Rabbit Anti-KRT75 Polyclonal Antibody – Cat# MBS641578

KRT75 Antibody (N-term) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the KRT75 antibody detected the KRT75 protein (arrow).

KRT75 Antibody – Rabbit Polyclonal

Name: KRT75 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS641578
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS641578

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. This gene is expressed in the companion… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

KRT75, Polyclonal Antibody

Full Product Name

KRT75, NT (KRT75, K6HF, KB18, Keratin, type II cytoskeletal 75, Cytokeratin-75, Keratin-6 hair follicle, Keratin-75, Type II keratin-K6hf, Type-II keratin Kb18)

Product Gene Name

anti-Krt75 antibody

Product Synonym Names

Anti -KRT75, NT (KRT75, K6HF, KB18, Keratin, type II cytoskeletal 75, Cytokeratin-75, Keratin-6 hair follicle, Keratin-75, Type II keratin-K6hf, Type-II keratin Kb18)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

59,741 Da

Chromosome Location

Chromosome: 15; NC_000081.6 (101563343..101573904, complement). Location: 15 F2; 15 56.91 cM

3D Structure

ModBase 3D Structure for Q8BGZ7

Immunogen

KRT75 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-92 amino acids from the N-terminal region of human KRT75.

Product Categories/Family for anti-Krt75 antibody

Antibodies; Abs to Cytokeratin

Applications Tested/Suitable for anti-Krt75 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-Krt75 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-Krt75 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Krt75 purchase

MBS641578 is an antibody targeting Krt75. Also known as KRT75, NT (KRT75, K6HF, KB18, Keratin, type II cytoskeletal 75, Cytokeratin-75, Keratin-6 hair follicle, Keratin-75, Type II keratin-K6hf, Type-II keratin Kb18). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Krt75. It may not necessarily be applicable to this product.

NCBI GI #

29789317

NCBI GeneID

109052

NCBI Accession #

NP_579935.1

UniProt Primary Accession #

Q8BGZ7

UniProt Secondary Accession #

B2RQH6

UniProt Related Accession #

Q8BGZ7

GenBank Nucleotide #

NM_133357.3

NCBI Official Full Name

keratin, type II cytoskeletal 75

NCBI Official Synonym Full Names

keratin 75

NCBI Official Symbol

Krt75

NCBI Official Synonym Symbols

K6hf; Krtcap1; AA589387; Krt2-6hf; 4732468K03Rik

UniProt Protein Name

Keratin, type II cytoskeletal 75

UniProt Synonym Protein Names

Cytokeratin-75; CK-75; Keratin-6 hair follicle; mK6hf; Keratin-75; K75; Type II keratin-K6hf; Type-II keratin Kb18

Protein Family

Keratin

UniProt Gene Name

Krt75

UniProt Synonym Gene Names

Kb18; CK-75; mK6hf; K75

UniProt Entry Name

K2C75_MOUSE

NCBI Protein Information

keratin, type II cytoskeletal 75; K75; CK-75; mK6hf; keratin-75; cytokeratin-75; cytokeratin KRT2-6HF; type II keratin-K6hf; type-II keratin Kb18; keratin-6 hair follicle; keratinocyte associated protein 1

UniProt Comments for Krt75

KRT75: Plays a central role in hair and nail formation. Essential component of keratin intermediate filaments in the companion layer of the hair follicle. Defects in KRT75 may be a cause of loose anagen hair syndrome (LAHS). In LAHS, anagen hairs are easily pulled from the scalp. The hair is relatively sparse and does not grow long. Hair of fair color and hair shafts of reduced caliber, and an early age of onset are features. Usually the hairs are not fragile and there are no areas of breakage. Belongs to the intermediate filament family.

Protein type: Cytoskeletal

Cellular Component: keratin filament; intermediate filament; intracellular

Molecular Function: structural molecule activity

Biological Process: hemopoietic progenitor cell differentiation

Research Articles on Krt75

1. mK6a and mK75 thus exhibit temporally distinct, and spatially opposed, expression patterns in the companion layer (Cl) during postnatal anagen.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-Krt75 antibody

Disease Name	Pubmed Publications
Congenital Abnormalities Antibodies	>1 publications with Krt75 and Congenital Abnormalities
Disease Models, Animal Antibodies	>1 publications with Krt75 and Disease Models, Animal

Organs/Tissues associated with anti-Krt75 antibody

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>1 publications with Krt75 and Skin