Rabbit Anti-SSH2 Polyclonal Antibody – Cat# MBS643441

Western Blot analysis of SSH2 expression in transfected 293T cell line by SSH2 polyclonal antibody. Lane 1: SSH2 transfected lysate (19.9kD). Lane 2: Non-transfected lysate.

SSH2 Antibody – Rabbit Polyclonal

Name: SSH2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS643441
Price: 970 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643441

MBS643441 is an antibody targeting SSH2. Also known as SSH2 (Protein Phosphatase Slingshot Homolog 2, SSH-like Protein 2, SSH2L, SSH-2L, hSSH-2L, KIAA1725). Reactive in Human. Host: Rabbit. More details

$970 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SSH2, Polyclonal Antibody

Full Product Name

SSH2 (Protein Phosphatase Slingshot Homolog 2, SSH-like Protein 2, SSH2L, SSH-2L, hSSH-2L, KIAA1725)

Product Gene Name

anti-SSH2 antibody

Product Synonym Names

Anti -SSH2 (Protein Phosphatase Slingshot Homolog 2, SSH-like Protein 2, SSH2L, SSH-2L, hSSH-2L, KIAA1725)

Immunogen Sequence

MIPYFSANAV ISQNAINQLI SESFLTVKGA ALFLPRGNGS STPRISHRRN KHAGDLQQHL QAMFILLRPE DNIRLAVRLE STYQNRTRYM VVVSTNGRQD TEESIVLGMD FSSNDSSTCT MGLVLPLWSD TLIHLDGDGG FSVSTDNRVH IFKPVSVQAM WVDRDSRNKH CDVLLVEE

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human SSH2.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

158,216 Da

Chromosome Location

Chromosome: 17; NC_000017.10 (27952956..28257231, complement). Location: 17q11.2

OMIM

606779

3D Structure

ModBase 3D Structure for Q76I76

Immunogen

Full length human SSH2, aa1-178 (AAH11636.2).

Product Categories/Family for anti-SSH2 antibody

Antibodies; Abs to Enzymes; Phosphatase

Applications Tested/Suitable for anti-SSH2 antibody

Western Blot (WB)

Application Notes for anti-SSH2 antibody

Suitable for use in Western Blot.

Other Notes

Small volumes of anti-SSH2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SSH2. It may not necessarily be applicable to this product.

NCBI GI #

45829588

NCBI GeneID

85464

NCBI Accession #

AAH68223.1

UniProt Primary Accession #

Q76I76

UniProt Secondary Accession #

Q8TDB5; Q8WYL1; Q8WYL2; Q96F40; Q96H36; Q9C0D8

UniProt Related Accession #

Q76I76

NCBI Official Full Name

SSH2 protein

NCBI Official Synonym Full Names

slingshot protein phosphatase 2

NCBI Official Symbol

SSH2

NCBI Official Synonym Symbols

SSH-2; SSH-2L

UniProt Protein Name

Protein phosphatase Slingshot homolog 2

UniProt Synonym Protein Names

SSH-like protein 2

Protein Family

Protein phosphatase Slingshot

UniProt Gene Name

SSH2

UniProt Synonym Gene Names

KIAA1725; SSH2L; SSH-2L; hSSH-2L

UniProt Entry Name

SSH2_HUMAN

NCBI Protein Information

protein phosphatase Slingshot homolog 2; SSH-like protein 2

NCBI Summary for SSH2

This gene encodes a protein tyrosine phosphatase that plays a key role in the regulation of actin filaments. The encoded protein dephosphorylates and activates cofilin, which promotes actin filament depolymerization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

UniProt Comments for SSH2

SSH2: Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein. Belongs to the protein-tyrosine phosphatase family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.3.48; Actin-binding; Protein phosphatase, dual-specificity; EC 3.1.3.16

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: extracellular space; cytoskeleton; cytoplasm

Molecular Function: DNA binding; protein tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity; actin binding; phosphoprotein phosphatase activity

Biological Process: regulation of actin polymerization and/or depolymerization; protein amino acid dephosphorylation; regulation of axonogenesis; actin cytoskeleton organization and biogenesis

Research Articles on SSH2

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SSH2 antibody

Reference Product	PubMed Publications
LIMK1 antibody	>2 publications with SSH2 and LIMK1

Pathways associated with anti-SSH2 antibody

Products by Pathway	Pathway Diagram
Regulation Of Actin Cytoskeleton Pathway antibodies	Regulation Of Actin Cytoskeleton Pathway Diagram
Regulation Of Actin Cytoskeleton Pathway antibodies	Regulation Of Actin Cytoskeleton Pathway Diagram
Regulation Of Actin Cytoskeleton Pathway antibodies	Regulation Of Actin Cytoskeleton Pathway Diagram

Diseases associated with anti-SSH2 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>2 publications with SSH2 and Neoplasms
Liver Neoplasms Antibodies	>1 publications with SSH2 and Liver Neoplasms
Carcinoma, Hepatocellular Antibodies	>1 publications with SSH2 and Carcinoma, Hepatocellular
Death Antibodies	>1 publications with SSH2 and Death
Liver Diseases Antibodies	>1 publications with SSH2 and Liver Diseases

Organs/Tissues associated with anti-SSH2 antibody

Organ/Tissue Name	Pubmed Publications
Ascites Antibodies	>1 publications with SSH2 and Ascites
Muscle Antibodies	>1 publications with SSH2 and Muscle
Stomach Antibodies	>1 publications with SSH2 and Stomach
Lung Antibodies	>1 publications with SSH2 and Lung
Thyroid Antibodies	>1 publications with SSH2 and Thyroid