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GTF2A1L Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS641608

The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GTF2A1L, Polyclonal Antibody
Full Product Name
GTF2A1L (ALF, GTF2A1LF, TFIIA-alpha and beta-like Factor, General Transcription Factor II A, 1-like Factor, MGC26254)
Product Gene Name
Product Synonym Names
Anti -GTF2A1L (ALF, GTF2A1LF, TFIIA-alpha and beta-like Factor, General Transcription Factor II A, 1-like Factor, MGC26254)
Immunogen Sequence
MACLNPVPKL YRSVIEDVIE GVRNLFAEEG IEEQVLKDLK QLWETKVLQS KATEDFFRNS IQSPLFTLQL PHSLHQTLQS STASLVIPAG RTLPSFTTAE LGTSNSSANF TFPGYPIHVP AGVTLQTVSG HLYKVNVPIM VTETSGRAGI LQHPIQQVFQ QLGQPSVIQT SVPQLNPWSL QATTEKSQRI ETVLQQPAIL PSGPVDRKHL ENATSDILVS PGNEHKIVPE ALLCHQESSH YISLPGVVFS PQVSQTNSNV ESVLSGSASM AQNLHDESLS TSPHGALHQH VTDIQLHILK NRMYGCDSVK QPRNIEEPSN IPVSEKDSNS QVDLSIRVTD DDIGEIIQVD GSGDTSSNEE IGSTRDADEN EFLGNIDGGD LKVPEEEADS ISNEDSATNS SDNEDPQVNI VEEDPLNSGD DVSEQDVPDL FDTDNVIVCQ YDKIHRSKNK WKFYLKDGVM CFGGRDYVFA KAIGDAEW
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human GTF2A1L.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
52,444 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (48844937..49003645). Location: 2p16.3
OMIM
605358
3D Structure
ModBase 3D Structure for Q9UNN4
Immunogen
Full length human GTF2A1L, aa1-478 (NP_006863.2).
Applications Tested/Suitable for anti-GTF2A1L antibody
Western Blot (WB)
Application Notes for anti-GTF2A1L antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-GTF2A1L antibody

Western Blot analysis of GTF2A1L expression in transfected 293T cell line by GTF2A1L polyclonal antibody. Lane 1: ALF transfected lysate (52.58kD). Lane 2: Non-transfected lysate.
Mouse Anti-GTF2A1L Polyclonal Antibody – Cat# MBS641608

Other Notes

Small volumes of anti-GTF2A1L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GTF2A1L purchase

MBS641608 is an antibody targeting GTF2A1L. Also known as GTF2A1L (ALF, GTF2A1LF, TFIIA-alpha and beta-like Factor, General Transcription Factor II A, 1-like Factor, MGC26254). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for GTF2A1L. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
GTF2A1L protein
NCBI Official Synonym Full Names
general transcription factor IIA, 1-like
NCBI Official Symbol
GTF2A1L
NCBI Official Synonym Symbols
ALF
UniProt Protein Name
TFIIA-alpha and beta-like factor
UniProt Synonym Protein Names
General transcription factor II A, 1-like factor
UniProt Gene Name
GTF2A1L
UniProt Synonym Gene Names
ALF; GTF2A1LF
UniProt Entry Name
TF2AY_HUMAN
NCBI Protein Information
TFIIA-alpha and beta-like factor; GTF2A1-like factor; TFIIA-alpha/beta-like factor; TFIIA large subunit isoform ALF; general transcription factor II A, 1-like factor

UniProt Comments for GTF2A1L

GTF2A1L: May function as a testis specific transcription factor. Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription. Belongs to the TFIIA subunit 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 2p16.3

Cellular Component: cytoplasm; transcription factor TFIIA complex

Molecular Function: DNA binding; transcription coactivator activity

Biological Process: transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; regulation of transcription, DNA-dependent; cognition
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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