V Beta 8.1, 8.2 (TCR) Antibody – Rat Monoclonal

The TCR Vb 8 family consists of three members, namely Vb8.1, 8.2 and 8.3. This antibody reacts with Vb8.1, 8.2 only, but not Vb8.3. Most mouse strains have about 20% Vb 8+ T cells in the periphery. However, C57BR, C57L, SJL, SWR (Tcra haplotype) and RIII strains (Tcrc haplotype) do not express Vb8 due to a gene deletion at the Vb 8 family loci. Other strains expressing endogenous super-antigen, such as Mls-1a have significant reduced number of Vb 8.1 cells in the periphery. Exogenous superantigen, such as staphylococcal enterotoxin B, stimulates lymphocytes bearing Vb 8 and selectively eliminate those T cells in vivo.

Small volumes of anti-TCR, V beta 8.1, 8.2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS642143 is an antibody targeting TCR, V beta 8.1, 8.2. Also known as TCR, V beta 8.1, 8.2 (T Cell Receptor Vb8.1, 8.2 Chain, T Cell Receptor). Reactive in Mouse. Host: Rat.