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CADM4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS642158

IGSF4C/TSLL2 is a membrane glycoprotein that along with TSLL1 and TSLC1 form a unique subfamily within the immunoglobulin superfamily. TSLL2 has been shown to be lost in prostate carcinomas and gliomas, suggesting that it may play a role in tumor suppression… More details

$935 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CADM4, Polyclonal Antibody
Full Product Name
CADM4, CT (Cell Adhesion Molecule 4, IgSF4C, NECL-4, IGSF4C, NECL4, TSLL2)
Product Gene Name
Product Synonym Names
Anti -CADM4, CT (Cell Adhesion Molecule 4, IgSF4C, NECL-4, IGSF4C, NECL4, TSLL2)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a liquid in PBS, (without Mg2+, Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography
Specificity
Recognizes human CADM4/NECL-4. Species Crossreactivity: Mouse, rat.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
42,785 Da
Chromosome Location
Chromosome: 19; NC_000019.9 (44126519..44143991, complement). Location: 19q13.31
OMIM
609744
3D Structure
ModBase 3D Structure for Q8NFZ8
Immunogen
Synthetic peptide corresponding to human CADM4/NECL-4 at C-Terminal.
Applications Tested/Suitable for anti-CADM4 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-CADM4 antibody
Suitable for use in Immunofluorescence, ELISA, Western Blot, Immunohistochemistry.
Dilution: Immunofluorescence: 1:100-1:500
ELISA: 1:20,000
Western Blot: 1:500-1:1000
Immunohistochemistry (Paraffin): 10ug/ml

Immunohistochemistry (IHC) of anti-CADM4 antibody

Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-CADM4 Polyclonal Antibody – Cat# MBS642158

Western Blot (WB) of anti-CADM4 antibody

Western blot analysis of extracts from RAW264.7 cells, using CADM4. The lane on the right is treated with the synthesized peptide.
Rabbit Anti-CADM4 Polyclonal Antibody, Western Blot (WB) – Cat# MBS642158

Immunofluorescence (IF) of anti-CADM4 antibody

Immunofluorescence analysis of A549 cells, using CADM4. The picture on the right is treated with the synthesized peptide.
Rabbit Anti-CADM4 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS642158

Other Notes

Small volumes of anti-CADM4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CADM4 purchase

MBS642158 is an antibody targeting CADM4. Also known as CADM4, CT (Cell Adhesion Molecule 4, IgSF4C, NECL-4, IGSF4C, NECL4, TSLL2). Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CADM4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cell adhesion molecule 4
NCBI Official Synonym Full Names
cell adhesion molecule 4
NCBI Official Symbol
CADM4
NCBI Official Synonym Symbols
NECL4; TSLL2; IGSF4C; Necl-4; synCAM4
UniProt Protein Name
Cell adhesion molecule 4
UniProt Synonym Protein Names
Immunoglobulin superfamily member 4C; IgSF4C; Nectin-like protein 4; NECL-4; TSLC1-like protein 2
UniProt Gene Name
CADM4
UniProt Synonym Gene Names
IGSF4C; NECL4; TSLL2; IgSF4C; NECL-4
UniProt Entry Name
CADM4_HUMAN
NCBI Protein Information
cell adhesion molecule 4; TSLC1-like 2; nectin-like 4; TSLC1-like protein 2; nectin-like protein 4; immunoglobulin superfamily member 4C; immunoglobulin superfamily, member 4C

UniProt Comments for CADM4

CADM4: Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity. Belongs to the nectin family.

Protein type: Membrane protein, integral; Cell adhesion; Tumor suppressor

Chromosomal Location of Human Ortholog: 19q13.31

Cellular Component: integral to membrane

Biological Process: cell adhesion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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