Rabbit Anti-ARCN1 Polyclonal Antibody – Cat# MBS643289

ARCN1 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the ARCN1 antibody detected the ARCN1 protein (arrow).

ARCN1 Antibody – Rabbit Polyclonal

Name: ARCN1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS643289
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643289

This gene maps in a region, which include the mixed lineage leukemia and Friend leukemia virus integration 1 genes, where multiple disease-associated chromosome translocations occur. It is an intracellular protein. Archain sequences are well conserved among… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ARCN1, Polyclonal Antibody

Full Product Name

ARCN1, ID (ARCN1, COPD, Coatomer subunit delta, Archain, Delta-coat protein)

Product Gene Name

anti-ARCN1 antibody

Product Synonym Names

Anti -ARCN1, ID (ARCN1, COPD, Coatomer subunit delta, Archain, Delta-coat protein)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

57,210 Da

Chromosome Location

Chromosome: 11; NC_000011.9 (118443078..118473748). Location: 11q23.3

OMIM

600820

3D Structure

ModBase 3D Structure for P48444

Immunogen

ARCN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 295-324 amino acids from the Central region of human ARCN1.

Product Categories/Family for anti-ARCN1 antibody

Antibodies; Abs to Proteins

Applications Tested/Suitable for anti-ARCN1 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-ARCN1 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-ARCN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARCN1 purchase

MBS643289 is an antibody targeting ARCN1. Also known as ARCN1, ID (ARCN1, COPD, Coatomer subunit delta, Archain, Delta-coat protein). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ARCN1. It may not necessarily be applicable to this product.

NCBI GI #

40675522

NCBI GeneID

372

NCBI Accession #

AAH64936.1

UniProt Primary Accession #

P48444

UniProt Secondary Accession #

Q52M80; B4E1X2; E9PEU4

UniProt Related Accession #

P48444

NCBI Official Full Name

ARCN1 protein

NCBI Official Synonym Full Names

archain 1

NCBI Official Symbol

ARCN1

NCBI Official Synonym Symbols

COPD

UniProt Protein Name

Coatomer subunit delta

UniProt Synonym Protein Names

Archain; Delta-coat protein

Protein Family

Coatomer

UniProt Gene Name

ARCN1

UniProt Synonym Gene Names

COPD; Delta-COP

UniProt Entry Name

COPD_HUMAN

NCBI Protein Information

coatomer subunit delta; delta-COP; delta-coat protein; coatomer delta subunit; coatomer protein delta-COP; archain vesicle transport protein 1; coatomer protein complex, subunit delta

UniProt Comments for ARCN1

ARCN1: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: Golgi apparatus; clathrin adaptor complex; membrane; intracellular membrane-bound organelle; endoplasmic reticulum; cytoplasm; COPI vesicle coat; cytosol

Biological Process: cerebellar Purkinje cell layer maturation; intracellular protein transport; COPI coating of Golgi vesicle; pigmentation; adult locomotory behavior; retrograde vesicle-mediated transport, Golgi to ER

Research Articles on ARCN1

1. Single nucleotide polymorphisms in the PHLDB1 and ARCN1 genes are associated with increased risk of Glioma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ARCN1 antibody

Products by Pathway	Pathway Diagram
COPI Mediated Transport Pathway antibodies	COPI Mediated Transport Pathway Diagram
Golgi To ER Retrograde Transport Pathway antibodies	Golgi To ER Retrograde Transport Pathway Diagram
Membrane Trafficking Pathway antibodies	Membrane Trafficking Pathway Diagram

Diseases associated with anti-ARCN1 antibody

Disease Name	Pubmed Publications
Brain Diseases Antibodies	>1 publications with ARCN1 and Brain Diseases
Neoplasms Antibodies	>1 publications with ARCN1 and Neoplasms
Ataxia Antibodies	>1 publications with ARCN1 and Ataxia

Organs/Tissues associated with anti-ARCN1 antibody

Organ/Tissue Name	Pubmed Publications
Nerve Antibodies	>2 publications with ARCN1 and Nerve
Brain Antibodies	>2 publications with ARCN1 and Brain
Thyroid Antibodies	>1 publications with ARCN1 and Thyroid