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SH2D4A Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS641893

SH2D4A inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function. More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SH2D4A, Polyclonal Antibody
Full Product Name
SH2D4A, NT (SH2D4A, SH2A, SH2 domain-containing protein 4A, Protein SH(2)A)
Product Gene Name
Product Synonym Names
Anti -SH2D4A, NT (SH2D4A, SH2A, SH2 domain-containing protein 4A, Protein SH(2)A)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
52,727 Da
Chromosome Location
Chromosome: 8; NC_000008.10 (19171081..19253729). Location: 8p21.2
OMIM
614968
3D Structure
ModBase 3D Structure for Q9H788
Immunogen
SH2D4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-75 amino acids from the N-terminal region of human SH2D4A.

Product Categories/Family for anti-SH2D4A antibody

Applications Tested/Suitable for anti-SH2D4A antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-SH2D4A antibody
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50

Western Blot (WB) of anti-SH2D4A antibody

SH2D4A Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the SH2D4A antibody detected the SH2D4A protein (arrow).
Rabbit Anti-SH2D4A Polyclonal Antibody – Cat# MBS641893

Immunohistochemistry (IHC) of anti-SH2D4A antibody

SH2D4A Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SH2D4A Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-SH2D4A Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS641893

Other Notes

Small volumes of anti-SH2D4A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SH2D4A purchase

MBS641893 is an antibody targeting SH2D4A. Also known as SH2D4A, NT (SH2D4A, SH2A, SH2 domain-containing protein 4A, Protein SH(2)A). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SH2D4A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
SH2 domain-containing protein 4A isoform b
NCBI Official Synonym Full Names
SH2 domain containing 4A
NCBI Official Symbol
SH2D4A
NCBI Official Synonym Symbols
SH2A; PPP1R38
UniProt Protein Name
SH2 domain-containing protein 4A
UniProt Synonym Protein Names
Protein SH(2)A; Protein phosphatase 1 regulatory subunit 38
UniProt Gene Name
SH2D4A
UniProt Synonym Gene Names
PPP1R38; SH2A
UniProt Entry Name
SH24A_HUMAN
NCBI Protein Information
SH2 domain-containing protein 4A; protein SH(2)A; protein phosphatase 1 regulatory subunit 38; protein phosphatase 1, regulatory subunit 38

UniProt Comments for SH2D4A

SH2D4A: Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 8p21.2

Cellular Component: cytoplasm

Molecular Function: protein binding; phosphatase binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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