Mouse Anti-ASZ1 Monoclonal Antibody – Cat# MBS643064

Western Blot detection against Immunogen (37.99kD).

ASZ1 Antibody – Mouse Monoclonal

Name: ASZ1 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS643064
Price: 880 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643064

Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during… More details

$880 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ASZ1, Monoclonal Antibody

Full Product Name

ASZ1 (Ankyrin Repeat, SAM and Basic Leucine Zipper Domain-containing Protein 1, Ankyrin-like Protein 1, Germ Cell-specific Ankyrin, SAM and Basic Leucine Zipper Domain-containing Protein, ALP1, ANKL1, C7orf7, GASZ, MGC26634, Orf3, CT1.19)

Product Gene Name

anti-ASZ1 antibody

Product Synonym Names

Anti -ASZ1 (Ankyrin Repeat, SAM and Basic Leucine Zipper Domain-containing Protein 1, Ankyrin-like Protein 1, Germ Cell-specific Ankyrin, SAM and Basic Leucine Zipper Domain-containing Protein, ALP1, ANKL1, C7orf7, GASZ, MGC26634, Orf3, CT1.19)

Immunogen Sequence

QILKCVELLL SRNADPNVAC RRLMTPIMYA ARDGHTQVVA LLVAHGAEVN TQDENGYTAL TWAARQGHKN IVLKLLELGA NKMLQTKDGK MPSEIAKRNK HHEIFNLL

Clonality

Monoclonal

Isotype

IgG2b,k

Clone Number

3C9

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human ASZ1.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

53,458 Da

Chromosome Location

Chromosome: 7; NC_000007.13 (117003276..117067577, complement). Location: 7q31.2

OMIM

605797

3D Structure

ModBase 3D Structure for Q8WWH4

Immunogen

Partial recombinant protein corresponding to aa127-235 from human ASZ1 (NP_570124) with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-ASZ1 antibody

Antibodies; Abs to Leucine Zipper Proteins

Applications Tested/Suitable for anti-ASZ1 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-ASZ1 antibody

Suitable for use in ELISA and Western Blot.

Other Notes

Small volumes of anti-ASZ1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ASZ1 purchase

MBS643064 is an antibody targeting ASZ1. Also known as ASZ1 (Ankyrin Repeat, SAM and Basic Leucine Zipper Domain-containing Protein 1, Ankyrin-like Protein 1, Germ Cell-specific Ankyrin, SAM and Basic Leucine Zipper Domain-containing Protein, ALP1, ANKL1, C7orf7, GASZ, MGC26634, Orf3, CT1.19). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ASZ1. It may not necessarily be applicable to this product.

NCBI GI #

219519054

NCBI GeneID

136991

NCBI Accession #

AAI44213.1

UniProt Primary Accession #

Q8WWH4

UniProt Secondary Accession #

A0AV27; A4D0V0

UniProt Related Accession #

Q8WWH4

NCBI Official Full Name

ASZ1 protein

NCBI Official Synonym Full Names

ankyrin repeat, SAM and basic leucine zipper domain containing 1

NCBI Official Symbol

ASZ1

NCBI Official Synonym Symbols

ALP1; GASZ; Orf3; ANKL1; C7orf7; CT1.19

UniProt Protein Name

Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1

UniProt Synonym Protein Names

Ankyrin-like protein 1; Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein

Protein Family

Ankyrin repeat, SAM and basic leucine zipper domain-containing protein

UniProt Gene Name

ASZ1

UniProt Synonym Gene Names

ALP1; ANKL1; C7orf7; GASZ

UniProt Entry Name

ASZ1_HUMAN

NCBI Protein Information

ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; 4933400N19Rik; ankyrin-like 1; ankyrin-like protein 1; germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein

UniProt Comments for ASZ1

ASZ1: Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 7q31.2

Cellular Component: cytoplasm

Molecular Function: signal transducer activity

Biological Process: DNA methylation during gametogenesis; multicellular organismal development; gene expression; RNA-mediated gene silencing; spermatogenesis; male meiosis; cell differentiation; signal transduction

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-ASZ1 antibody

Disease Name	Pubmed Publications
Infertility, Female Antibodies	>1 publications with ASZ1 and Infertility, Female
Neoplasms Antibodies	>1 publications with ASZ1 and Neoplasms
Infertility, Male Antibodies	>1 publications with ASZ1 and Infertility, Male
Respiratory Tract Diseases Antibodies	>1 publications with ASZ1 and Respiratory Tract Diseases

Organs/Tissues associated with anti-ASZ1 antibody

Organ/Tissue Name	Pubmed Publications
Testis Antibodies	>2 publications with ASZ1 and Testis