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SNTG2 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643267

Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a… More details

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Product Overview

Online Datasheet in PDF
Product Name
SNTG2, Polyclonal Antibody
Full Product Name
SNTG2 (Gamma-2-syntrophin, G2SYN, Syntrophin-5, SYN5)
Product Gene Name
Product Synonym Names
Anti -SNTG2 (Gamma-2-syntrophin, G2SYN, Syntrophin-5, SYN5)
Clonality
Polyclonal
Host
Goat
Species Reactivity
Human
Form/Format
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human SNTG2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
60,217 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (946554..1371401). Location: 2p25.3
OMIM
608715
3D Structure
ModBase 3D Structure for Q9NY99
Immunogen
Synthetic peptide corresponding to C-DSQSLARKYMYSS, from human SNTG2, at C-terminal (NP_061841.2).
Applications Tested/Suitable for anti-SNTG2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-SNTG2 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:16,000
Western Blot: 0.1-0.3ug/ml, observed in human duodenum Ileum lysates on ~70kD bands

Chemiluminescence of anti-SNTG2 antibody

(0.3ug/ml) staining of Human Duodenum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-SNTG2 Polyclonal Antibody – Cat# MBS643267

Other Notes

Small volumes of anti-SNTG2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SNTG2 purchase

MBS643267 is an antibody targeting SNTG2. Also known as SNTG2 (Gamma-2-syntrophin, G2SYN, Syntrophin-5, SYN5). Reactive in Human. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for SNTG2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
SNTG2 protein
NCBI Official Synonym Full Names
syntrophin, gamma 2
NCBI Official Symbol
SNTG2
NCBI Official Synonym Symbols
SYN5; G2SYN
UniProt Protein Name
Gamma-2-syntrophin
UniProt Synonym Protein Names
Syntrophin-5
Protein Family
UniProt Gene Name
SNTG2
UniProt Synonym Gene Names
G2SYN; SYN5
UniProt Entry Name
SNTG2_HUMAN
NCBI Protein Information
gamma-2-syntrophin; syntrophin-5

NCBI Summary for SNTG2

This gene encodes a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described. [provided by RefSeq, Jul 2008]
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UniProt Comments for SNTG2

SNTG2: Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. Belongs to the syntrophin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 2p25.3

Cellular Component: cytoskeleton; cytoplasm; syntrophin complex; sarcolemma

Molecular Function: actin binding; PDZ domain binding

Biological Process: central nervous system development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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