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RARRES3 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS642744

RIG-I, also known as Probable ATP-dependent RNA helicase DDX58, is a regulatory enzyme involved in innate immune defense against viruses. RIG-I, usually present in vascular smooth cells, interacts with intracellular dsRNA produced during viral replication and… More details

$835 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RIG1 (RARRES3), Polyclonal Antibody
Full Product Name
RIG1 (Probable ATP-dependent RNA Helicase DDX58, DEAD Box Protein 58, Retinoic Acid-inducible Gene 1 Protein, RIG-1, Retinoic Acid-inducible Gene I Protein, RIG-I, DDX58)
Product Gene Name
Product Synonym Names
Anti -RIG1 (Probable ATP-dependent RNA Helicase DDX58, DEAD Box Protein 58, Retinoic Acid-inducible Gene 1 Protein, RIG-1, Retinoic Acid-inducible Gene I Protein, RIG-I, DDX58)
Clonality
Polyclonal
Host
Goat
Species Reactivity
Human
Form/Format
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Purity/Purification
Purified
Purified
Specificity
Recognizes human RIG1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
18,179 Da
Chromosome Location
Chromosome: 11; NC_000011.9 (63304273..63313930). Location: 11q23
OMIM
605092
3D Structure
ModBase 3D Structure for Q9UL19

Product Categories/Family for anti-RARRES3 antibody

Applications Tested/Suitable for anti-RARRES3 antibody
Immunohistochemistry (IHC)
Application Notes for anti-RARRES3 antibody
Suitable for use in Immunohistochemistry.
Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 3.75ug/ml

Immunohistochemistry (IHC) of anti-RARRES3 antibody

Brain, cortex, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)
Goat Anti-RARRES3 Polyclonal Antibody – Cat# MBS642744

Immunohistochemistry (IHC) of anti-RARRES3 antibody

Placenta, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)
Goat Anti-RARRES3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS642744

Immunohistochemistry (IHC) of anti-RARRES3 antibody

Spleen, Human: Formalin-Fixed, Paraffin-Embedded (FFP
Goat Anti-RARRES3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS642744

Other Notes

Small volumes of anti-RARRES3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RARRES3 purchase

MBS642744 is an antibody targeting RARRES3. Also known as RIG1 (Probable ATP-dependent RNA Helicase DDX58, DEAD Box Protein 58, Retinoic Acid-inducible Gene 1 Protein, RIG-1, Retinoic Acid-inducible Gene I Protein, RIG-I, DDX58). Reactive in Human. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for RARRES3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
retinoic acid receptor responder protein 3
NCBI Official Synonym Full Names
retinoic acid receptor responder (tazarotene induced) 3
NCBI Official Symbol
RARRES3
NCBI Official Synonym Symbols
RIG1; TIG3; HRSL4; HRASLS4; PLA1/2-3
UniProt Protein Name
Retinoic acid receptor responder protein 3
UniProt Synonym Protein Names
HRAS-like suppressor 4; HRSL4; RAR-responsive protein TIG3; Retinoid-inducible gene 1 protein; Tazarotene-induced gene 3 protein
UniProt Gene Name
RARRES3
UniProt Synonym Gene Names
RIG1; TIG3; HRSL4
UniProt Entry Name
HRSL4_HUMAN
NCBI Protein Information
retinoic acid receptor responder protein 3; HRAS-like suppressor 4; RAR-responsive protein TIG3; retinoic acid-inducible gene 1; retinoid-inducible gene 1 protein; tazarotene-induced gene 3 protein

NCBI Summary for RARRES3

Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator. [provided by RefSeq, Jul 2008]
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UniProt Comments for RARRES3

RARRES3: Exhibits PLA1/2 activity, catalyzing the calcium- independent hydrolysis of acyl groups in various phosphotidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. N- and O-acylation activity is hardly detectable. Belongs to the H-rev107 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.1.-; Cell cycle regulation

Chromosomal Location of Human Ortholog: 11q23

Cellular Component: integral to membrane

Molecular Function: phospholipase A2 activity; protein binding

Biological Process: negative regulation of cell proliferation; phospholipid metabolic process; lipid catabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RARRES3 antibody

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