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MYL6B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS642387

Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in both slow-twitch… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Product Overview

Online Datasheet in PDF
Product Name
MYL6B, Polyclonal Antibody
Full Product Name
MYL6B, ID (MYL6B, MLC1SA, Myosin light chain 6B, Myosin light chain 1 slow-twitch muscle A isoform, Smooth muscle and nonmuscle myosin light chain alkali 6B)
Product Gene Name
Product Synonym Names
Anti -MYL6B, ID (MYL6B, MLC1SA, Myosin light chain 6B, Myosin light chain 1 slow-twitch muscle A isoform, Smooth muscle and nonmuscle myosin light chain alkali 6B)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
22,764 Da
Chromosome Location
Chromosome: 12; NC_000012.11 (56546040..56551771). Location: 12q13.13
OMIM
609930
3D Structure
ModBase 3D Structure for P14649
Immunogen
MYL6B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-123 amino acids from the Central region of human MYL6B.

Product Categories/Family for anti-MYL6B antibody

Applications Tested/Suitable for anti-MYL6B antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-MYL6B antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-MYL6B antibody

MYL6B Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the MYL6B antibody detected the MYL6B protein (arrow).
Rabbit Anti-MYL6B Polyclonal Antibody – Cat# MBS642387

Other Notes

Small volumes of anti-MYL6B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MYL6B purchase

MBS642387 is an antibody targeting MYL6B. Also known as MYL6B, ID (MYL6B, MLC1SA, Myosin light chain 6B, Myosin light chain 1 slow-twitch muscle A isoform, Smooth muscle and nonmuscle myosin light chain alkali 6B). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MYL6B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
myosin light chain 6B
NCBI Official Synonym Full Names
myosin, light chain 6B, alkali, smooth muscle and non-muscle
NCBI Official Symbol
MYL6B
NCBI Official Synonym Symbols
MLC1SA
UniProt Protein Name
Myosin light chain 6B
UniProt Synonym Protein Names
Myosin light chain 1 slow-twitch muscle A isoform; MLC1sa; Smooth muscle and nonmuscle myosin light chain alkali 6B
Protein Family
UniProt Gene Name
MYL6B
UniProt Synonym Gene Names
MLC1SA; MLC1sa
UniProt Entry Name
MYL6B_HUMAN
NCBI Protein Information
myosin light chain 6B; myosin light chain 1 slow a; myosin alkali light chain 1 slow a; myosin light chain 1 slow-twitch muscle A isoform; myosin light chain 1, slow-twitch muscle A isoform; smooth muscle and nonmuscle myosin light chain alkali 6B; smooth muscle and non-muscle myosin alkali light chain 6B; myosin, light polypeptide 6B, alkali, smooth muscle and non-muscle

NCBI Summary for MYL6B

Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in both slow-twitch skeletal muscle and in nonmuscle tissue. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
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UniProt Comments for MYL6B

MYL6B: Regulatory light chain of myosin. Does not bind calcium.

Protein type: Motility/polarity/chemotaxis; Contractile

Chromosomal Location of Human Ortholog: 12q13.13

Cellular Component: unconventional myosin complex; muscle myosin complex; cytosol; myosin complex

Molecular Function: protein binding; structural constituent of muscle; motor activity; calcium ion binding

Biological Process: skeletal muscle development; muscle contraction; metabolic process; muscle filament sliding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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