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PAFAH1B3 Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS642016

Inactivates paf by removing the acetyl group at the sn-2 position. This is a catalytic subunit. Plays an important role during the development of brain. More details

$880 / 0.05 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
PAFAH1B3, Polyclonal Antibody
Full Product Name
PAFAH1B3 (Platelet-activating Factor Acetylhydrolase IB subunit gamma, PAF Acetylhydrolase 29kD Subunit, PAF-AH 29kD Subunit, PAF-AH Subunit gamma, PAFAH Subunit gamma, PAFAHG)
Product Gene Name
Product Synonym Names
Anti -PAFAH1B3 (Platelet-activating Factor Acetylhydrolase IB subunit gamma, PAF Acetylhydrolase 29kD Subunit, PAF-AH 29kD Subunit, PAF-AH Subunit gamma, PAFAH Subunit gamma, PAFAHG)
Immunogen Sequence
MSGEENPASK PTPVQDVQGD GRWMSLHHRF VADSKDKEPE VVFIGDSLVQ LMHQCEIWRE LFSPLHALNF GIGGDGTQHV LWRLENGELE HIRPKIVVVW VGTNNHGHTA EQVTGGIKAI VQLVNERQPQ ARVVVLGLLP RGQHPNPLRE KNRQVNELVR AALAGHPRAH FLDADPGFVH SDGTISHHDM YDYLHLSRLG YTPVCRALHS LLLRLLAQDQ GQGAPLLEPA P
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human PAFAH1B3.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
25,734 Da
Chromosome Location
Chromosome: 19; NC_000019.9 (42801185..42806952, complement). Location: 19q13.1
OMIM
603074
3D Structure
ModBase 3D Structure for Q15102
Immunogen
Full length human PAFAH1B3, aa1-231 (NP_002564.1).

Product Categories/Family for anti-PAFAH1B3 antibody

Applications Tested/Suitable for anti-PAFAH1B3 antibody
Western Blot (WB)
Application Notes for anti-PAFAH1B3 antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-PAFAH1B3 antibody

PAFAH1B3 polyclonal antibody. Western Blot analysis of PAFAH1B3 expression in human kidney.
Mouse Anti-PAFAH1B3 Polyclonal Antibody – Cat# MBS642016

Western Blot (WB) of anti-PAFAH1B3 antibody

Western Blot analysis of PAFAH1B3 expression in transfected 293T cell line by PAFAH1B3 polyclonal antibody. Lane 1: PAFAH1B3 transfected lysate (25.41kD). Lane 2: Non-transfected lysate.
Mouse Anti-PAFAH1B3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS642016

Other Notes

Small volumes of anti-PAFAH1B3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PAFAH1B3 purchase

MBS642016 is an antibody targeting PAFAH1B3. Also known as PAFAH1B3 (Platelet-activating Factor Acetylhydrolase IB subunit gamma, PAF Acetylhydrolase 29kD Subunit, PAF-AH 29kD Subunit, PAF-AH Subunit gamma, PAFAH Subunit gamma, PAFAHG). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PAFAH1B3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
platelet-activating factor acetylhydrolase IB subunit gamma
NCBI Official Synonym Full Names
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
NCBI Official Symbol
PAFAH1B3
NCBI Official Synonym Symbols
PAFAHG
UniProt Protein Name
Platelet-activating factor acetylhydrolase IB subunit gamma
UniProt Synonym Protein Names
PAF acetylhydrolase 29 kDa subunit; PAF-AH 29 kDa subunit; PAF-AH subunit gamma
UniProt Gene Name
PAFAH1B3
UniProt Synonym Gene Names
PAFAHG; PAF-AH 29 kDa subunit
UniProt Entry Name
PA1B3_HUMAN
NCBI Protein Information
platelet-activating factor acetylhydrolase IB subunit gamma; PAFAH subunit gamma; PAF-AH subunit gamma; PAF-AH 29 kDa subunit; PAF-AH1b alpha 1 subunit; PAF acetylhydrolase 29 kDa subunit; platelet-activating factor acetylhydrolase, isoform Ib, subunit 3 (29kDa)

NCBI Summary for PAFAH1B3

This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with mental retardation, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]
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UniProt Comments for PAFAH1B3

PAFAH1B3: Inactivates paf by removing the acetyl group at the sn-2 position. This is a catalytic subunit. Plays an important role during the development of brain. Belongs to the 'GDSL' lipolytic enzyme family. Platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily.

Protein type: EC 3.1.1.47; Lipid Metabolism - ether lipid; Lipase

Chromosomal Location of Human Ortholog: 19q13.1

Cellular Component: membrane; cytoplasm; cytosol

Molecular Function: protein binding; platelet-activating factor acetyltransferase activity; protein heterodimerization activity; 1-alkyl-2-acetylglycerophosphocholine esterase activity

Biological Process: nervous system development; spermatogenesis; brain development; lipid metabolic process; lipid catabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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