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SH3PXD2A Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643282

Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that… More details

$720 / 0.05 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SH3PXD2A, Polyclonal Antibody
Full Product Name
SH3PXD2A (SH3 and PX Domain-containing Protein 2A, Adapter Protein TKS5, Five SH3 Domain-containing Protein, SH3 Multiple Domains Protein 1, Tyrosine Kinase Substrate with Five SH3 Domains, FISH, KIAA0418, SH3MD1, TKS5)
Product Gene Name
Product Synonym Names
Anti -SH3PXD2A (SH3 and PX Domain-containing Protein 2A, Adapter Protein TKS5, Five SH3 Domain-containing Protein, SH3 Multiple Domains Protein 1, Tyrosine Kinase Substrate with Five SH3 Domains, FISH, KIAA0418, SH3MD1, TKS5)
Clonality
Polyclonal
Host
Goat
Species Reactivity
Human
Form/Format
Supplied as a liquid in Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human SH3PXD2A.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
125,289 Da
Chromosome Location
Chromosome: 10; NC_000010.10 (105353784..105615195, complement). Location: 10q24.33
3D Structure
ModBase 3D Structure for Q5TCZ1
Immunogen
Synthetic peptide corresponding to C-KPIEKSQFIHNNLK from aa1033-1046 of human SH3PXD2A (NP_055446.2).
Applications Tested/Suitable for anti-SH3PXD2A antibody
Immunohistochemistry (IHC)
Application Notes for anti-SH3PXD2A antibody
Suitable for use in Immunohistochemistry.
Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 3.75-7.5ug/ml

Immunohistochemistry (IHC) of anti-SH3PXD2A antibody

Formalin- fixed, paraffin-embedded (FFPE) human liver using MBS643282.
Goat Anti-SH3PXD2A Polyclonal Antibody – Cat# MBS643282

Immunohistochemistry (IHC) of anti-SH3PXD2A antibody

Formalin- fixed, paraffin-embedded (FFPE) human small intestine using MBS643282.
Goat Anti-SH3PXD2A Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS643282

Other Notes

Small volumes of anti-SH3PXD2A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SH3PXD2A purchase

MBS643282 is an antibody targeting SH3PXD2A. Also known as SH3PXD2A (SH3 and PX Domain-containing Protein 2A, Adapter Protein TKS5, Five SH3 Domain-containing Protein, SH3 Multiple Domains Protein 1, Tyrosine Kinase Substrate with Five SH3 Domains, FISH, KIAA0418, SH3MD1, TKS5). Reactive in Human. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for SH3PXD2A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
SH3 and PX domain-containing protein 2A
NCBI Official Synonym Full Names
SH3 and PX domains 2A
NCBI Official Symbol
SH3PXD2A
NCBI Official Synonym Symbols
FISH; TKS5; SH3MD1
UniProt Protein Name
SH3 and PX domain-containing protein 2A
UniProt Synonym Protein Names
Adapter protein TKS5; Five SH3 domain-containing protein; SH3 multiple domains protein 1; Tyrosine kinase substrate with five SH3 domains
UniProt Gene Name
SH3PXD2A
UniProt Synonym Gene Names
FISH; KIAA0418; SH3MD1; TKS5
UniProt Entry Name
SPD2A_HUMAN
NCBI Protein Information
SH3 and PX domain-containing protein 2A; adapter protein TKS5; adaptor protein TKS5; SH3 multiple domains 1; five SH3 domain-containing protein; tyrosine kinase substrate with five SH3 domains

UniProt Comments for SH3PXD2A

Tks5: a scaffolding protein required for podosome formation, degradation of the extracellular matrix, and for invasion in some cancer cells. Other phox proteins are involved in vesicular trafficking, protein sorting and lipid modification.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 10q24.33

Cellular Component: cell projection; cytoplasm; podosome; cell junction

Molecular Function: protein binding; phosphoinositide binding

Biological Process: superoxide metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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