Rabbit Anti-GTF2E1 Polyclonal Antibody – Cat# MBS643654

Western Blot analysis of GTF2E1 expression in transfected 293T cell line by GTF2E1 polyclonal antibody. Lane 1: GTF2E1 transfected lysate (49.5kD). Lane 2: Non-transfected lysate.

GTF2E1 Antibody – Rabbit Polyclonal

Name: GTF2E1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS643654
Price: 970 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643654

Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. More details

$970 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GTF2E1, Polyclonal Antibody

Full Product Name

GTF2E1 (TF2E1, General Transcription Factor IIE Subunit 1, General Transcription Factor IIE 56kD Subunit, Transcription Initiation Factor IIE Subunit alpha)

Product Gene Name

anti-GTF2E1 antibody

Product Synonym Names

Anti -GTF2E1 (TF2E1, General Transcription Factor IIE Subunit 1, General Transcription Factor IIE 56kD Subunit, Transcription Initiation Factor IIE Subunit alpha)

Immunogen Sequence

MADPDVLTEV PAALKRLAKY VIRGFYGIEH ALALDILIRN SCVKEEDMLE LLKFDRKQLR SVLNNLKGDK FIKCRMRVET AADGKTTRHN YYFINYRTLV NVVKYKLDHM RRRIETDERD STNRASFKCP VCSSTFTDLE ANQLFDPMTG TFRCTFCHTE VEEDESAMPK KDARTLLARF NEQIEPIYAL LRETEDVNLA YEILEPEPTE IPALKQSKDH AATTAGAASL AGGHHREAWA TKGPSYEDLY TQNVVINMDD QEDLHRASLE GKSAKERPIW LRESTVQGAY GSEDMKEGGI DMDAFQEREE GHAGPDDNEE VMRALLIHEK KTSSAMAGSV GAAAPVTAAN GSDSESETSE SDDDSPPRPA AVAVHKREED EEEDDEFEEV ADDPIVMVAG RPFSYSEVSQ RPELVAQMTP EEKEAYIAMG QRMFEDLFE

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human GTF2E1.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

49,452 Da

Chromosome Location

Chromosome: 3; NC_000003.11 (120461558..120502216). Location: 3q21-q24

OMIM

189962

3D Structure

ModBase 3D Structure for P29083

Immunogen

Full length human GTF2E1, aa1-439 (NP_005504.2).

Product Categories/Family for anti-GTF2E1 antibody

Antibodies; Abs to Translation Initiation Factors

Applications Tested/Suitable for anti-GTF2E1 antibody

Western Blot (WB)

Application Notes for anti-GTF2E1 antibody

Suitable for use in Western Blot.

Other Notes

Small volumes of anti-GTF2E1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GTF2E1 purchase

MBS643654 is an antibody targeting GTF2E1. Also known as GTF2E1 (TF2E1, General Transcription Factor IIE Subunit 1, General Transcription Factor IIE 56kD Subunit, Transcription Initiation Factor IIE Subunit alpha). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GTF2E1. It may not necessarily be applicable to this product.

NCBI GI #

144922725

NCBI GeneID

2960

NCBI Accession #

NP_005504.2

UniProt Primary Accession #

P29083

UniProt Secondary Accession #

Q16103

UniProt Related Accession #

P29083

GenBank Nucleotide #

NM_005513.2

NCBI Official Full Name

general transcription factor IIE subunit 1

NCBI Official Synonym Full Names

general transcription factor IIE, polypeptide 1, alpha 56kDa

NCBI Official Symbol

GTF2E1

NCBI Official Synonym Symbols

FE; TF2E1; TFIIE-A

UniProt Protein Name

General transcription factor IIE subunit 1

UniProt Synonym Protein Names

General transcription factor IIE 56 kDa subunit; Transcription initiation factor IIE subunit alpha

Protein Family

General transcription factor

UniProt Gene Name

GTF2E1

UniProt Synonym Gene Names

TF2E1; TFIIE-alpha

UniProt Entry Name

T2EA_HUMAN

NCBI Protein Information

general transcription factor IIE subunit 1; TFIIE-alpha; general transcription factor IIE 56 kDa subunit; transcription initiation factor IIE subunit alpha

UniProt Comments for GTF2E1

GTF2E1: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. Belongs to the TFIIE alpha subunit family.

Protein type: Transcription initiation complex

Chromosomal Location of Human Ortholog: 3q21-q24

Cellular Component: nucleoplasm; intermediate filament cytoskeleton

Molecular Function: protein binding; sequence-specific DNA binding; metal ion binding

Biological Process: transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; regulation of transcription, DNA-dependent; viral reproduction; RNA elongation from RNA polymerase II promoter; gene expression

Research Articles on GTF2E1

1. TFIIE is an alpha/beta heterodimer in solution. A model for the quaternary architecture of the complex is proposed that provides a structural framework to discuss the function of TFIIE in the context of RNA polymerase II transcription initiation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GTF2E1 antibody

Reference Product	PubMed Publications
GTF2E2 antibody	>1 publications with GTF2E1 and GTF2E2

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