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LEFTY1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643151

LEFTB is a member of the TGF-beta family of proteins. A similar secreted protein in mouse plays a role in left-right asymmetry determination of organ systems during development. Alternative processing of this protein can yield three different products. More details

$970 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
LEFTY1, Polyclonal Antibody
Full Product Name
LEFTY1 (Left-right Determination Factor 1, Left-right Determination Factor B, Protein Lefty-1, Protein Lefty-B, LEFTB, LEFTYB, UNQ278/PRO317)
Product Gene Name
Product Synonym Names
Anti -LEFTY1 (Left-right Determination Factor 1, Left-right Determination Factor B, Protein Lefty-1, Protein Lefty-B, LEFTB, LEFTYB, UNQ278/PRO317)
Immunogen Sequence
MQPLWLCWAL WVLPLASPGA ALTGEQLLGS LLRQLQLKEV PTLDRADMEE LVIPTHVRAQ YVALLQRSHG DRSRGKRFSQ SFREVAGRFL ALEASTHLLV FGMEQRLPPN SELVQAVLRL FQEPVPKAAL HRHGRLSPRS ARARVTVEWL RVRDDGSNRT SLIDSRLVSV HESGWKAFDV TEAVNFWQQL SRPRQPLLLQ VSVQREHLGP LASGAHKLVR FASQGAPAGL GEPQLELHTL DLGDYGAQGD CDPEAPMTEG TRCCRQEMYI DLQGMKWAEN WVLEPPGFLA YECVGTCRQP PEALAFKWPF LGPRQCIASE TDSLPMIVSI KEGGRTRPQV VSLPNMRVQK CSCASDGALV PRRLQP
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human LEFTY1. Species Crossreactivity: mouse.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
40,880 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (226073982..226076846, complement). Location: 1q42.1
OMIM
603037
3D Structure
ModBase 3D Structure for O75610
Immunogen
Full-length human LEFTY1, aa1-366 (NP_066277.1).
Applications Tested/Suitable for anti-LEFTY1 antibody
Western Blot (WB)
Application Notes for anti-LEFTY1 antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-LEFTY1 antibody

LEFTY1 rabbit polyclonal antibody. Western Blot analysis of LEFTY1 expression in mouse liver.
Rabbit Anti-LEFTY1 Polyclonal Antibody – Cat# MBS643151

Western Blot (WB) of anti-LEFTY1 antibody

Western Blot analysis of LEFTY1 expression in transfected 293T cell line by LEFTY1 polyclonal antibody. Lane 1: LEFTY1 transfected lysate (40.9kD). Lane 2: Non-transfected lysate.
Rabbit Anti-LEFTY1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS643151

Other Notes

Small volumes of anti-LEFTY1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LEFTY1 purchase

MBS643151 is an antibody targeting LEFTY1. Also known as LEFTY1 (Left-right Determination Factor 1, Left-right Determination Factor B, Protein Lefty-1, Protein Lefty-B, LEFTB, LEFTYB, UNQ278/PRO317). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LEFTY1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
left-right determination factor 1 preproprotein
NCBI Official Synonym Full Names
left-right determination factor 1
NCBI Official Symbol
LEFTY1
NCBI Official Synonym Symbols
LEFTB; LEFTYB
UniProt Protein Name
Left-right determination factor 1
UniProt Synonym Protein Names
Left-right determination factor B; Protein lefty-1; Protein lefty-B
UniProt Gene Name
LEFTY1
UniProt Synonym Gene Names
LEFTB; LEFTYB
UniProt Entry Name
LFTY1_HUMAN
NCBI Protein Information
left-right determination factor 1; protein lefty-1; protein lefty-B; left-right determination factor B; left-right determination, factor B

NCBI Summary for LEFTY1

This gene encodes a member of the TGF-beta family of proteins. A similar secreted protein in mouse plays a role in left-right asymmetry determination of organ systems during development. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq, Jul 2008]
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UniProt Comments for LEFTY1

LEFTY1: Required for left-right axis determination as a regulator of LEFTY2 and NODAL. Belongs to the TGF-beta family.

Protein type: Secreted; Ligand, receptor tyrosine kinase; Secreted, signal peptide; Cytokine; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 1q42.1

Cellular Component: extracellular space

Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: heart morphogenesis; regulation of apoptosis; regulation of MAPKKK cascade; transforming growth factor beta receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; cell growth; determination of left/right symmetry; cell development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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