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GLYCTK Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS642091

This locus encodes a member of the glycerate kinase type-2 family. The encoded enzyme catalyzes the phosphorylation of (R)-glycerate and may be involved in serine degradation and fructose metabolism. Decreased activity of the encoded enzyme may be associated… More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GLYCTK, Monoclonal Antibody
Full Product Name
GLYCTK (Glycerate Kinase, CG9886-like, HBeAg-binding Protein 4, HBEBP4, HBeAgBP4A, HBEBP2, LP5910)
Product Gene Name
anti-GLYCTK antibody
Product Synonym Names
Anti -GLYCTK (Glycerate Kinase, CG9886-like, HBeAg-binding Protein 4, HBEBP4, HBeAgBP4A, HBEBP2, LP5910)
Immunogen Sequence
VLSAAMQGDV KSMAQFYGLL AHVARTRLTP SMAGASVEED AQLHELAAEL QIPDLQLEEA LETMAWGRGP VCLLAGGEPT VQLQGSGRGG RNQELALRV
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
1B5
Host
Mouse
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human GLYCTK. Species Crossreactivity: mouse.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
55,253 Da
Chromosome Location
Chromosome: 3; NC_000003.11 (52321836..52329272). Location: 3p21.1
OMIM
220120
3D Structure
ModBase 3D Structure for Q8IVS8
Immunogen
Partial recombinant protein corresponding to aa332-431 from human GLYCTK (NP_660305) with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-GLYCTK antibody

Antibodies; Abs to Protein Kinases
Applications Tested/Suitable for anti-GLYCTK antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-GLYCTK antibody
Suitable for use in ELISA and Western Blot.

Western Blot (WB) of anti-GLYCTK antibody

Western Blot detection against Immunogen (36.63kD).
Mouse Anti-GLYCTK Monoclonal Antibody – Cat# MBS642091

Western Blot (WB) of anti-GLYCTK antibody

GLYCTK monoclonal antibody. Western Blot analysis of GLYCTK expression in NIH/3T3.
Mouse Anti-GLYCTK Monoclonal Antibody, Western Blot (WB) – Cat# MBS642091

Other Notes

Small volumes of anti-GLYCTK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GLYCTK purchase

MBS642091 is an antibody targeting GLYCTK. Also known as GLYCTK (Glycerate Kinase, CG9886-like, HBeAg-binding Protein 4, HBEBP4, HBeAgBP4A, HBEBP2, LP5910). Reactive in Human, Mouse. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for GLYCTK. It may not necessarily be applicable to this product.

NCBI GI #
222418771
NCBI GeneID
132158
NCBI Accession #
NP_001138423.1
UniProt Primary Accession #
Q8IVS8
UniProt Secondary Accession #
Q0P630; Q2EZ43; Q6Y2K6; Q7Z6G5; Q86YR8; Q8TED2; Q8WTY2
UniProt Related Accession #
Q8IVS8
GenBank Nucleotide #
NM_001144951.1
NCBI Official Full Name
glycerate kinase isoform 2
NCBI Official Synonym Full Names
glycerate kinase
NCBI Official Symbol
GLYCTK
NCBI Official Synonym Symbols
HBEBP2; HBEBP4; HBeAgBP4A
UniProt Protein Name
Glycerate kinase
UniProt Synonym Protein Names
HBeAg-binding protein 4
UniProt Gene Name
GLYCTK
UniProt Synonym Gene Names
HBEBP4
UniProt Entry Name
GLCTK_HUMAN
NCBI Protein Information
glycerate kinase; HBeAg binding protein 4; HBeAg-binding protein 2

UniProt Comments for GLYCTK

GLYCTK: Defects in GLYCTK are the cause of D-glyceric aciduria (D-GA). D-GA is a rare metabolic disease characterized by chronic metabolic acidosis and a highly variable clinical phenotype. Clinical features range from an encephalopathic presentation with seizures, microcephaly, severe mental retardation and early death, to milder manifestations with only speech delay or even normal development. Belongs to the glycerate kinase type-2 family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Lipid Metabolism - glycerolipid; Carbohydrate Metabolism - glyoxylate and dicarboxylate; Amino Acid Metabolism - glycine, serine and threonine; Kinase, other; EC 2.7.1.31

Chromosomal Location of Human Ortholog: 3p21.1

Cellular Component: mitochondrion; cytoplasm

Molecular Function: protein binding; glycerate kinase activity; ATP binding

Biological Process: protein amino acid phosphorylation

Disease: D-glyceric Aciduria
Show more

Research Articles on GLYCTK

1. Mutations in the GLYCTK gene is the cause of D-glycerate kinase deficiency and D-glyceric aciduria.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-GLYCTK antibody

 Products by Pathway  Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycine, Serine And Threonine Metabolism Pathway antibodies  Glycine, Serine And Threonine Metabolism Pathway Diagram
 Glycine, Serine And Threonine Metabolism Pathway antibodies  Glycine, Serine And Threonine Metabolism Pathway Diagram
 Glyoxylate And Dicarboxylate Metabolism Pathway antibodies  Glyoxylate And Dicarboxylate Metabolism Pathway Diagram
 Glyoxylate And Dicarboxylate Metabolism Pathway antibodies  Glyoxylate And Dicarboxylate Metabolism Pathway Diagram

Diseases associated with anti-GLYCTK antibody

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >1 publications with GLYCTK and Kidney Diseases

Organs/Tissues associated with anti-GLYCTK antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1 publications with GLYCTK and Blood
 Liver Antibodies  >1 publications with GLYCTK and Liver
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