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ECM29 Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS642465

Adapter/scaffolding protein that binds to the 26S proteasome, motor proteins and other compartment specific proteins. May couple the proteasome to different compartments including endosome, endoplasmic reticulum and centrosome. May play a role in ERAD and… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ECM29, Polyclonal Antibody
Full Product Name
ECM29 (KIAA0368, Proteasome-associated Protein ECM29 Homolog, Ecm29)
Product Gene Name
Product Synonym Names
Anti -ECM29 (KIAA0368, Proteasome-associated Protein ECM29 Homolog, Ecm29)
Immunogen Sequence
MDSARLSAAK SSPMMETINM CLQYLDVSVL GELVPRLCEL IRSGVGLGTK GGCASVIVSL TTQCPQDLTP YSGKLMSALL SGLTDRNSVI QKSCAFAMGH LVRTSRDSST EKLLQKLNGW YMEKEEPIYK TSCALTIHAI GRYSPDVLKN HAKEVLPLAF LGMHEIADEE KSEKEECNLW TEVWQENVPG SFGGIRLYLQ ELITITQKAL QSQSWKMKAQ GAIAMASIAK QTSSLVPPYL GMILTALLQG LAGRTWAGKE ELLKAIACVV TACSAELEKS VPNQPSTNEI LQAVLKECSK ENVKYKIVAI SCAADILKAT KEDRFQEFSN IVIPLIKKNS LESSGVRTTK NEEENEKEKE LQLEYLLGAF ESLGKAWPRN AETQRCYRQE LCKLMCERLK LSTWKVQLGV LQSMNAFFQG LMLLEEEHAD PEALAEILLE TCKSITYSLE NKTYSSVRTE ALSVIELLLK KLEESKQWEC LTSECRVLLI ESLATMEPDS RPELQEKAAL LKKTLENLE
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human KIAA0368.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
210,431 Da
Chromosome Location
Chromosome: VIII; NC_001140.6 (40084..45690). Location: chromosome: VIII
3D Structure
ModBase 3D Structure for P38737
Immunogen
Full length human KIAA0368, aa1-519 (AAH21127.1).

Product Categories/Family for anti-ECM29 antibody

Applications Tested/Suitable for anti-ECM29 antibody
Western Blot (WB)
Application Notes for anti-ECM29 antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-ECM29 antibody

KIAA0368 polyclonal antibody. Western Blot analysis of KIAA0368 expression in human placenta.
Mouse Anti-ECM29 Polyclonal Antibody – Cat# MBS642465

Western Blot (WB) of anti-ECM29 antibody

Western Blot analysis of KIAA0368 expression in transfected 293T cell line by KIAA0368 polyclonal antibody. Lane 1: KIAA0368 transfected lysate (57.09kD). Lane 2: Non-transfected lysate.
Mouse Anti-ECM29 Polyclonal Antibody, Western Blot (WB) – Cat# MBS642465

Other Notes

Small volumes of anti-ECM29 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ECM29 purchase

MBS642465 is an antibody targeting ECM29. Also known as ECM29 (KIAA0368, Proteasome-associated Protein ECM29 Homolog, Ecm29). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ECM29. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Ecm29p
NCBI Official Symbol
ECM29
UniProt Protein Name
Proteasome component ECM29
UniProt Synonym Protein Names
Extracellular mutant protein 29
Protein Family
UniProt Gene Name
ECM29
UniProt Entry Name
ECM29_YEAST
NCBI Protein Information
Ecm29p

UniProt Comments for ECM29

Function: Stabilizes the proteasome holoenzyme, probably by tethering the 20S proteolytic core particle and the 19S regulatory particle. The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Ref.4

Subunit structure: Component of the proteasome. ECM29 binds to both proteasome 19S and 20S particles. Ref.4

Subcellular location: Cytoplasm. Nucleus Ref.5.

Miscellaneous: Present with 2950 molecules/cell in log phase SD medium.

Sequence similarities: Belongs to the ECM29 family.Contains 24 HEAT repeats.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ECM29 antibody

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