Mouse Anti-H2-K1 Monoclonal Antibody – Cat# MBS642115

C57BL/6 mouse splenocytes stained with purified H-2Kb, followed by anti-mouse IgG2a FITC

MHC Class I, H-2kb (H2-K1) Antibody – Mouse Monoclonal

Name: H2-K1 Antibody; Monoclonal; Mouse; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS642115
Price: 470 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS642115

This antibody reacts with H-2Kb MHC class I alloantigen expressed on nucleated cells from mice of the H-2Kb haplotype. H-2Kb is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins. This antibody does not cross-react with other… More details

$470 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MHC class I, H-2Kb (H2-K1), Monoclonal Antibody

Full Product Name

MHC class I, H-2Kb (MHC Class 1, H-2Kb)

Product Gene Name

anti-H2-K1 antibody

Product Synonym Names

Anti -MHC class I, H-2Kb (MHC Class 1, H-2Kb)

Clonality

Monoclonal

Isotype

IgG2a,k

Host

Mouse

Species Reactivity

Mouse

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes mouse b haplotype. Does not cross-react with other haplotypes (e.g., d, f, j, k, p, q, r, s, u, v).

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

41,302 Da

Chromosome Location

Chromosome: 17; NC_000083.6 (33996012..34000333, complement). Location: 17 B1; 17 17.98 cM

3D Structure

ModBase 3D Structure for P01901

Immunogen

C57BL mouse splenocytes

Product Categories/Family for anti-H2-K1 antibody

Antibodies; Abs to MHC

Applications Tested/Suitable for anti-H2-K1 antibody

Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)

Application Notes for anti-H2-K1 antibody

Suitable for use in Flow Cytometry, Immunohistochemistry and Immunoprecipitation.
Dilution: Flow Cytometry: 0.25ug/10e6 cells in 100ul volume

Other Notes

Small volumes of anti-H2-K1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for H2-K1 purchase

MBS642115 is an antibody targeting H2-K1. Also known as MHC class I, H-2Kb (MHC Class 1, H-2Kb). Reactive in Mouse. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for H2-K1. It may not necessarily be applicable to this product.

NCBI GI #

5531260

NCBI GeneID

14972

NCBI Accession #

CAA24119.2

UniProt Primary Accession #

P01901

UniProt Related Accession #

P01901; P01902; P03991; P04223; P14428

NCBI Official Full Name

MHC class I antigen H-2K

NCBI Official Synonym Full Names

histocompatibility 2, K1, K region

NCBI Official Symbol

H2-K1

NCBI Official Synonym Symbols

K-f; H-2K; H2-K; H-2K(d)

UniProt Protein Name

H-2 class I histocompatibility antigen, K-B alpha chain

Protein Family

H-2 class I histocompatibility antigen

UniProt Gene Name

H2-K1

UniProt Synonym Gene Names

H2-K; H-2K(B)

UniProt Entry Name

HA1B_MOUSE

NCBI Protein Information

H-2 class I histocompatibility antigen, K-W28 alpha chain; H-2K(B); H-2K(K); H-2K(Q); MHC class I antigen; MHC class I heavy chain H2-K; MHC H2-K transplantation antigen; class I major histocompatibility antigen H-2Kd; MHC class I H2-K-b-alpha-2 cell surface glycoprotein; H-2 class I histocompatibility antigen, K-B alpha chain; H-2 class I histocompatibility antigen, K-D alpha chain; H-2 class I histocompatibility antigen, K-K alpha chain; H-2 class I histocompatibility antigen, K-Q alpha chain

UniProt Comments for H2-K1

HLAC iso22: Involved in the presentation of foreign antigens to the immune system. Belongs to the MHC class I family.

Protein type: Receptor, misc.; Membrane protein, integral

Cellular Component: Golgi apparatus; cell surface; membrane; endoplasmic reticulum; integral to membrane; MHC class I protein complex; Golgi medial cisterna; external side of plasma membrane

Molecular Function: protein binding; peptide antigen binding; beta-2-microglobulin binding; protein heterodimerization activity; T cell receptor binding; peptide binding; TAP binding; receptor binding

Biological Process: antigen processing and presentation; antigen processing and presentation of peptide antigen via MHC class I; positive regulation of T cell mediated cytotoxicity; immune system process; defense response to bacterium; antigen processing and presentation of exogenous peptide antigen via MHC class I; immune response; inner ear development; antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent

Research Articles on H2-K1

1. tissue-specific h-2K(d) transgenic mice may be valuable tools for determining the mode of induction of CD8(+) T-cell responses.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-H2-K1 antibody

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Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram

Diseases associated with anti-H2-K1 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>1 publications with H2-K1 and Inflammation

Organs/Tissues associated with anti-H2-K1 antibody

Organ/Tissue Name	Pubmed Publications
Spleen Antibodies	>1 publications with H2-K1 and Spleen
Lung Antibodies	>1 publications with H2-K1 and Lung