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FUT4 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS642867

The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15). More details

$865 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FUT4, Monoclonal Antibody
Full Product Name
FUT4 (FUT4, ELFT, FCT3A, Alpha-(1,3)-fucosyltransferase, ELAM-1 ligand fucosyltransferase, Fucosyltransferase 4, Fucosyltransferase IV, Galactoside 3-L-fucosyltransferase)
Product Gene Name
anti-Fut4 antibody
Product Synonym Names
Anti -FUT4 (FUT4, ELFT, FCT3A, Alpha-(1,3)-fucosyltransferase, ELAM-1 ligand fucosyltransferase, Fucosyltransferase 4, Fucosyltransferase IV, Galactoside 3-L-fucosyltransferase)
Clonality
Monoclonal
Isotype
IgM
Clone Number
476CT26.8.4
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
49,481 Da
Chromosome Location
Chromosome: 9; NC_000075.6 (14748459..14752122, complement). Location: 9 A2; 9 4.3 cM
3D Structure
ModBase 3D Structure for Q11127
Immunogen
Purified His-tagged FUT4 protein (fragment).

Product Categories/Family for anti-Fut4 antibody

Antibodies; Abs to Enzymes; Glycosyltransferase
Applications Tested/Suitable for anti-Fut4 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-Fut4 antibody
Suitable for use in Western Blot, ELISA.
Dilution: ELISA: 1:1,000
Western Blot: 1:100~250

Western Blot (WB) of anti-Fut4 antibody

FUT4 Antibody western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the FUT4 antibody detected the FUT4 protein (arrow).
Mouse Anti-FUT4 Monoclonal Antibody – Cat# MBS642867

Other Notes

Small volumes of anti-Fut4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Fut4 purchase

MBS642867 is an antibody targeting Fut4. Also known as FUT4 (FUT4, ELFT, FCT3A, Alpha-(1,3)-fucosyltransferase, ELAM-1 ligand fucosyltransferase, Fucosyltransferase 4, Fucosyltransferase IV, Galactoside 3-L-fucosyltransferase). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for Fut4. It may not necessarily be applicable to this product.

NCBI GI #
187953611
NCBI GeneID
14345
NCBI Accession #
AAI37589.1
UniProt Primary Accession #
Q11127
UniProt Related Accession #
Q11127
NCBI Official Full Name
Fut4 protein
NCBI Official Synonym Full Names
fucosyltransferase 4
NCBI Official Symbol
Fut4
NCBI Official Synonym Symbols
FAL; LeX; CD15; Ssea1; SSEA-1; FucT-IV; AI451562
UniProt Protein Name
Alpha-(1,3)-fucosyltransferase 4
UniProt Synonym Protein Names
Fucosyltransferase 4; Fucosyltransferase IV; Fuc-TIV; FucT-IV; Galactoside 3-L-fucosyltransferase
Protein Family
Alpha-(1,3)-fucosyltransferase
UniProt Gene Name
Fut4
UniProt Synonym Gene Names
Elft; Fuc-TIV; FucT-IV
UniProt Entry Name
FUT4_MOUSE
NCBI Protein Information
alpha-(1,3)-fucosyltransferase 4; alpha-(1,3)-fucosyltransferase 4; Lewis x; fuc-TIV; fucosyltransferase IV; alpha 1,3-fucosyltransferase; galactoside 3-L-fucosyltransferase; stage-specific embryonic antigen 1; 3-fucosyl-N-acetyl-lactosamine epitope; alpha (1,3) fucosyltransferase, myeloid specific

UniProt Comments for Fut4

FUT4: May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens. Belongs to the glycosyltransferase 10 family.

Protein type: EC 2.4.1.-; Transferase; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; Membrane protein, integral

Cellular Component: Golgi apparatus; cell surface; membrane; integral to membrane

Molecular Function: oligosaccharyl transferase activity; acetylgalactosaminyltransferase activity; alpha(1,6)-fucosyltransferase activity; alpha(1,3)-fucosyltransferase activity; glucosyltransferase activity; O antigen polymerase activity; alpha-1,2-mannosyltransferase activity; acetylglucosaminyltransferase activity; transferase activity, transferring glycosyl groups; 1-phenanthrol glycosyltransferase activity; phenanthrol glycosyltransferase activity; glycolipid mannosyltransferase activity; galactosyltransferase activity; dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity; fucosyltransferase activity; dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity; lipopolysaccharide-1,6-galactosyltransferase activity; alpha-1,3-galactosyltransferase activity; alpha-1,2-galactosyltransferase activity; dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity; 9-phenanthrol UDP-glucuronosyltransferase activity; UDP-glucose:glycoprotein glucosyltransferase activity; 1,2-dihydroxy-phenanthrene glycosyltransferase activity; transferase activity; 9-phenanthrol glycosyltransferase activity; dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity; cellulose synthase activity; beta-1,4-mannosyltransferase activity; mannosyltransferase activity; alpha-1,3-mannosyltransferase activity; alpha-1,6-mannosyltransferase activity; inositol phosphoceramide synthase activity

Biological Process: protein amino acid glycosylation
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Research Articles on Fut4

1. LRP1 is necessary for the differentiation of neural stem cells toward oligodendrocytes. However, this function is independent of LeX glycosylation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-Fut4 antibody

 Products by Pathway  Pathway Diagram
 Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway antibodies  Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway Diagram
 Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway antibodies  Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway Diagram
 Other Types Of O-glycan Biosynthesis Pathway antibodies  Other Types Of O-glycan Biosynthesis Pathway Diagram
 Other Types Of O-glycan Biosynthesis Pathway antibodies  Other Types Of O-glycan Biosynthesis Pathway Diagram

Diseases associated with anti-Fut4 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >9 publications with Fut4 and Inflammation
 Necrosis Antibodies  >7 publications with Fut4 and Necrosis
 Brain Diseases Antibodies  >5 publications with Fut4 and Brain Diseases
 Nervous System Diseases Antibodies  >4 publications with Fut4 and Nervous System Diseases
 Lung Diseases Antibodies  >4 publications with Fut4 and Lung Diseases
 Central Nervous System Diseases Antibodies  >4 publications with Fut4 and Central Nervous System Diseases
 Lymphoma Antibodies  >4 publications with Fut4 and Lymphoma
 Lung Neoplasms Antibodies  >3 publications with Fut4 and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >2 publications with Fut4 and Neoplasms, Experimental
 Liver Diseases Antibodies  >2 publications with Fut4 and Liver Diseases

Organs/Tissues associated with anti-Fut4 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >9 publications with Fut4 and Brain
 Lung Antibodies  >6 publications with Fut4 and Lung
 Bone Antibodies  >6 publications with Fut4 and Bone
 Uterus Antibodies  >6 publications with Fut4 and Uterus
 Kidney Antibodies  >5 publications with Fut4 and Kidney
 Lymph Node Antibodies  >5 publications with Fut4 and Lymph Node
 Embryonic Tissue Antibodies  >4 publications with Fut4 and Embryonic Tissue
 Skin Antibodies  >3 publications with Fut4 and Skin
 Liver Antibodies  >2 publications with Fut4 and Liver
 Intestine Antibodies  >2 publications with Fut4 and Intestine
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