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EPB41L3 Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643513

MBS643513 is an antibody targeting EPB41L3. Also known as EPB41L3 (Band 4.1-like Protein 3, 4.1B, Differentially Expressed in Adenocarcinoma of the Lung Protein 1, DAL-1, DAL1, KIAA0987, FLJ37633). Reactive in Human. Host: Mouse. Critical growth regulator in… More details

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Product Overview

Online Datasheet in PDF
Product Name
EPB41L3, Polyclonal Antibody
Full Product Name
EPB41L3 (Band 4.1-like Protein 3, 4.1B, Differentially Expressed in Adenocarcinoma of the Lung Protein 1, DAL-1, DAL1, KIAA0987, FLJ37633)
Product Gene Name
anti-EPB41L3 antibody
Product Synonym Names
Anti -EPB41L3 (Band 4.1-like Protein 3, 4.1B, Differentially Expressed in Adenocarcinoma of the Lung Protein 1, DAL-1, DAL1, KIAA0987, FLJ37633)
Immunogen Sequence
MTTESGSDSE SKPDQEAEPQ EAAGAQGRAG APVPEPPKEE QQQALEQFAA AAAHSTPVRR EVTDKEQEFA ARAAKQLEYQ QLEDDKLSQK SSSSKLSRSP LKIVKKPKSM QCKVILLDGS EYTCDVEKRS RGQVLFDKVC EHLNLLEKDY FGLTYRDAEN QKNWLDPAKE IKKQVRSGAW HFSFNVKFYP PDPAQLSEDI TRYYLCLQLR DDIVSGRLPC SFVTLALLGS YTVQSELGDY DPDECGSDYI SEFRFAPNHT KELEDKVIEL HKSHRGMTPA EAEMHFLENA KKLSMYGVDL HHAKDSEGVE IMLGVCASGL LIYRDRLRIN RFAWPKVLKI SYKRNNFYIK IRPGEFEQFE STIGFKLPNH RAAKRLWKVC VEHHTFFRLL LPEAPPKKFL TLGSKFRYSG RTQAQTRRAS ALIDRPAPYF ERSSSKRYTM SRSLDGASVN ENHEIYMKDS MSAAEVGTGQ YATTKGISQT NLITTVTPEK KAEEERDEEE DKRRKGEEVT PISAIRHEGK TDSERTDTAA DGETTATEEL EKTQDDLMKH QTNISELKRT FLETSTDTAV TNEWEKRLST SPVRLAARQE DAPMIEPLVP EEKMETKTES SGIETEPTVH HLPLSTEKVV QETVLVEERR VVHASGDASY SAGDSGDAAA QPAFTGIKGK EGSALTEGAK EEGGEEVAKA VLEQEETAAA SRERQEEQSA AIHISETLEQ KPHFESSTVK TETISFGSVS PGGVKLEIST KEVPVVHTET KTITYESSQV DPGTDLEPGV LMSAQTITSE TTSTTTTTHI TKTVKGGISE TRIEKRIVIT GDADIDHDQA LAQAIKEAKE QHPDMSVTKV VVHKETEITP EDGED
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.4.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human EPB41L3.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Chromosome Location
Chromosome: 18; NC_000018.9 (5392380..5630662, complement). Location: 18p11.32
OMIM
605331
3D Structure
ModBase 3D Structure for Q9Y2J2
Immunogen
Full length recombinant protein corresponding to aa1-865 of human EPB41L3

Product Categories/Family for anti-EPB41L3 antibody

Antibodies; Abs to Membrane Proteins
Applications Tested/Suitable for anti-EPB41L3 antibody
Western Blot (WB)
Application Notes for anti-EPB41L3 antibody
Optimal dilutions should be determined by the researcher

Western Blot (WB) of anti-EPB41L3 antibody

Western Blot analysis of EPB41L3 expression in transfected 293T cell line by EPB41L3 polyclonal antibody. Lane 1: EPB41L3 transfected lysate (95.15kD). Lane 2: Non-transfected lysate.
Mouse Anti-EPB41L3 Polyclonal Antibody – Cat# MBS643513

Other Notes

Small volumes of anti-EPB41L3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EPB41L3. It may not necessarily be applicable to this product.

NCBI GI #
13544009
NCBI GeneID
23136
NCBI Accession #
AAH06141.1
UniProt Primary Accession #
Q9Y2J2
UniProt Secondary Accession #
O95713; Q9BRP5
UniProt Related Accession #
Q9Y2J2
NCBI Official Full Name
EPB41L3 protein
NCBI Official Synonym Full Names
erythrocyte membrane protein band 4.1-like 3
NCBI Official Symbol
EPB41L3
NCBI Official Synonym Symbols
4.1B; DAL1; DAL-1
UniProt Protein Name
Band 4.1-like protein 3
UniProt Synonym Protein Names
4.1B; Differentially expressed in adenocarcinoma of the lung protein 1
Protein Family
Band 4.1-like protein
UniProt Gene Name
EPB41L3
UniProt Synonym Gene Names
DAL1; KIAA0987; DAL-1
UniProt Entry Name
E41L3_HUMAN
NCBI Protein Information
band 4.1-like protein 3; differentially expressed in adenocarcinoma of the lung protein 1

UniProt Comments for EPB41L3

EPB41L3: a possible tumor suppressor protein that plays a role in cell adhesion and apoptosis. Critical growth regulator in the pathogenesis of meningiomas. Three alternatively spliced isoforms have been described.

Protein type: Tumor suppressor; Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 18p11.32

Cellular Component: extrinsic to membrane; cytoskeleton; paranode region of axon; cytoplasm; plasma membrane; axolemma; intercellular junction

Molecular Function: protein binding; structural constituent of cytoskeleton; actin binding

Biological Process: regulation of cell shape; cytoskeletal anchoring; apoptosis; myelin maintenance; cortical cytoskeleton organization and biogenesis; cortical actin cytoskeleton organization and biogenesis; neurite morphogenesis; paranodal junction assembly
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Research Articles on EPB41L3

1. aberrant CADM1 and 4.1B expression is involved in progression of breast cancer, especially in invasion into the stroma and metastasis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-EPB41L3 antibody

 Reference Product  PubMed Publications
 CADM1 antibody  >8 publications with EPB41L3 and CADM1
 TJP2 antibody  >1 publications with EPB41L3 and TJP2

Pathways associated with anti-EPB41L3 antibody

 Products by Pathway  Pathway Diagram
 Tight Junction Pathway antibodies  Tight Junction Pathway Diagram
 Tight Junction Pathway antibodies  Tight Junction Pathway Diagram

Diseases associated with anti-EPB41L3 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >42 publications with EPB41L3 and Neoplasms
 Lung Neoplasms Antibodies  >22 publications with EPB41L3 and Lung Neoplasms
 Carcinoma Antibodies  >20 publications with EPB41L3 and Carcinoma
 Lung Diseases Antibodies  >13 publications with EPB41L3 and Lung Diseases
 Breast Neoplasms Antibodies  >10 publications with EPB41L3 and Breast Neoplasms
 Death Antibodies  >4 publications with EPB41L3 and Death
 Brain Diseases Antibodies  >3 publications with EPB41L3 and Brain Diseases
 Carcinoma, Squamous Cell Antibodies  >2 publications with EPB41L3 and Carcinoma, Squamous Cell
 Uterine Cervical Neoplasms Antibodies  >2 publications with EPB41L3 and Uterine Cervical Neoplasms
 Neoplasms, Experimental Antibodies  >1 publications with EPB41L3 and Neoplasms, Experimental

Organs/Tissues associated with anti-EPB41L3 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >27 publications with EPB41L3 and Lung
 Brain Antibodies  >17 publications with EPB41L3 and Brain
 Kidney Antibodies  >6 publications with EPB41L3 and Kidney
 Nerve Antibodies  >4 publications with EPB41L3 and Nerve
 Prostate Antibodies  >4 publications with EPB41L3 and Prostate
 Spinal Cord Antibodies  >3 publications with EPB41L3 and Spinal Cord
 Muscle Antibodies  >2 publications with EPB41L3 and Muscle
 Intestine Antibodies  >2 publications with EPB41L3 and Intestine
 Heart Antibodies  >2 publications with EPB41L3 and Heart
 Testis Antibodies  >2 publications with EPB41L3 and Testis
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