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KRT73 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS641822

Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes a protein that is expressed in the inner root sheath of hair follicles.… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KRT73, Polyclonal Antibody
Full Product Name
KRT73, CT (KRT73, K6IRS3, KB36, KRT6IRS3, Keratin, type II cytoskeletal 73, Cytokeratin-73, Keratin-73, Type II inner root sheath-specific keratin-K6irs3, Type-II keratin Kb36)
Product Gene Name
Product Synonym Names
Anti -KRT73, CT (KRT73, K6IRS3, KB36, KRT6IRS3, Keratin, type II cytoskeletal 73, Cytokeratin-73, Keratin-73, Type II inner root sheath-specific keratin-K6irs3, Type-II keratin Kb36)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
58,923 Da
Chromosome Location
Chromosome: 12; NC_000012.11 (53001354..53012343, complement). Location: 12q13.3
OMIM
608247
3D Structure
ModBase 3D Structure for Q86Y46
Immunogen
KRT73 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 500-530 amino acids from the C-terminal region of human KRT73.

Product Categories/Family for anti-KRT73 antibody

Applications Tested/Suitable for anti-KRT73 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-KRT73 antibody
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50

Western Blot (WB) of anti-KRT73 antibody

KRT73 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the KRT73 antibody detected the KRT73 protein (arrow).
Rabbit Anti-KRT73 Polyclonal Antibody – Cat# MBS641822

Immunohistochemistry (IHC) of anti-KRT73 antibody

KRT73 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded m.heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KRT73 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-KRT73 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS641822

Other Notes

Small volumes of anti-KRT73 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KRT73 purchase

MBS641822 is an antibody targeting KRT73. Also known as KRT73, CT (KRT73, K6IRS3, KB36, KRT6IRS3, Keratin, type II cytoskeletal 73, Cytokeratin-73, Keratin-73, Type II inner root sheath-specific keratin-K6irs3, Type-II keratin Kb36). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KRT73. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
KRT73 protein
NCBI Official Synonym Full Names
keratin 73
NCBI Official Symbol
KRT73
NCBI Official Synonym Symbols
K6IRS3; IRT6IRS3; KRT6IRS3
UniProt Protein Name
Keratin, type II cytoskeletal 73
UniProt Synonym Protein Names
Cytokeratin-73; CK-73; Keratin-73; K73; Type II inner root sheath-specific keratin-K6irs3; Type-II keratin Kb36
Protein Family
UniProt Gene Name
KRT73
UniProt Synonym Gene Names
K6IRS3; KB36; KRT6IRS3; CK-73; K73
UniProt Entry Name
K2C73_HUMAN
NCBI Protein Information
keratin, type II cytoskeletal 73; K73; CK-73; keratin-73; cytokeratin-73; keratin 6 irs3; type-II keratin Kb36; type II inner root sheath-specific keratin-K6irs3

UniProt Comments for KRT73

K6IRS3: Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable). Belongs to the intermediate filament family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: keratin filament; nucleus

Molecular Function: structural molecule activity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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