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MESP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643283

Mesp1 is a transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways. More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Mesp1, Polyclonal Antibody
Full Product Name
Mesp1, ID (Mesp1, Mesoderm posterior protein 1)
Product Gene Name
anti-MESP1 antibody
Product Synonym Names
Anti -Mesp1, ID (Mesp1, Mesoderm posterior protein 1)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Mouse
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
28,501 Da
Chromosome Location
Chromosome: 15; NC_000015.9 (90293098..90294540, complement). Location: 15q26.1
OMIM
608689
3D Structure
ModBase 3D Structure for Q9BRJ9
Immunogen
Mouse Mesp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-91 amino acids from the Central region of Mouse Mesp1.

Product Categories/Family for anti-MESP1 antibody

Antibodies; Abs to Cardiac Markers
Applications Tested/Suitable for anti-MESP1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-MESP1 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-MESP1 antibody

Mouse Mesp1 Antibody (Center) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the MESP1 antibody detected the MESP1 protein (arrow).
Rabbit Anti-MESP1 Polyclonal Antibody – Cat# MBS643283

Other Notes

Small volumes of anti-MESP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MESP1 purchase

MBS643283 is an antibody targeting MESP1. Also known as Mesp1, ID (Mesp1, Mesoderm posterior protein 1). Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MESP1. It may not necessarily be applicable to this product.

NCBI GI #
14149724
NCBI GeneID
55897
NCBI Accession #
NP_061140.1
UniProt Primary Accession #
Q9BRJ9
UniProt Secondary Accession #
Q9NSF1; Q9NSF2
UniProt Related Accession #
Q9BRJ9
GenBank Nucleotide #
NM_018670.3
NCBI Official Full Name
mesoderm posterior protein 1
NCBI Official Synonym Full Names
mesoderm posterior 1 homolog (mouse)
NCBI Official Symbol
MESP1
NCBI Official Synonym Symbols
bHLHc5
UniProt Protein Name
Mesoderm posterior protein 1
UniProt Synonym Protein Names
Class C basic helix-loop-helix protein 5
Protein Family
Mesoderm posterior protein
UniProt Gene Name
MESP1
UniProt Synonym Gene Names
BHLHC5; bHLHc5
UniProt Entry Name
MESP1_HUMAN
NCBI Protein Information
mesoderm posterior protein 1; class C basic helix-loop-helix protein 5

UniProt Comments for MESP1

MESP1: Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways.

Protein type: Cell development/differentiation; Transcription factor

Chromosomal Location of Human Ortholog: 15q26.1

Cellular Component: nucleus

Molecular Function: protein dimerization activity; transcription factor activity

Biological Process: endothelial cell differentiation; Notch signaling pathway; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; lateral mesoderm development; gastrulation; positive regulation of striated muscle cell differentiation; mesodermal cell migration; cardiac muscle cell differentiation; negative regulation of mesodermal cell fate specification; neurogenesis; negative regulation of endodermal cell fate specification; positive regulation of transcription from RNA polymerase II promoter; heart looping; negative regulation of transcription, DNA-dependent; positive regulation of Notch signaling pathway
Show more

Research Articles on MESP1

1. Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MESP1 antibody

 Reference Product  PubMed Publications
 DLL1 antibody  >3 publications with MESP1 and DLL1
 LFNG antibody  >3 publications with MESP1 and LFNG
 HES5 antibody  >2 publications with MESP1 and HES5
 FOXC1 antibody  >1 publications with MESP1 and FOXC1
 SOX17 antibody  >1 publications with MESP1 and SOX17
 FOXC2 antibody  >1 publications with MESP1 and FOXC2

Pathways associated with anti-MESP1 antibody

 Products by Pathway  Pathway Diagram
 Cardiac Progenitor Differentiation Pathway antibodies  Cardiac Progenitor Differentiation Pathway Diagram

Diseases associated with anti-MESP1 antibody

 Disease Name  Pubmed Publications
 Heart Defects, Congenital Antibodies  >6 publications with MESP1 and Heart Defects, Congenital
 Abnormalities, Multiple Antibodies  >3 publications with MESP1 and Abnormalities, Multiple
 Liver Diseases Antibodies  >2 publications with MESP1 and Liver Diseases
 Arteriosclerosis Antibodies  >1 publications with MESP1 and Arteriosclerosis

Organs/Tissues associated with anti-MESP1 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >38 publications with MESP1 and Muscle
 Connective Tissue Antibodies  >5 publications with MESP1 and Connective Tissue
 Testis Antibodies  >2 publications with MESP1 and Testis
 Kidney Antibodies  >2 publications with MESP1 and Kidney
 Brain Antibodies  >2 publications with MESP1 and Brain
 Eye Antibodies  >1 publications with MESP1 and Eye
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