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TACSTD2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643043

MBS643043 is an antibody targeting TACSTD2. Also known as Tacstd2, CT (Tacstd2, Trop2, Tumor-associated calcium signal transducer 2, Cell surface glycoprotein Trop-2). Reactive in Mouse. Host: Rabbit. Tacstd2 may function as a growth factor receptor (By… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Tacstd2, Polyclonal Antibody
Full Product Name
Tacstd2, CT (Tacstd2, Trop2, Tumor-associated calcium signal transducer 2, Cell surface glycoprotein Trop-2)
Product Gene Name
anti-TACSTD2 antibody
Product Synonym Names
Anti -Tacstd2, CT (Tacstd2, Trop2, Tumor-associated calcium signal transducer 2, Cell surface glycoprotein Trop-2)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Mouse
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
35,709 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (59041095..59043166, complement). Location: 1p32
OMIM
137290
3D Structure
ModBase 3D Structure for P09758
Immunogen
Mouse Tacstd2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-246 amino acids from the C-terminal region of mouse Tacstd2.

Product Categories/Family for anti-TACSTD2 antibody

Antibodies; Abs to Carbohydrates; Glycoproteins
Applications Tested/Suitable for anti-TACSTD2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-TACSTD2 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-TACSTD2 antibody

Western Blot analysis of mouse liver tissue lysates (35ug/lane) using MBS643043. This demonstrates that MBS643043 detected the Tacstd2 protein (arrow).
Rabbit Anti-TACSTD2 Polyclonal Antibody – Cat# MBS643043

Other Notes

Small volumes of anti-TACSTD2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TACSTD2. It may not necessarily be applicable to this product.

NCBI GI #
166795236
NCBI GeneID
4070
NCBI Accession #
NP_002344.2
UniProt Primary Accession #
P09758
UniProt Secondary Accession #
Q15658; Q6FG48; Q7Z7Q4; Q96QD2
UniProt Related Accession #
P09758
GenBank Nucleotide #
NM_002353.2
NCBI Official Full Name
tumor-associated calcium signal transducer 2
NCBI Official Synonym Full Names
tumor-associated calcium signal transducer 2
NCBI Official Symbol
TACSTD2
NCBI Official Synonym Symbols
EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1
UniProt Protein Name
Tumor-associated calcium signal transducer 2
UniProt Synonym Protein Names
Cell surface glycoprotein Trop-2; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733-1
Protein Family
Tumor-associated calcium signal transducer
UniProt Gene Name
TACSTD2
UniProt Synonym Gene Names
GA733-1; M1S1; TROP2
UniProt Entry Name
TACD2_HUMAN
NCBI Protein Information
tumor-associated calcium signal transducer 2; epithelial glycoprotein-1; cell surface glycoprotein TROP2; cell surface glycoprotein Trop-2; pancreatic carcinoma marker protein GA7331; pancreatic carcinoma marker protein GA733-1; gastrointestinal tumor-associated antigen GA7331; membrane component chromosome 1 surface marker 1; membrane component, chromosome 1, surface marker 1; 40kD glycoprotein, identified by monoclonal antibody GA733

NCBI Summary for TACSTD2

This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009]

UniProt Comments for TACSTD2

TACSTD2: May function as a growth factor receptor. Defects in TACSTD2 are the cause of gelatinous drop-like corneal dystrophy (GDLD); also known as lattice corneal dystrophy type III. GDLD is an autosomal recessive disorder characterized by grayish corneal amyloid deposits that cause severe visual impairment. Belongs to the EPCAM family.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 1p32

Cellular Component: extracellular space; membrane; integral to plasma membrane; basal plasma membrane; cytosol; nucleus; lateral plasma membrane

Molecular Function: protein binding; receptor activity

Biological Process: cell proliferation; negative regulation of stress fiber formation; cell surface receptor linked signal transduction; visual perception; regulation of epithelial cell proliferation

Disease: Corneal Dystrophy, Gelatinous Drop-like
Show more

Research Articles on TACSTD2

1. show that Trop-2 enhances directional prostate cancer cell migration, through modulation of Rac1 GTPase activity

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-TACSTD2 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >46 publications with TACSTD2 and Neoplasms
 Adenocarcinoma Antibodies  >11 publications with TACSTD2 and Adenocarcinoma
 Prostatic Diseases Antibodies  >8 publications with TACSTD2 and Prostatic Diseases
 Prostatic Neoplasms Antibodies  >8 publications with TACSTD2 and Prostatic Neoplasms
 Neoplasms, Experimental Antibodies  >7 publications with TACSTD2 and Neoplasms, Experimental
 Breast Neoplasms Antibodies  >6 publications with TACSTD2 and Breast Neoplasms
 Ovarian Diseases Antibodies  >5 publications with TACSTD2 and Ovarian Diseases
 Ovarian Neoplasms Antibodies  >5 publications with TACSTD2 and Ovarian Neoplasms
 Lung Neoplasms Antibodies  >4 publications with TACSTD2 and Lung Neoplasms
 Lung Diseases Antibodies  >4 publications with TACSTD2 and Lung Diseases

Organs/Tissues associated with anti-TACSTD2 antibody

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >15 publications with TACSTD2 and Eye
 Prostate Antibodies  >10 publications with TACSTD2 and Prostate
 Liver Antibodies  >7 publications with TACSTD2 and Liver
 Lymph Node Antibodies  >6 publications with TACSTD2 and Lymph Node
 Lung Antibodies  >5 publications with TACSTD2 and Lung
 Skin Antibodies  >2 publications with TACSTD2 and Skin
 Uterus Antibodies  >2 publications with TACSTD2 and Uterus
 Bone Antibodies  >2 publications with TACSTD2 and Bone
 Bone Marrow Antibodies  >1 publications with TACSTD2 and Bone Marrow
 Intestine Antibodies  >1 publications with TACSTD2 and Intestine
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