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KLF2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS642256

KLF2 (Kruppel-like factor 2; endothelium, monocytes, Taa in length. It contains an activation domain aa1-110, an inhibitory domain aa111-267, and three C2H2-type zinc-finger regions aa272-354. There is one potential splice form that shows a premature… More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KLF2, Monoclonal Antibody
Full Product Name
KLF2 (Kruppel-like Factor 2, Lung Kruppel-like Factor, LKLF, Lung Kruppel-like Zinc Finger Transcription Factor, Kruppel-like Factor LKLF)
Product Gene Name
Product Synonym Names
Anti -KLF2 (Kruppel-like Factor 2, Lung Kruppel-like Factor, LKLF, Lung Kruppel-like Zinc Finger Transcription Factor, Kruppel-like Factor LKLF)
Immunogen Sequence
SWPRKRTATH TCSYAGCGKT YTKSSHLKAH LRTHTGEKPY HCNWDGCGWK FARSDELTRH YRKHTGHRPF QCHLCDRAFS RSDHLALH
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
1D1
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human KLF2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
37,420 Da
Chromosome Location
Chromosome: 19; NC_000019.9 (16435651..16438345). Location: 19p13.11
OMIM
602016
3D Structure
ModBase 3D Structure for Q9Y5W3
Immunogen
Partial recombinant corresponding to aa263-350 from KLF2 (NP_057354) with GST tag. MW of the GST tag alone is 26kD.
Applications Tested/Suitable for anti-KLF2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-KLF2 antibody
Suitable for use in Western Blot and ELISA.

Western Blot (WB) of anti-KLF2 antibody

Western Blot detection against Immunogen (35.53kD).
Mouse Anti-KLF2 Monoclonal Antibody – Cat# MBS642256

Other Notes

Small volumes of anti-KLF2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KLF2 purchase

MBS642256 is an antibody targeting KLF2. Also known as KLF2 (Kruppel-like Factor 2, Lung Kruppel-like Factor, LKLF, Lung Kruppel-like Zinc Finger Transcription Factor, Kruppel-like Factor LKLF). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for KLF2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Krueppel-like factor 2
NCBI Official Synonym Full Names
Kruppel-like factor 2 (lung)
NCBI Official Symbol
KLF2
NCBI Official Synonym Symbols
LKLF
UniProt Protein Name
Krueppel-like factor 2
UniProt Synonym Protein Names
Lung krueppel-like factor
Protein Family
UniProt Gene Name
KLF2
UniProt Synonym Gene Names
LKLF
UniProt Entry Name
KLF2_HUMAN
NCBI Protein Information
Krueppel-like factor 2; Kruppel-like factor LKLF; lung krueppel-like factor; lung Kruppel-like zinc finger transcription factor

NCBI Summary for KLF2

Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1; MIM 601974) and the selectin CD62L (SELL; MIM 153240) (summary by Weinreich et al., 2009 [PubMed 19592277]).[supplied by OMIM, Feb 2011]
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UniProt Comments for KLF2

KLF2: Binds to the CACCC box in the beta-globin gene promoter and activates transcription. Belongs to the krueppel C2H2-type zinc-finger protein family.

Protein type: C2H2-type zinc finger protein; DNA-binding

Chromosomal Location of Human Ortholog: 19p13.11

Cellular Component: nucleus

Molecular Function: protein binding; sequence-specific DNA binding; metal ion binding; transcription factor activity

Biological Process: erythrocyte maturation; transcription, DNA-dependent; in utero embryonic development; multicellular organism growth; negative regulation of interleukin-6 production; cell morphogenesis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of protein metabolic process; regulation of gene expression, epigenetic
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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