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SLC6A14 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643590

This gene encodes a member of the solute carrier family 6. Members of this family are sodium and chloride dependent neurotransmitter transporters. The encoded protein transports both neutral and cationic amino acids. This protein may also function as a… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SLC6A14, Polyclonal Antibody
Full Product Name
SLC6A14, CT (SLC6A14, Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+), Amino acid transporter ATB0+, Solute carrier family 6 member 14)
Product Gene Name
anti-SLC6A14 antibody
Product Synonym Names
Anti -SLC6A14, CT (SLC6A14, Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+), Amino acid transporter ATB0+, Solute carrier family 6 member 14)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
72,153 Da
Chromosome Location
Chromosome: X; NC_000023.10 (115567747..115592625). Location: Xq23
OMIM
300444
3D Structure
ModBase 3D Structure for Q9UN76
Immunogen
SLC6A14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 601-631 amino acids from the C-terminal region of human SLC6A14.

Product Categories/Family for anti-SLC6A14 antibody

Antibodies; Abs to Ion Channel
Applications Tested/Suitable for anti-SLC6A14 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-SLC6A14 antibody
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50

Western Blot (WB) of anti-SLC6A14 antibody

Western Blot analysis in HL-60 cell line lysates (35ug/lane) using MBS643590. This demonstrates MBS643590 detected the SLC6A14 protein (arrow).
Rabbit Anti-SLC6A14 Polyclonal Antibody – Cat# MBS643590

Immunohistochemistry (IHC) of anti-SLC6A14 antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human esophageal carcinoma using 042972 followed by peroxidase conjugation of the secondary antibody and DAB staining.
Rabbit Anti-SLC6A14 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS643590

Other Notes

Small volumes of anti-SLC6A14 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLC6A14 purchase

MBS643590 is an antibody targeting SLC6A14. Also known as SLC6A14, CT (SLC6A14, Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+), Amino acid transporter ATB0+, Solute carrier family 6 member 14). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC6A14. It may not necessarily be applicable to this product.

NCBI GI #
6005715
NCBI GeneID
11254
NCBI Accession #
NP_009162.1
UniProt Primary Accession #
Q9UN76
UniProt Secondary Accession #
Q5H942
UniProt Related Accession #
Q9UN76
GenBank Nucleotide #
NM_007231.4
NCBI Official Full Name
sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)
NCBI Official Synonym Full Names
solute carrier family 6 (amino acid transporter), member 14
NCBI Official Symbol
SLC6A14
NCBI Official Synonym Symbols
BMIQ11
UniProt Protein Name
Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)
UniProt Synonym Protein Names
Amino acid transporter ATB0+; Solute carrier family 6 member 14
Protein Family
Sodium- and chloride-dependent neutral and basic amino acid transporter
UniProt Gene Name
SLC6A14
UniProt Entry Name
S6A14_HUMAN
NCBI Protein Information
sodium- and chloride-dependent neutral and basic amino acid transporter B(0+); sodium- and chloride-dependent neutral and basic amino acid transporter B(0+); amino acid transporter B0+; amino acid transporter ATB0+; solute carrier family 6 (neurotransmitter transporter), member 14

UniProt Comments for SLC6A14

SLC6A14: Mediates the uptake of a broad range of neutral and cationic amino acids (with the exception of proline) in a Na(+)/Cl(-)-dependent manner. Genetic variations in SLC6A14 may be associated with obesity in some populations, as shown by significant differences in allele frequencies between obese and non-obese individuals. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A14 subfamily.

Protein type: Transporter; Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq23

Cellular Component: brush border membrane; integral to membrane; plasma membrane; vesicle

Molecular Function: neurotransmitter:sodium symporter activity; amino acid transmembrane transporter activity

Biological Process: amino acid metabolic process; amino acid transport; neurotransmitter transport; transport; response to toxin; ion transport; transmembrane transport

Disease: Body Mass Index Quantitative Trait Locus 11
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Research Articles on SLC6A14

1. Single nucleotide polymorphism in SLC6A14 gene is associated with cystic fibrosis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLC6A14 antibody

 Reference Product  PubMed Publications
 SLC23A1 antibody  >1 publications with SLC6A14 and SLC23A1

Pathways associated with anti-SLC6A14 antibody

 Products by Pathway  Pathway Diagram
 Amino Acid Transport Across The Plasma Membrane Pathway antibodies  Amino Acid Transport Across The Plasma Membrane Pathway Diagram
 Na+/Cl- Dependent Neurotransmitter Transporters Pathway antibodies  Na+/Cl- Dependent Neurotransmitter Transporters Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway antibodies  Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway Diagram
 Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway antibodies  Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway Diagram

Diseases associated with anti-SLC6A14 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >5 publications with SLC6A14 and Neoplasms
 Insulin Resistance Antibodies  >1 publications with SLC6A14 and Insulin Resistance
 Adenocarcinoma Antibodies  >1 publications with SLC6A14 and Adenocarcinoma
 Uterine Cervical Neoplasms Antibodies  >1 publications with SLC6A14 and Uterine Cervical Neoplasms
 Breast Neoplasms Antibodies  >1 publications with SLC6A14 and Breast Neoplasms
 Infertility, Male Antibodies  >1 publications with SLC6A14 and Infertility, Male
 Uterine Neoplasms Antibodies  >1 publications with SLC6A14 and Uterine Neoplasms
 Liver Neoplasms Antibodies  >1 publications with SLC6A14 and Liver Neoplasms

Organs/Tissues associated with anti-SLC6A14 antibody

 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >7 publications with SLC6A14 and Intestine
 Lung Antibodies  >3 publications with SLC6A14 and Lung
 Liver Antibodies  >2 publications with SLC6A14 and Liver
 Mammary Gland Antibodies  >2 publications with SLC6A14 and Mammary Gland
 Pancreas Antibodies  >1 publications with SLC6A14 and Pancreas
 Uterus Antibodies  >1 publications with SLC6A14 and Uterus
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