Mouse Anti-FBXL20 Monoclonal Antibody – Cat# MBS642697

FBXL20 Antibody – Mouse Monoclonal

Name: FBXL20 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS642697
Price: 880 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS642697

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Role in neural transmission. More details

$880 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FBXL20, Monoclonal Antibody

Full Product Name

FBXL20 (F-box/LRR-repeat Protein 20, F-box and Leucine-rich Repeat Protein 20, F-box/LRR-repeat Protein 2-like, FBL2, MGC15482)

Product Gene Name

anti-FBXL20 antibody

Product Synonym Names

Anti -FBXL20 (F-box/LRR-repeat Protein 20, F-box and Leucine-rich Repeat Protein 20, F-box/LRR-repeat Protein 2-like, FBL2, MGC15482)

Immunogen Sequence

MRRDVNGVTK SRFEMFSNSD EAVINKKLPK ELLLRIFSFL DVVTLCRCAQ VSRAWNVLAL DGSNWQRIDL FDFQRDIEGR VVENISKRCG GFLRKLSLRG CLGVGDNALR TFAQNCRNIE VLNLNGCTKT TDATCTSLSK FCSKLRHLDL ASCTSITNMS LKALSEGCPL LEQLNISWCD QVTKDGIQAL VRGCGGLKAL FLKGCTQLED EALKYIGAHC PELVTLNLQT CLQITDEGLI TICRGCHKLQ SLCASGCSNI TDAILNALGQ NCPRLRILEV ARCSQLTDVG FTTLARNCHE LEKMDLEECV QITDSTLIQL SIHCPRLQVL SLSHCELITD DGIRHLGNGA CAHDQLEVIE LDNCPLITDA SLEHLKSCHS LERIELYDCQ QITRAGIKRL RTHLPNIKVH AYFAPVTPPP SVGGSRQRFC RCCIIL

Clonality

Monoclonal

Isotype

IgG1,k

Clone Number

2G1

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human FBXL20.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

48,423 Da

Chromosome Location

Chromosome: 17; NC_000017.10 (37408897..37558530, complement). Location: 17q12

OMIM

609086

3D Structure

ModBase 3D Structure for Q96IG2

Immunogen

Full length recombinant corresponding to aa1-437 from human FBXL20 (AAH07557) with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-FBXL20 antibody

Antibodies; Abs to Ubiquitin Ligases

Applications Tested/Suitable for anti-FBXL20 antibody

ELISA (EL/EIA)

Application Notes for anti-FBXL20 antibody

Suitable for use in ELISA.

Other Notes

Small volumes of anti-FBXL20 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FBXL20 purchase

MBS642697 is an antibody targeting FBXL20. Also known as FBXL20 (F-box/LRR-repeat Protein 20, F-box and Leucine-rich Repeat Protein 20, F-box/LRR-repeat Protein 2-like, FBL2, MGC15482). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for FBXL20. It may not necessarily be applicable to this product.

NCBI GI #

296531375

NCBI GeneID

84961

NCBI Accession #

NP_001171835.1

UniProt Primary Accession #

Q96IG2

UniProt Secondary Accession #

Q38J52; A8K729

UniProt Related Accession #

Q96IG2

GenBank Nucleotide #

NM_001184906.1

NCBI Official Full Name

F-box/LRR-repeat protein 20 isoform 2

NCBI Official Synonym Full Names

F-box and leucine-rich repeat protein 20

NCBI Official Symbol

FBXL20

NCBI Official Synonym Symbols

Fbl2; Fbl20

UniProt Protein Name

F-box/LRR-repeat protein 20

UniProt Synonym Protein Names

F-box and leucine-rich repeat protein 20; F-box/LRR-repeat protein 2-like

Protein Family

F-box/LRR-repeat protein

UniProt Gene Name

FBXL20

UniProt Synonym Gene Names

FBL2

UniProt Entry Name

FXL20_HUMAN

NCBI Protein Information

F-box/LRR-repeat protein 20; F-box protein FBL2

NCBI Summary for FBXL20

Members of the F-box protein family, such as FBXL20, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]

UniProt Comments for FBXL20

FBXL20: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Role in neural transmission. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: cytoplasm

Biological Process: behavioral fear response

Research Articles on FBXL20

1. study concludes FBXL20 plays an essential role in the carcinogenesis of colorectal adenocarcinoma and promotes carcinogenesis through the regulation of the Wnt signaling pathway and caspase activation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-FBXL20 antibody

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>1 publications with FBXL20 and Kidney
Blood Antibodies	>1 publications with FBXL20 and Blood
Brain Antibodies	>1 publications with FBXL20 and Brain