Rabbit Anti-REXO2 Polyclonal Antibody – Cat# MBS642824

REXO2 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the REXO2 antibody detected the REXO2 protein (arrow).

REXO2 Antibody – Rabbit Polyclonal

Name: REXO2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS642824
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS642824

Nucleases are components of DNA and RNA metabolism that carry out functions in DNA repair, replication, and recombination and in RNA processing and degradation. SFN is a homolog of Orn, a 3-prime-to-5-prime exoribonuclease of E. coli that attacks the free… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

REXO2, Polyclonal Antibody

Full Product Name

REXO2, ID (REXO2, SFN, SMFN, Oligoribonuclease, mitochondrial, RNA exonuclease 2 homolog, Small fragment nuclease)

Product Gene Name

anti-REXO2 antibody

Product Synonym Names

Anti -REXO2, ID (REXO2, SFN, SMFN, Oligoribonuclease, mitochondrial, RNA exonuclease 2 homolog, Small fragment nuclease)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

26,833 Da

Chromosome Location

Chromosome: 11; NC_000011.9 (114310108..114321001). Location: 11q23.2

OMIM

607149

3D Structure

ModBase 3D Structure for Q9Y3B8

Immunogen

REXO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-157 amino acids from the Central region of human REXO2.

Product Categories/Family for anti-REXO2 antibody

Antibodies; Abs to Enzymes; Exonuclease

Applications Tested/Suitable for anti-REXO2 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-REXO2 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-REXO2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for REXO2 purchase

MBS642824 is an antibody targeting REXO2. Also known as REXO2, ID (REXO2, SFN, SMFN, Oligoribonuclease, mitochondrial, RNA exonuclease 2 homolog, Small fragment nuclease). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for REXO2. It may not necessarily be applicable to this product.

NCBI GI #

79158846

NCBI GeneID

25996

NCBI Accession #

AAI07888.1

UniProt Primary Accession #

Q9Y3B8

UniProt Secondary Accession #

Q32Q18; Q53FT1; Q6FIC6; Q9UFY7

UniProt Related Accession #

Q9Y3B8

NCBI Official Full Name

REXO2 protein

NCBI Official Synonym Full Names

RNA exonuclease 2

NCBI Official Symbol

REXO2

NCBI Official Synonym Symbols

RFN; SFN; REX2; CGI-114

UniProt Protein Name

Oligoribonuclease, mitochondrial

UniProt Synonym Protein Names

RNA exonuclease 2 homolog; Small fragment nuclease

UniProt Gene Name

REXO2

UniProt Synonym Gene Names

SFN; SMFN

UniProt Entry Name

ORN_HUMAN

NCBI Protein Information

oligoribonuclease, mitochondrial; small fragment nuclease; RNA exonuclease 2 homolog; REX2, RNA exonuclease 2 homolog

NCBI Summary for REXO2

This gene encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process. [provided by RefSeq, Nov 2011]

UniProt Comments for REXO2

REXO2: a 3'-to-5' exoribonuclease specific for small oligoribonucleotides. Active on small (primarily </=5 nucleotides in length) single-stranded RNA and DNA oligomers. May have a role for cellular nucleotide recycling. Two splice variant isoforms have been described: mitochondrial (isoform 1) and nuclear (isoform 2).

Protein type: Hydrolase; EC 3.1.-.-

Chromosomal Location of Human Ortholog: 11q23.2

Cellular Component: focal adhesion; mitochondrion; mitochondrial matrix; nucleolus; mitochondrial intermembrane space; nucleus

Molecular Function: 3'-5'-exoribonuclease activity; nucleic acid binding; 3'-5' exonuclease activity

Biological Process: nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; nucleotide metabolic process

Research Articles on REXO2

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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