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NAT8 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS642148

This protein, isolated using the differential display method to detect tissue-specific genes, is specifically expressed in kidney and liver. The encoded protein shows amino acid sequence similarity to N-acetyltransferases. A similar protein in Xenopus affects… More details

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Product Overview

Online Datasheet in PDF
Product Name
NAT8, Polyclonal Antibody
Full Product Name
NAT8, ID (NAT8, CML1, GLA, TSC501, Probable N-acetyltransferase 8, Camello-like protein 1)
Product Gene Name
Product Synonym Names
Anti -NAT8, ID (NAT8, CML1, GLA, TSC501, Probable N-acetyltransferase 8, Camello-like protein 1)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
25,619 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (73867850..73869537, complement). Location: 2p13.2
OMIM
606716
3D Structure
ModBase 3D Structure for Q9UHE5
Immunogen
NAT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between amino acid 120-150 from the Central region of human NAT8.
Applications Tested/Suitable for anti-NAT8 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-NAT8 antibody
Suitable for use in Western Blot, Immunohistochemistry
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100

Western Blot (WB) of anti-NAT8 antibody

Western blot analysis of NAT8 Antibody (Center) in ZR-75-1 cell line lysates (35ug/lane). NAT8 (arrow) was detected using the purified Pab.
Rabbit Anti-NAT8 Polyclonal Antibody – Cat# MBS642148

Immunohistochemistry (IHC) of anti-NAT8 antibody

NAT8 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded mouse kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the NAT8 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-NAT8 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS642148

Other Notes

Small volumes of anti-NAT8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NAT8 purchase

MBS642148 is an antibody targeting NAT8. Also known as NAT8, ID (NAT8, CML1, GLA, TSC501, Probable N-acetyltransferase 8, Camello-like protein 1). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NAT8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
NAT8
NCBI Official Synonym Full Names
N-acetyltransferase 8 (GCN5-related, putative)
NCBI Official Symbol
NAT8
NCBI Official Synonym Symbols
GLA; CML1; Hcml1; ATase2; TSC501; TSC510
UniProt Protein Name
Probable N-acetyltransferase 8
UniProt Synonym Protein Names
Camello-like protein 1
Protein Family
UniProt Gene Name
NAT8
UniProt Synonym Gene Names
CML1; GLA; TSC501
UniProt Entry Name
NAT8_HUMAN
NCBI Protein Information
probable N-acetyltransferase 8; camello-like protein 1; N-acetyltransferase 8 (camello like); kidney- and liver-specific gene product

NCBI Summary for NAT8

This gene, isolated using the differential display method to detect tissue-specific genes, is specifically expressed in kidney and liver. The encoded protein shows amino acid sequence similarity to N-acetyltransferases. A similar protein in Xenopus affects cell adhesion and gastrulation movements, and may be localized in the secretory pathway. A highly similar paralog is found in a cluster with this gene. [provided by RefSeq, Sep 2008]
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UniProt Comments for NAT8

NAT8: Plays a role in regulation of gastrulation. Belongs to the camello family.

Protein type: Membrane protein, multi-pass; EC 2.3.1.80; Acetyltransferase; Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2p13.2

Cellular Component: endoplasmic reticulum membrane; ER-Golgi intermediate compartment membrane; integral to membrane; ER-Golgi intermediate compartment

Molecular Function: lysine N-acetyltransferase activity; cysteine-S-conjugate N-acetyltransferase activity; protein binding

Biological Process: response to drug; glutathione metabolic process; beta-amyloid metabolic process; peptidyl-lysine N6-acetylation; negative regulation of apoptosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NAT8 antibody

 Reference Product  PubMed Publications
 FAM122A antibody  >1 publications with NAT8 and FAM122A

Pathways associated with anti-NAT8 antibody

Organs/Tissues associated with anti-NAT8 antibody

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