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NOL6 Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS641778

MBS641778 is an antibody targeting NOL6. Also known as NOL6 (Nucleolar Protein 6, Nucleolar RNA-associated Protein, Nrap, UTP22, bA311H10.1, FLJ21959, MGC14896, MGC14921, MGC20838). Reactive in Human. Host: Mouse. Probably associated with rRNA. More details

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Product Overview

Online Datasheet in PDF
Product Name
NOL6, Polyclonal Antibody
Full Product Name
NOL6 (Nucleolar Protein 6, Nucleolar RNA-associated Protein, Nrap, UTP22, bA311H10.1, FLJ21959, MGC14896, MGC14921, MGC20838)
Product Gene Name
anti-NOL6 antibody
Product Synonym Names
Anti -NOL6 (Nucleolar Protein 6, Nucleolar RNA-associated Protein, Nrap, UTP22, bA311H10.1, FLJ21959, MGC14896, MGC14921, MGC20838)
Immunogen Sequence
MVIVTPQDRK NSVWTQDGPS AQILQQLVVL AAEALPMLEK QLMDPRGPGD IRTVFRPPLD IYDVLIRLSP RHIPRHRQAV DSPAASFCRG LLSQPGPSSL MPVLGYDPPQ LYLTQLREAF GDLALFFYDQ HGGEVIGVLW KPTSFQPQPF KASSTKGRMV MSRGGELVMV PNVEAILEDF AVLGEGLVQT VEARSERWTV
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human NOL6.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
127,593 Da
Chromosome Location
Chromosome: 9; NC_000009.11 (33461351..33473941, complement). Location: 9p13.3
OMIM
611532
3D Structure
ModBase 3D Structure for Q9H6R4
Immunogen
Full length human NOL6, aa1-201 (AAH08298).

Product Categories/Family for anti-NOL6 antibody

Antibodies; Abs to Nuclear Proteins
Applications Tested/Suitable for anti-NOL6 antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-NOL6 antibody
Suitable for use in Immunofluorescence and Western Blot.
Dilution: Immunofluorescence: 10ug/ml

Western Blot (WB) of anti-NOL6 antibody

Western Blot analysis of NOL6 expression in transfected 293T cell line by NOL6 polyclonal antibody. Lane 1: NOL6 transfected lysate (22.11kD). Lane 2: Non-transfected lysate.
Mouse Anti-NOL6 Polyclonal Antibody – Cat# MBS641778

Immunofluorescence (IF) of anti-NOL6 antibody

Immunofluorescence of purified antibody to NOL6 on HeLa cell. [antibody concentration 10ug/ml].
Mouse Anti-NOL6 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS641778

Other Notes

Small volumes of anti-NOL6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NOL6. It may not necessarily be applicable to this product.

NCBI GI #
39645213
NCBI GeneID
65083
NCBI Accession #
AAH08852.2
UniProt Primary Accession #
Q9H6R4
UniProt Secondary Accession #
Q5T5M3; Q5T5M4; Q7L4G6; Q8N6I0; Q8TEY9; Q8TEZ0; Q8TEZ1; Q9H675
UniProt Related Accession #
Q9H6R4
NCBI Official Full Name
NOL6 protein, partial
NCBI Official Synonym Full Names
nucleolar protein 6 (RNA-associated)
NCBI Official Symbol
NOL6
NCBI Official Synonym Symbols
NRAP; UTP22; bA311H10.1
UniProt Protein Name
Nucleolar protein 6
UniProt Synonym Protein Names
Nucleolar RNA-associated protein
Protein Family
Nucleolar protein
UniProt Gene Name
NOL6
UniProt Synonym Gene Names
Nrap
UniProt Entry Name
NOL6_HUMAN
NCBI Protein Information
nucleolar protein 6; nucleolar RNA-associated protein; nucleolar protein family 6 (RNA-associated)

NCBI Summary for NOL6

The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
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UniProt Comments for NOL6

NOL6: The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

Protein type: Nucleolus

Chromosomal Location of Human Ortholog: 9p13.3

Cellular Component: small subunit processome; condensed nuclear chromosome; mitochondrion; nucleolus; nucleus

Biological Process: tRNA export from nucleus; rRNA processing
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-NOL6 antibody

 Products by Pathway  Pathway Diagram
 Ribosome Biogenesis In Eukaryotes Pathway antibodies  Ribosome Biogenesis In Eukaryotes Pathway Diagram
 Ribosome Biogenesis In Eukaryotes Pathway antibodies  Ribosome Biogenesis In Eukaryotes Pathway Diagram

Organs/Tissues associated with anti-NOL6 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1 publications with NOL6 and Blood
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