Rat Anti-IL17D Monoclonal Antibody – Cat# MBS643453

Detection of IL-17D in mouse splenocytes by Flow Cytometry. Mouse splenocytes were stained with MBS643453 (filled histogram) or isotype control antibody|(open histogram).

Interleukin 17d (IL17D) Antibody – Rat Monoclonal

Name: IL17D Antibody; Monoclonal; Rat; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS643453
Price: 1045 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643453

The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit… More details

$1045 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Interleukin 17D (IL17D), Monoclonal Antibody

Full Product Name

Interleukin 17D (IL-17D)

Product Gene Name

anti-IL17D antibody

Product Synonym Names

Anti -Interleukin 17D (IL-17D)

Clonality

Monoclonal

Isotype

IgG2a

Clone Number

8H142

Host

Rat

Species Reactivity

Mouse

Form/Format

Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.

Purity/Purification

Affinity Purified
Purified by Protein G affinity chromatography.

Specificity

Recognizes mouse Interleukin 17D). Does not crossreact with recombinant human IL-17D or recombinant mouse IL-17, IL-17B, IL-17C, IL-17E or IL-17F.

Preparation and Storage

Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

21,893 Da

Chromosome Location

Chromosome: 13; NC_000013.10 (21276222..21297239). Location: 13q11

OMIM

607587

3D Structure

ModBase 3D Structure for Q8TAD2

Immunogen

Recombinant protein corresponding to aa25-205 from mouse Interleukin 17D expressed in E. coli (NP_665836).

Product Categories/Family for anti-IL17D antibody

Antibodies; Abs to Interleukin

Applications Tested/Suitable for anti-IL17D antibody

ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)

Application Notes for anti-IL17D antibody

Suitable for use in Direct ELISA, Western Blot and Flow Cytometry.
Dilution: Western Blot: 1ug/ml using recombinant mouse 17D
Flow Cytometry: 2.5ug stains 10e6 cells using mouse splenocytes fixed with paraformaldehyde and permeabilized with saponin.

Other Notes

Small volumes of anti-IL17D antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL17D purchase

MBS643453 is an antibody targeting IL17D. Also known as Interleukin 17D (IL-17D). Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for IL17D. It may not necessarily be applicable to this product.

NCBI GI #

19923715

NCBI GeneID

53342

NCBI Accession #

NP_612141.1

UniProt Primary Accession #

Q8TAD2

UniProt Secondary Accession #

B1AM69

UniProt Related Accession #

Q8TAD2

GenBank Nucleotide #

NM_138284.1

NCBI Official Full Name

interleukin-17D

NCBI Official Synonym Full Names

interleukin 17D

NCBI Official Symbol

IL17D

NCBI Official Synonym Symbols

IL27; IL-22; IL-27; IL-17D

UniProt Protein Name

Interleukin-17D

UniProt Synonym Protein Names

Interleukin-27

Protein Family

Interleukin

UniProt Gene Name

IL17D

UniProt Synonym Gene Names

IL27; IL-17D; IL-27

UniProt Entry Name

IL17D_HUMAN

NCBI Protein Information

interleukin-17D; interleukin 27; interleukin-27

NCBI Summary for IL17D

The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent. [provided by RefSeq, Jul 2008]

UniProt Comments for IL17D

IL17D: Induces expression of IL-6, IL-8, and GM-CSF from endothelial cells. Belongs to the IL-17 family.

Protein type: Secreted; Cytokine; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 13q11

Cellular Component: extracellular space

Molecular Function: cytokine activity

Biological Process: inflammatory response

Research Articles on IL17D

1. These experiments were designed to investigate the effects of IL-17 upon the phenotype and function of human Natural Killer (NK) cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IL17D antibody

Reference Product	PubMed Publications
IL6 antibody	>1 publications with IL17D and IL6

Diseases associated with anti-IL17D antibody

Disease Name	Pubmed Publications
Necrosis Antibodies	>2 publications with IL17D and Necrosis
Inflammation Antibodies	>2 publications with IL17D and Inflammation

Organs/Tissues associated with anti-IL17D antibody

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>2 publications with IL17D and Bone
Heart Antibodies	>1 publications with IL17D and Heart
Muscle Antibodies	>1 publications with IL17D and Muscle
Embryonic Tissue Antibodies	>1 publications with IL17D and Embryonic Tissue
Skin Antibodies	>1 publications with IL17D and Skin
Lung Antibodies	>1 publications with IL17D and Lung
Pancreas Antibodies	>1 publications with IL17D and Pancreas
Brain Antibodies	>1 publications with IL17D and Brain