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-GOLPH3 antibody
Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: Western Blot: 0.5-1ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml

Immunohistochemistry (IHC) of anti-GOLPH3 antibody

Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-GOLPH3 Polyclonal Antibody – Cat# MBS641536

Western Blot (WB) of anti-GOLPH3 antibody

Western blot analysis of GOLPH3 in rat lung tissue lysate with GOLPH3 antibody at (A) 0.5 and (B) 1ug/ml.
Rabbit Anti-GOLPH3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS641536

Other Notes

Small volumes of anti-GOLPH3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GOLPH3 purchase

MBS641536 is an antibody targeting GOLPH3. Also known as GOLPH3, NT (Golgi Phosphoprotein 3, Coat Protein GPP34, FLJ90675, GPP34, GOPP1, Mitochondrial DNA Absence Factor, MIDAS). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GOLPH3. It may not necessarily be applicable to this product.

NCBI GI #
11545859
NCBI GeneID
64083
NCBI Accession #
NP_071413.1
UniProt Primary Accession #
Q9H4A6
UniProt Secondary Accession #
Q9UIW5
UniProt Related Accession #
Q9H4A6
GenBank Nucleotide #
NM_022130.3
NCBI Official Full Name
Golgi phosphoprotein 3
NCBI Official Synonym Full Names
golgi phosphoprotein 3 (coat-protein)
NCBI Official Symbol
GOLPH3
NCBI Official Synonym Symbols
GOPP1; GPP34; MIDAS
UniProt Protein Name
Golgi phosphoprotein 3
UniProt Synonym Protein Names
Coat protein GPP34; Mitochondrial DNA absence factor
Protein Family
Golgi phosphoprotein
UniProt Gene Name
GOLPH3
UniProt Synonym Gene Names
GPP34; MIDAS
UniProt Entry Name
GOLP3_HUMAN
NCBI Protein Information
Golgi phosphoprotein 3; coat-protein; golgi protein; coat protein GPP34; golgi-associated protein; mitochondrial DNA absence factor; golgi peripheral membrane protein 1, 34 kDa

NCBI Summary for GOLPH3

The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a peripheral membrane protein of the Golgi stack and may have a regulatory role in Golgi trafficking. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Jul 2008]
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UniProt Comments for GOLPH3

GOLPH3: Mediates the cis and medial Golgi localization of mannosyltransferases through direct binding of their cytosolic domains. Involved in modulation of mTOR signaling. Involved in the regulation of mitochondrial lipids, leading to increase of mitochondrial mass. Potential oncogene. Belongs to the GOLPH3/VPS74 family.

Protein type: Mitochondrial

Chromosomal Location of Human Ortholog: 5p13.3

Cellular Component: nucleoplasm; Golgi apparatus; Golgi cisterna; mitochondrion; plasma membrane; mitochondrial intermembrane space; trans-Golgi network; cytosol; endosome

Molecular Function: protein binding; enzyme binding

Biological Process: lamellipodium biogenesis; cell proliferation; cell migration; glycoprotein biosynthetic process; positive regulation of protein secretion; Golgi to plasma membrane protein transport; protein secretion; gene expression; Golgi vesicle budding; leukocyte tethering or rolling; Golgi organization and biogenesis; protein retention in Golgi; positive regulation of TOR signaling pathway
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Research Articles on GOLPH3

1. GOLPH3L differs critically from GOLPH3 in that it is largely unable to bind to MYO18A; data demonstrate that despite their similarities, unexpectedly, GOLPH3L antagonizes GOLPH3/MYO18A at the Golgi

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GOLPH3 antibody

 Reference Product  PubMed Publications
 MYO18A antibody  >4 publications with GOLPH3 and MYO18A
 VPS35 antibody  >1 publications with GOLPH3 and VPS35

Pathways associated with anti-GOLPH3 antibody

 Products by Pathway  Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram

Diseases associated with anti-GOLPH3 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >15 publications with GOLPH3 and Neoplasms
 Liver Diseases Antibodies  >2 publications with GOLPH3 and Liver Diseases
 Genital Diseases, Male Antibodies  >2 publications with GOLPH3 and Genital Diseases, Male
 Prostatic Diseases Antibodies  >2 publications with GOLPH3 and Prostatic Diseases
 Learning Disorders Antibodies  >1 publications with GOLPH3 and Learning Disorders
 Hyperplasia Antibodies  >1 publications with GOLPH3 and Hyperplasia

Organs/Tissues associated with anti-GOLPH3 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >4 publications with GOLPH3 and Lung
 Brain Antibodies  >4 publications with GOLPH3 and Brain
 Muscle Antibodies  >3 publications with GOLPH3 and Muscle
 Prostate Antibodies  >3 publications with GOLPH3 and Prostate
 Blood Antibodies  >2 publications with GOLPH3 and Blood
 Lymph Antibodies  >2 publications with GOLPH3 and Lymph
 Lymph Node Antibodies  >2 publications with GOLPH3 and Lymph Node
 Bone Antibodies  >1 publications with GOLPH3 and Bone
 Stomach Antibodies  >1 publications with GOLPH3 and Stomach
 Vascular Antibodies  >1 publications with GOLPH3 and Vascular
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