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TRAF3IP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643331

TRAF3IP1 play an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. More details

$895 / 0.2 mL +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
TRAF3IP1, Polyclonal Antibody
Full Product Name
TRAF3IP1, ID (TRAF3IP1, MIPT3, TRAF3-interacting protein 1, Interleukin-13 receptor alpha 1-binding protein 1, Microtubule-interacting protein associated with TRAF3)
Product Gene Name
anti-TRAF3IP1 antibody
Product Synonym Names
Anti -TRAF3IP1, ID (TRAF3IP1, MIPT3, TRAF3-interacting protein 1, Interleukin-13 receptor alpha 1-binding protein 1, Microtubule-interacting protein associated with TRAF3)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
78,632 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (239229185..239309541). Location: 2q37.3
OMIM
607380
3D Structure
ModBase 3D Structure for Q8TDR0
Immunogen
TRAF3IP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-423 amino acids from the Central region of human TRAF3IP1.

Product Categories/Family for anti-TRAF3IP1 antibody

Antibodies; Abs to Interleukin
Applications Tested/Suitable for anti-TRAF3IP1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-TRAF3IP1 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-TRAF3IP1 antibody

TRAF3IP1 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the TRAF3IP1 antibody detected the TRAF3IP1 protein (arrow).
Rabbit Anti-TRAF3IP1 Polyclonal Antibody – Cat# MBS643331

Other Notes

Small volumes of anti-TRAF3IP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRAF3IP1 purchase

MBS643331 is an antibody targeting TRAF3IP1. Also known as TRAF3IP1, ID (TRAF3IP1, MIPT3, TRAF3-interacting protein 1, Interleukin-13 receptor alpha 1-binding protein 1, Microtubule-interacting protein associated with TRAF3). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TRAF3IP1. It may not necessarily be applicable to this product.

NCBI GI #
37590616
NCBI GeneID
26146
NCBI Accession #
AAH59174.1
UniProt Primary Accession #
Q8TDR0
UniProt Secondary Accession #
Q6PCT1; Q7L8N9; Q9NRD6; Q9Y4Q1
UniProt Related Accession #
Q8TDR0
NCBI Official Full Name
TRAF3IP1 protein
NCBI Official Synonym Full Names
TNF receptor-associated factor 3 interacting protein 1
NCBI Official Symbol
TRAF3IP1
NCBI Official Synonym Symbols
MIPT3; MIP-T3
UniProt Protein Name
TRAF3-interacting protein 1
UniProt Synonym Protein Names
Interleukin-13 receptor alpha 1-binding protein 1; Microtubule-interacting protein associated with TRAF3
Protein Family
TRAF3-interacting protein
UniProt Gene Name
TRAF3IP1
UniProt Synonym Gene Names
MIPT3; MIP-T3
UniProt Entry Name
MIPT3_HUMAN
NCBI Protein Information
TRAF3-interacting protein 1; interleukin 13 receptor alpha 1-binding protein-1; interleukin-13 receptor alpha 1-binding protein 1; microtubule-interacting protein associated with TRAF3; microtubule interacting protein that associates with TRAF3; microtubule-interacting protein that associates with TRAF3

UniProt Comments for TRAF3IP1

TRAF3IP1: Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Belongs to the TRAF3IP1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Microtubule-binding

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: centrosome; axoneme; cilium

Molecular Function: protein binding; microtubule binding

Biological Process: organelle organization and biogenesis; neural tube patterning; intraflagellar transport; cilium biogenesis; embryonic heart tube development; embryonic digit morphogenesis; negative regulation of defense response to virus; embryonic camera-type eye development; negative regulation of interferon-beta production
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Research Articles on TRAF3IP1

1. MIP-T3 functions as a negative regulator of the innate type I interferon response by preventing TRAF3 from forming protein complexes with critical downstream transducers and effectors of antiviral response.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TRAF3IP1 antibody

 Reference Product  PubMed Publications
 TRAF3 antibody  >6 publications with TRAF3IP1 and TRAF3
 DISC1 antibody  >4 publications with TRAF3IP1 and DISC1

Diseases associated with anti-TRAF3IP1 antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >4 publications with TRAF3IP1 and Necrosis
 Neoplasms Antibodies  >1 publications with TRAF3IP1 and Neoplasms

Organs/Tissues associated with anti-TRAF3IP1 antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >2 publications with TRAF3IP1 and Nerve
 Kidney Antibodies  >2 publications with TRAF3IP1 and Kidney
 Eye Antibodies  >1 publications with TRAF3IP1 and Eye
 Brain Antibodies  >1 publications with TRAF3IP1 and Brain
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