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COG3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643369

The protein encoded by this gene has similarity to a yeast protein. It seems to be part of a peripheral membrane protein complex localized on cis/medial Golgi cisternae where it may participate in tethering intra-Golgi transport vesicles. [provided by RefSeq]. More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
COG3, Monoclonal Antibody
Full Product Name
COG3 (SEC34, Conserved Oligomeric Golgi Complex Subunit 3, COG Complex Subunit 3, Component of Oligomeric Golgi Complex 3, Vesicle-docking Protein SEC34 Homolog, p94)
Product Gene Name
Product Synonym Names
Anti -COG3 (SEC34, Conserved Oligomeric Golgi Complex Subunit 3, COG Complex Subunit 3, Component of Oligomeric Golgi Complex 3, Vesicle-docking Protein SEC34 Homolog, p94)
Immunogen Sequence
WDRRPDTTAP LTDRQTDSVL ELKAAAENLP VPAELPIEDL CSLTSQSLPI ELTSVVPEST EDILLKGFTS LGMEEERIET AQQFFSWFAK LQTQMDQDEG
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
2G7
Host
Mouse
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human COG3. Species Crossreactivity: mouse.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
94,096 Da
Chromosome Location
Chromosome: 13; NC_000013.10 (46039030..46110833). Location: 13q14.13
OMIM
606975
3D Structure
ModBase 3D Structure for Q96JB2
Immunogen
Partial recombinant corresponding to aa25-125 from human COG3 (NP_113619) with GST tag. MW of the GST tag alone is 26kD.
Applications Tested/Suitable for anti-COG3 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-COG3 antibody
Suitable for use in ELISA and Western Blot.

Western Blot (WB) of anti-COG3 antibody

Western Blot detection against Immunogen (37.11kD).
Mouse Anti-COG3 Monoclonal Antibody – Cat# MBS643369

Western Blot (WB) of anti-COG3 antibody

COG3 monoclonal antibody. Western Blot analysis of COG3 expression in Raw 264.7.
Mouse Anti-COG3 Monoclonal Antibody, Western Blot (WB) – Cat# MBS643369

Testing Data of anti-COG3 antibody

Detection limit for recombinant GST tagged COG3 is 0.03ng/ml as a capture antibody.
Mouse Anti-COG3 Monoclonal Antibody, Testing Data – Cat# MBS643369

Other Notes

Small volumes of anti-COG3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for COG3 purchase

MBS643369 is an antibody targeting COG3. Also known as COG3 (SEC34, Conserved Oligomeric Golgi Complex Subunit 3, COG Complex Subunit 3, Component of Oligomeric Golgi Complex 3, Vesicle-docking Protein SEC34 Homolog, p94). Reactive in Human, Mouse. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for COG3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
COG3 protein
NCBI Official Synonym Full Names
component of oligomeric golgi complex 3
NCBI Official Symbol
COG3
NCBI Official Synonym Symbols
SEC34
UniProt Protein Name
Conserved oligomeric Golgi complex subunit 3
UniProt Synonym Protein Names
Component of oligomeric Golgi complex 3; Vesicle-docking protein SEC34 homolog; p94
UniProt Gene Name
COG3
UniProt Synonym Gene Names
SEC34; COG complex subunit 3
UniProt Entry Name
COG3_HUMAN
NCBI Protein Information
conserved oligomeric Golgi complex subunit 3; p94; COG complex subunit 3; tethering factor SEC34; vesicle-docking protein SEC34 homolog

NCBI Summary for COG3

This gene encodes a component of the conserved oligomeric Golgi (COG) complex which is composed of eight different subunits and is required for normal Golgi morphology and localization. Defects in the COG complex result in multiple deficiencies in protein glycosylation. The protein encoded by this gene is involved in ER-Golgi transport.[provided by RefSeq, Jun 2011]
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UniProt Comments for COG3

COG3: Involved in ER-Golgi transport. Belongs to the COG3 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Vesicle

Chromosomal Location of Human Ortholog: 13q14.13

Cellular Component: nucleoplasm; Golgi apparatus; cis-Golgi network; cytoplasm; plasma membrane; Golgi transport complex

Molecular Function: protein binding; protein transporter activity

Biological Process: intracellular protein transport; intra-Golgi vesicle-mediated transport; retrograde transport, vesicle recycling within Golgi; ER to Golgi vesicle-mediated transport; protein stabilization; protein localization in organelle; retrograde vesicle-mediated transport, Golgi to ER; protein amino acid glycosylation; Golgi organization and biogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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