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MOGAT3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643313

Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Also able to catalyze the terminal step in triacylglycerol synthesis by using diacylglycerol and fatty acyl-CoA as substrates. Has a preference toward palmitoyl-CoA and… More details

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Product Overview

Online Datasheet in PDF
Product Name
MOGAT3, Monoclonal Antibody
Full Product Name
MOGAT3 (2-acylglycerol O-acyltransferase 3, Acyl-CoA:monoacylglycerol Acyltransferase 3, MGAT3, Diacylglycerol O-acyltransferase Candidate 7, hDC7, Diacylglycerol Acyltransferase 2-like Protein 7, Monoacylglycerol O-acyltransferase 3, DC7, DGAT2L7, UNQ938
Product Gene Name
anti-MOGAT3 antibody
Product Synonym Names
Anti -MOGAT3 (2-acylglycerol O-acyltransferase 3, Acyl-CoA:monoacylglycerol Acyltransferase 3, MGAT3, Diacylglycerol O-acyltransferase Candidate 7, hDC7, Diacylglycerol Acyltransferase 2-like Protein 7, Monoacylglycerol O-acyltransferase 3, DC7, DGAT2L7, UNQ938
Immunogen Sequence
YLVWLYVDWD TPNQGGRRSE WIRNRAIWRQ LRDYYPVKLV KTAELPPDR*
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
3F7
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human MOGAT3.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
38,730 Da
Chromosome Location
Chromosome: 7; NC_000007.13 (100839010..100844302, complement). Location: 7q22.1
OMIM
610184
3D Structure
ModBase 3D Structure for Q86VF5
Immunogen
Partial recombinant protein corresponding to aa59-108 from human MOGAT3 (NP_835470) with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-MOGAT3 antibody

Antibodies; Abs to Enzymes; Acyltransferase
Applications Tested/Suitable for anti-MOGAT3 antibody
ELISA (EL/EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes for anti-MOGAT3 antibody
Suitable for use in Immunofluorescence, ELISA and Western Blot.
Dilution: Immunofluorescence: 10ug/ml
Sandwich ELISA: The detection limit is ~10ng/ml as a capture antibody

Western Blot (WB) of anti-MOGAT3 antibody

Western Blot detection against Immunogen (31.5kD).
Mouse Anti-MOGAT3 Monoclonal Antibody – Cat# MBS643313

Immunofluorescence (IF) of anti-MOGAT3 antibody

Immunofluorescence of monoclonal antibody to MOGAT3 on HeLa cell . [antibody concentration 10ug/ml].
Mouse Anti-MOGAT3 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS643313

Other Notes

Small volumes of anti-MOGAT3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MOGAT3 purchase

MBS643313 is an antibody targeting MOGAT3. Also known as MOGAT3 (2-acylglycerol O-acyltransferase 3, Acyl-CoA:monoacylglycerol Acyltransferase 3, MGAT3, Diacylglycerol O-acyltransferase Candidate 7, hDC7, Diacylglycerol Acyltransferase 2-like Protein 7, Monoacylglycerol O-acyltransferase 3, DC7, DGAT2L7, UNQ938. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for MOGAT3. It may not necessarily be applicable to this product.

NCBI GI #
71680832
NCBI GeneID
346606
NCBI Accession #
AAI00956.1
UniProt Primary Accession #
Q86VF5
UniProt Secondary Accession #
Q496A6; Q496A7; Q496A8; Q9UDW7
UniProt Related Accession #
Q86VF5
NCBI Official Full Name
MOGAT3 protein
NCBI Official Synonym Full Names
monoacylglycerol O-acyltransferase 3
NCBI Official Symbol
MOGAT3
NCBI Official Synonym Symbols
DC7; MGAT3; DGAT2L7
UniProt Protein Name
2-acylglycerol O-acyltransferase 3
UniProt Synonym Protein Names
Acyl-CoA:monoacylglycerol acyltransferase 3; MGAT3; Diacylglycerol O-acyltransferase candidate 7; hDC7; Diacylglycerol acyltransferase 2-like protein 7; Monoacylglycerol O-acyltransferase 3
Protein Family
2-acylglycerol O-acyltransferase
UniProt Gene Name
MOGAT3
UniProt Synonym Gene Names
DC7; DGAT2L7; MGAT3; hDC7
UniProt Entry Name
MOGT3_HUMAN
NCBI Protein Information
2-acylglycerol O-acyltransferase 3; hDC7; acyl-CoA:monoacylglycerol acyltransferase 3; diacylglycerol O-acyltransferase candidate 7; diacylglycerol acyltransferase 2-like protein 7; acyl coenzyme A:monoacylglycerol acyltransferase 3

NCBI Summary for MOGAT3

Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA (Cheng et al., 2003 [PubMed 12618427]).[supplied by OMIM, Mar 2008]

UniProt Comments for MOGAT3

MOGAT3: Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Also able to catalyze the terminal step in triacylglycerol synthesis by using diacylglycerol and fatty acyl-CoA as substrates. Has a preference toward palmitoyl-CoA and oleoyl-CoA. May be involved in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. Belongs to the diacylglycerol acyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; EC 2.3.1.22; Transferase; Membrane protein, integral; EC 2.3.1.20

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Molecular Function: 2-acylglycerol O-acyltransferase activity; diacylglycerol O-acyltransferase activity

Biological Process: glycerol metabolic process; triacylglycerol biosynthetic process
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Research Articles on MOGAT3

1. MGAT3 encodes a approximately 36-kDa transmembrane protein that is highly homologous to MGAT1 and -2 and is expressed in the human gastrointestinal tract with the highest level found in the ileum

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MOGAT3 antibody

 Reference Product  PubMed Publications
 DGAT1 antibody  >1 publications with MOGAT3 and DGAT1

Pathways associated with anti-MOGAT3 antibody

 Products by Pathway  Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Triacylglyceride Synthesis Pathway antibodies  Triacylglyceride Synthesis Pathway Diagram
 Triacylglycerol Biosynthesis Pathway antibodies  Triacylglycerol Biosynthesis Pathway Diagram
 Triacylglycerol Biosynthesis Pathway antibodies  Triacylglycerol Biosynthesis Pathway Diagram
 Triacylglycerol Biosynthesis Pathway antibodies  Triacylglycerol Biosynthesis Pathway Diagram

Diseases associated with anti-MOGAT3 antibody

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >1 publications with MOGAT3 and Liver Diseases
 Fatty Liver Antibodies  >1 publications with MOGAT3 and Fatty Liver
 Weight Loss Antibodies  >1 publications with MOGAT3 and Weight Loss

Organs/Tissues associated with anti-MOGAT3 antibody

 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >2 publications with MOGAT3 and Intestine
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