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CFHR4 Antibody – Sheep Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS641964

CFHR4 (Complement Factor H-related protein 4; also FHR4B) is a 45kD glycoprotein member of the factor H-related protein family. It is synthesized by hepatocytes and circulates in plasma. FHR4(B) binds to C3b and C3d. It also binds to native (pentameric)… More details

$1040 / 0.1 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CFHR4, Polyclonal Antibody
Full Product Name
CFHR4 (Complement Factor H-related Protein 4, FHR-4, H Factor-like Protein 4, H-Factor-like 4, H36, CFHL, CFHL4, CFHL4P, CFHR4P, FHR4, HFL4)
Product Gene Name
Product Synonym Names
Anti -CFHR4 (Complement Factor H-related Protein 4, FHR-4, H Factor-like Protein 4, H-Factor-like 4, H36, CFHL, CFHL4, CFHL4P, CFHR4P, FHR4, HFL4)
Clonality
Polyclonal
Isotype
IgG
Host
Sheep
Species Reactivity
Human
Form/Format
Supplied as a lyophilized powder in PBS with 5% trehalose. Reconstitute with sterile PBS.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human CFHR4. Species Crossreactivity: recombinant, human CFHR1, recombinant, human CFHR2 and recombinant, human CFHR5.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
37,299 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (196857144..196887843). Location: 1q32
OMIM
605337
3D Structure
ModBase 3D Structure for Q92496
Immunogen
Recombinant corresponding to human CFHR4 expressed in Sf21 (AAH74957).

Product Categories/Family for anti-CFHR4 antibody

Applications Tested/Suitable for anti-CFHR4 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-CFHR4 antibody
Suitable for use in ELISA and Western Blot.
Dilution: Direct ELISA: 0.5-1ug/ml
Western Blot: 1ug/ml

Other Notes

Small volumes of anti-CFHR4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CFHR4 purchase

MBS641964 is an antibody targeting CFHR4. Also known as CFHR4 (Complement Factor H-related Protein 4, FHR-4, H Factor-like Protein 4, H-Factor-like 4, H36, CFHL, CFHL4, CFHL4P, CFHR4P, FHR4, HFL4). Reactive in Human. Host: Sheep.

Additional Details

NCBI/Uniprot data below describe general gene information for CFHR4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
complement factor H-related protein 4 isoform 2
NCBI Official Synonym Full Names
complement factor H-related 4
NCBI Official Symbol
CFHR4
NCBI Official Synonym Symbols
FHR4; CFHL4; FHR-4
UniProt Protein Name
Complement factor H-related protein 4
UniProt Gene Name
CFHR4
UniProt Synonym Gene Names
CFHL4; FHR4; FHR-4
UniProt Entry Name
FHR4_HUMAN
NCBI Protein Information
complement factor H-related protein 4

NCBI Summary for CFHR4

This gene is a member of the complement factor H (CFH) gene family, and encodes one of the 5 CFH-related (CFHR) proteins. These 5 genes are closely linked to the CFH gene on chromosome 1q31-q32. The CFHRs are secreted plasma proteins synthesized primarily by the hepatocytes, and composed of highly-related short consensus repeats (SCRs). This protein enhances the cofactor activity of CFH, and is involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. Alternatively spliced transcript variants encoding different isoforms (varying in the number of SCRs) have been described for this gene. [provided by RefSeq, Jan 2011]
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UniProt Comments for CFHR4

CFHR4: Involved in complement regulation. Can associate with lipoproteins and may play a role in lipid metabolism.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1q32

Cellular Component: extracellular region

Molecular Function: lipid transporter activity

Biological Process: lipid transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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