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RHPN2 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS642448

MBS642448 is an antibody targeting RHPN2. Also known as RHPN2, ID (Rhophilin-2, 76kD RhoB Effector Protein, GTP-Rho-binding Protein 2, p76RBE). Reactive in Human. Host: Goat. More details

$785 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RHPN2, Polyclonal Antibody
Full Product Name
RHPN2, ID (Rhophilin-2, 76kD RhoB Effector Protein, GTP-Rho-binding Protein 2, p76RBE)
Product Gene Name
Product Synonym Names
Anti -RHPN2, ID (Rhophilin-2, 76kD RhoB Effector Protein, GTP-Rho-binding Protein 2, p76RBE)
Clonality
Polyclonal
Host
Goat
Species Reactivity
Human
Form/Format
Supplied as a liquid in TBS, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human RHPN2. Species sequence homology: Mouse and rat.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
76,993 Da
Chromosome Location
Chromosome: 19; NC_000019.9 (33469498..33555824, complement). Location: 19q13.11
3D Structure
ModBase 3D Structure for Q8IUC4
Immunogen
Synthetic peptide corresponding to internal region of human RHPN2 (KLH).
Applications Tested/Suitable for anti-RHPN2 antibody
ELISA (EL/EIA), Immunohistochemistry (IHC)
Application Notes for anti-RHPN2 antibody
Suitable for use in ELISA and Immunohistochemistry.
Dilution: ELISA: 1:32,000
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml

Immunohistochemistry (IHC) of anti-RHPN2 antibody

Human Kidney (formalin-fixed, paraffin-embedded) stained with RHPN2 antibody at 5ug/ml followed by biotinylated anti-goat IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.
Goat Anti-RHPN2 Polyclonal Antibody – Cat# MBS642448

Other Notes

Small volumes of anti-RHPN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RHPN2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
rhophilin-2
NCBI Official Synonym Full Names
rhophilin, Rho GTPase binding protein 2
NCBI Official Symbol
RHPN2
NCBI Official Synonym Symbols
RHOBP; P76RBE
UniProt Protein Name
Rhophilin-2
UniProt Synonym Protein Names
76 kDa RhoB effector protein; GTP-Rho-binding protein 2; p76RBE
Protein Family
UniProt Gene Name
RHPN2
UniProt Entry Name
RHPN2_HUMAN
NCBI Protein Information
rhophilin-2; rhophilin 2; GTP-Rho-binding protein 2; 76 kDa RhoB effector protein; rhophilin-like Rho-GTPase binding protein

NCBI Summary for RHPN2

This gene encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase binding proteins. The encoded protein binds both GTP- and GDP-bound RhoA and GTP-bound RhoB and may be involved in the organization of the actin cytoskeleton. [provided by RefSeq, Apr 2009]

UniProt Comments for RHPN2

RHPN2: Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity. Belongs to the RHPN family.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 19q13.11

Cellular Component: nucleoplasm; intracellular membrane-bound organelle; perinuclear region of cytoplasm; cytoplasm

Biological Process: signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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