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PLA2G15 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643530

Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This enzyme is present in… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LYPLA3 (PLA2G15), Polyclonal Antibody
Full Product Name
LYPLA3 (PLA2G15, Group XV Phospholipase A2, 1-O-acylceramide Synthase, ACS, LCAT-like Lysophospholipase, LLPL, Lysophospholipase 3, Lysosomal Phospholipase A2, LPLA2, UNQ341/PRO540)
Product Gene Name
Product Synonym Names
Anti -LYPLA3 (PLA2G15, Group XV Phospholipase A2, 1-O-acylceramide Synthase, ACS, LCAT-like Lysophospholipase, LLPL, Lysophospholipase 3, Lysosomal Phospholipase A2, LPLA2, UNQ341/PRO540)
Immunogen Sequence
MGLHLRPYRV GLLPDGLLFL LLLLMLLADP ALPAGRHPPV VLVPGDLGNQ LEAKLDKPTV VHYLCSKKTE SYFTIWLNLE LLLPVIIDCW IDNIRLVYNK TSRATQFPDG VDVRVPGFGK TFSLEFLDPS KSSVGSYFHT MVESLVGWGY TRGEDVRGAP YDWRRAPNEN GPYFLALREM IEEMYQLYGG PVVLVAHSMG NMYTLYFLQR QPQAWKDKYI RAFVSLGAPW GGVAKTLRVL ASGDNNRIPV IGPLKIREQQ RSAVSTSWLL PYNYTWSPEK VFVQTPTINY TLRDYRKFFQ DIGFEDGWLM RQDTEGLVEA TMPPGVQLHC LYGTGVPTPD SFYYESFPDR DPKICFGDGD GTVNLKSALQ CQAWQSRQEH QVLLQELPGS EHIEMLANAT TLAYLKRVLL GP
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid.
Purity/Purification
Serum
Serum
Specificity
Recognizes human PLA2G15.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
46,658 Da
Chromosome Location
Chromosome: 16; NC_000016.9 (68279240..68294965). Location: 16q22.1
OMIM
609362
3D Structure
ModBase 3D Structure for Q8NCC3
Immunogen
Full length human PLA2G15, aa1-412 (NP_036452.1).
Applications Tested/Suitable for anti-PLA2G15 antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-PLA2G15 antibody
Suitable for use in Western Blot and Immunoprecipitation.

Western Blot (WB) of anti-PLA2G15 antibody

Western Blot analysis of PLA2G15 expression in transfected 293T cell line using MBS643530. Lane 1: PLA2G15 transfected lysate (46.7kD). Lane 2: Non-transfected lysate.
Rabbit Anti-PLA2G15 Polyclonal Antibody – Cat# MBS643530

Immunoprecipitation (IP) of anti-PLA2G15 antibody

Immunoprecipitation of PLA2G15 transfected lysate using using MBS643530 and Protein A Magnetic Bead, and immunoblotted with PLA2G15 purified mouse polyclonal antibody.
Rabbit Anti-PLA2G15 Polyclonal Antibody, Immunoprecipitation (IP) – Cat# MBS643530

Other Notes

Small volumes of anti-PLA2G15 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLA2G15 purchase

MBS643530 is an antibody targeting PLA2G15. Also known as LYPLA3 (PLA2G15, Group XV Phospholipase A2, 1-O-acylceramide Synthase, ACS, LCAT-like Lysophospholipase, LLPL, Lysophospholipase 3, Lysosomal Phospholipase A2, LPLA2, UNQ341/PRO540). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PLA2G15. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
lysophospholipase 3 (lysosomal phospholipase A2), isoform CRA_b
NCBI Official Synonym Full Names
phospholipase A2, group XV
NCBI Official Symbol
PLA2G15
NCBI Official Synonym Symbols
ACS; LLPL; LPLA2; LYPLA3; GXVPLA2
UniProt Protein Name
Group XV phospholipase A2
UniProt Synonym Protein Names
1-O-acylceramide synthase; ACS; LCAT-like lysophospholipase; LLPL; Lysophospholipase 3; Lysosomal phospholipase A2
UniProt Gene Name
PLA2G15
UniProt Synonym Gene Names
LYPLA3; ACS; LLPL; LPLA2
UniProt Entry Name
PAG15_HUMAN
NCBI Protein Information
group XV phospholipase A2; 1-O-acylceramide synthase; lysosomal phospholipase A2; LCAT-like lysophospholipase; lysophospholipase 3 (lysosomal phospholipase A2)

UniProt Comments for PLA2G15

LYPLA3: Has transacylase and calcium-independent phospholipase A2 activity. Catalyzes the formation of 1-O-acyl-N- acetylsphingosine and the concomitant release of a lyso- phospholipid. May have weak lysophospholipase activity. Belongs to the AB hydrolase superfamily. Lipase family.

Protein type: Transferase; Secreted; Phospholipase; Secreted, signal peptide; Lipid Metabolism - glycerophospholipid; EC 2.3.1.-

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: mitochondrion; lysosome

Molecular Function: calcium-independent phospholipase A2 activity; phospholipid binding; O-acyltransferase activity; lysophospholipase activity

Biological Process: fatty acid catabolic process; ceramide metabolic process; phosphatidylcholine metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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