Rabbit Anti-PADI6 Polyclonal Antibody – Cat# MBS643484

Western Blot analysis in mouse stomach tissue lysates (35ug/lane) using MBS643484. This demonstrates MBS643484 detected the PADI6 protein (arrow).

PADI6 Antibody – Rabbit Polyclonal

Name: PADI6 Antibody; Polyclonal; Rabbit; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS643484
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643484

Peptidylarginine deiminases (PADs, EC 3.5.3.15), including PADI6, make up a family of posttranslational protein modification enzymes that convert arginine residues to citrulline residues in the presence of calcium ions. More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PADI6, Polyclonal Antibody

Full Product Name

PADI6, NT (PADI6, Protein-arginine deiminase type-6, Peptidylarginine deiminase VI, Protein-arginine deiminase type VI)

Product Gene Name

anti-PADI6 antibody

Product Synonym Names

Anti -PADI6, NT (PADI6, Protein-arginine deiminase type-6, Peptidylarginine deiminase VI, Protein-arginine deiminase type VI)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human, mouse

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

77,727 Da

Chromosome Location

Chromosome: 1; NC_000001.10 (17698741..17728195). Location: 1p36.13

OMIM

610363

3D Structure

ModBase 3D Structure for Q6TGC4

Immunogen

PADI6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-215 amino acids from the N-terminal region of human PADI6.

Product Categories/Family for anti-PADI6 antibody

Antibodies; Abs to Enzymes

Applications Tested/Suitable for anti-PADI6 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-PADI6 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-PADI6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PADI6 purchase

MBS643484 is an antibody targeting PADI6. Also known as PADI6, NT (PADI6, Protein-arginine deiminase type-6, Peptidylarginine deiminase VI, Protein-arginine deiminase type VI). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PADI6. It may not necessarily be applicable to this product.

NCBI GI #

117414158

NCBI GeneID

353238

NCBI Accession #

NP_997304.3

UniProt Primary Accession #

Q6TGC4

UniProt Secondary Accession #

Q330K5; Q70SX3

UniProt Related Accession #

Q6TGC4

GenBank Nucleotide #

NM_207421.3

NCBI Official Full Name

protein-arginine deiminase type-6

NCBI Official Synonym Full Names

peptidyl arginine deiminase, type VI

NCBI Official Symbol

PADI6

NCBI Official Synonym Symbols

hPADVI

UniProt Protein Name

Protein-arginine deiminase type-6

UniProt Synonym Protein Names

Peptidyl arginine deiminase-like protein; Peptidylarginine deiminase VI; hPADVI; Protein-arginine deiminase type VI

Protein Family

Protein-arginine deiminase

UniProt Gene Name

PADI6

UniProt Synonym Gene Names

hPADVI

UniProt Entry Name

PADI6_HUMAN

NCBI Protein Information

protein-arginine deiminase type-6; peptidylarginine deiminase type 6; peptidyl arginine deiminase-like protein

NCBI Summary for PADI6

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. This protein may play a role in cytoskeletal reorganization in the egg and in early embryo development. [provided by RefSeq, Sep 2012]

UniProt Comments for PADI6

PADI6: Catalyzes the deimination of arginine residues of proteins. May be involved in cytoskeletal reorganization in the egg and early embryo. Belongs to the protein arginine deiminase family.

Protein type: EC 3.5.3.15; Cytoskeletal; Hydrolase

Chromosomal Location of Human Ortholog: 1p36.13

Cellular Component: intermediate filament cytoskeleton; cytoplasm; nucleus

Molecular Function: calcium ion binding; protein-arginine deiminase activity

Biological Process: translational machinery localization; cytoplasm organization and biogenesis; cytoskeleton organization and biogenesis; peptidyl-citrulline biosynthetic process from peptidyl-arginine

Research Articles on PADI6

1. Crystallographic determination of 14-3-3-sigma binding sites in the human peptidylarginine deiminase type VI.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PADI6 antibody

Reference Product	PubMed Publications
NPM2 antibody	>1 publications with PADI6 and NPM2
NLRP5 antibody	>1 publications with PADI6 and NLRP5
OOEP antibody	>1 publications with PADI6 and OOEP

Pathways associated with anti-PADI6 antibody

Products by Pathway	Pathway Diagram
Protein Citrullination Pathway antibodies	Protein Citrullination Pathway Diagram
Protein Citrullination Pathway antibodies	Protein Citrullination Pathway Diagram

Diseases associated with anti-PADI6 antibody

Disease Name	Pubmed Publications
Immune System Diseases Antibodies	>2 publications with PADI6 and Immune System Diseases
Inflammation Antibodies	>1 publications with PADI6 and Inflammation
Neoplasms Antibodies	>1 publications with PADI6 and Neoplasms

Organs/Tissues associated with anti-PADI6 antibody

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>1 publications with PADI6 and Skin