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Latexin (LXN) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS642087

Latexin, a protein possessing inhibitory activity against rat carboxypeptidase A1 (CPA1) and CPA2, is expressed in a neuronal subset in the cerebral cortex and cells in other neural and non-neural tissues of rat. Although latexin also inhibits mast-cell CPA… More details

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Product Overview

Online Datasheet in PDF
Product Name
Latexin (LXN), Polyclonal Antibody
Full Product Name
Latexin, ID (LXN, Endogenous Carboxypeptidase Inhibitor, ECI, Protein MUM, Tissue Carboxypeptidase Inhibitor)
Product Gene Name
Product Synonym Names
Anti -Latexin, ID (LXN, Endogenous Carboxypeptidase Inhibitor, ECI, Protein MUM, Tissue Carboxypeptidase Inhibitor)
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human Latexin Protein.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
25,750 Da
Chromosome Location
Chromosome: 3; NC_000003.11 (158384203..158390482, complement). Location: 3q25.32
OMIM
609305
3D Structure
ModBase 3D Structure for Q9BS40
Immunogen
Synthetic peptide corresponding from the center region of human Latexin Protein (KLH).

Product Categories/Family for anti-LXN antibody

Applications Tested/Suitable for anti-LXN antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-LXN antibody
Suitable for use in Western Blot, ELISA and Immunohistochemistry.
Dilution: ELISA: 1:1000
Western Blot: 1:50-1:100
Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml

Immunohistochemistry (IHC) of anti-LXN antibody

Human Spleen (formalin-fixed, paraffin-embedded) stained with LXN antibody followed by biotinylated goat rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.
Rabbit Anti-LXN Polyclonal Antibody – Cat# MBS642087

Western Blot (WB) of anti-LXN antibody

Western blot analysis of Latexin (arrow) in 293 cell lysates (2ug/lane) either nontransfected (Lane 1) or transiently transfected with the LXN gene (Lane 2)
Rabbit Anti-LXN Polyclonal Antibody, Western Blot (WB) – Cat# MBS642087

Other Notes

Small volumes of anti-LXN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LXN purchase

MBS642087 is an antibody targeting LXN. Also known as Latexin, ID (LXN, Endogenous Carboxypeptidase Inhibitor, ECI, Protein MUM, Tissue Carboxypeptidase Inhibitor). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LXN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
latexin
NCBI Official Synonym Full Names
latexin
NCBI Official Symbol
LXN
NCBI Official Synonym Symbols
ECI; TCI
UniProt Protein Name
Latexin
UniProt Synonym Protein Names
Endogenous carboxypeptidase inhibitor; ECI; Protein MUM; Tissue carboxypeptidase inhibitor
Protein Family
UniProt Gene Name
LXN
UniProt Synonym Gene Names
ECI; TCI
UniProt Entry Name
LXN_HUMAN
NCBI Protein Information
latexin; MUM; tissue carboxypeptidase inhibitor; endogenous carboxypeptidase inhibitor

NCBI Summary for LXN

This gene encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases. [provided by RefSeq, Oct 2008]

UniProt Comments for LXN

LXN: Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. Belongs to the protease inhibitor I47 (latexin) family.

Chromosomal Location of Human Ortholog: 3q25.32

Cellular Component: cytoplasm

Molecular Function: heparin binding; metalloendopeptidase inhibitor activity

Biological Process: detection of temperature stimulus involved in sensory perception of pain; inflammatory response
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LXN antibody

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