Mouse Anti-TFAP2D Polyclonal Antibody – Cat# MBS643717

Western Blot analysis of TFAP2D expression in transfected 293T cell line by TFAP2D polyclonal antibody. Lane 1: TFAP2D transfected lysate (49.72kD). Lane 2: Non-transfected lysate.

TFAP2D Antibody – Mouse Polyclonal

Name: TFAP2D Antibody; Polyclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS643717
Price: 880 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643717

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum… More details

$880 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TFAP2D, Polyclonal Antibody

Full Product Name

TFAP2D (TFAP2BL1, Transcription Factor AP-2-delta, Activating Enhancer-binding Protein 2-delta, Transcription Factor AP-2-beta-like 1)

Product Gene Name

anti-TFAP2D antibody

Product Synonym Names

Anti -TFAP2D (TFAP2BL1, Transcription Factor AP-2-delta, Activating Enhancer-binding Protein 2-delta, Transcription Factor AP-2-beta-like 1)

Immunogen Sequence

MSTTFPGLVH DAEIRHDGSN SYRLMQLGCL ESVANSTVAY SSSSPLTYST TGTEFASPYF STNHQYTPLH HQSFHYEFQH SHPAVTPDAY SLNSLHHSQQ YYQQIHHGEP TDFINLHNAR ALKSSCLDEQ RRELGCLDAY RRHDLSLMSH GSQYGMHPDQ RLLPGPSLGL AAAGADDLQG SVEAQCGLVL NGQGGVIRRG GTCVVNPTDL FCSVPGRLSL LSSTSKYKVT IAEVKRRLSP PECLNASLLG GILRRAKSKN GGRCLREKLD RLGLNLPAGR RKAANVTLLT SLVEGEALHL ARDFGYTCET EFPAKAVGEH LARQHMEQKE QTARKKMILA TKQICKEFQD LLSQDRSPLG SSRPTPILDL DIQRHLTHFS LITHGFGTPA ICAALSTFQT VLSEMLNYLE KHTTHKNGGA ADSGQGHANS EKAPLRKTSE AAVKEGKTEK TD

Clonality

Polyclonal

Isotype

IgG

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human TFAP2D.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

49,578 Da

Chromosome Location

Chromosome: 6; NC_000006.11 (50681257..50740746). Location: 6p12.1

OMIM

610161

3D Structure

ModBase 3D Structure for Q7Z6R9

Immunogen

Full length human TFAP2D, aa1-452 (NP_758438.1).

Product Categories/Family for anti-TFAP2D antibody

Antibodies; Abs to Binding Proteins

Applications Tested/Suitable for anti-TFAP2D antibody

Western Blot (WB)

Application Notes for anti-TFAP2D antibody

Suitable for use in Western Blot.

Other Notes

Small volumes of anti-TFAP2D antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TFAP2D purchase

MBS643717 is an antibody targeting TFAP2D. Also known as TFAP2D (TFAP2BL1, Transcription Factor AP-2-delta, Activating Enhancer-binding Protein 2-delta, Transcription Factor AP-2-beta-like 1). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for TFAP2D. It may not necessarily be applicable to this product.

NCBI GI #

151301211

NCBI GeneID

83741

NCBI Accession #

NP_758438.2

UniProt Primary Accession #

Q7Z6R9

UniProt Secondary Accession #

Q8IWX0

UniProt Related Accession #

Q7Z6R9

GenBank Nucleotide #

NM_172238.3

NCBI Official Full Name

transcription factor AP-2-delta

NCBI Official Synonym Full Names

transcription factor AP-2 delta (activating enhancer binding protein 2 delta)

NCBI Official Symbol

TFAP2D

NCBI Official Synonym Symbols

TFAP2BL1

UniProt Protein Name

Transcription factor AP-2-delta

UniProt Synonym Protein Names

Activating enhancer-binding protein 2-delta; Transcription factor AP-2-beta-like 1

Protein Family

Transcription factor

UniProt Gene Name

TFAP2D

UniProt Synonym Gene Names

TFAP2BL1; AP2-delta

UniProt Entry Name

AP2D_HUMAN

NCBI Protein Information

transcription factor AP-2-delta; AP-2 like; AP2-delta; transcription factor AP-2-beta-like 1; activating enhancer-binding protein 2-delta; activating enhancer binding protein 2 beta-like 1; transcription factor AP-2 beta (activating enhancer binding protein 2 beta)-like 1; transcription factor AP-2 beta (activating enhancer-binding protein 2 beta)-like 1

UniProt Comments for TFAP2D

AP-2 delta: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Belongs to the AP-2 family.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 6p12.1

Cellular Component: transcription factor complex; nucleus

Biological Process: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; anatomical structure development; positive regulation of transcription from RNA polymerase II promoter; negative regulation of neuron apoptosis; regulation of cell proliferation

Research Articles on TFAP2D

1. Taken together, these results suggest that AP-2epsilon and Ets-1 are involved in the regulation of integrin alpha10 transcription in chondrocytes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-TFAP2D antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>2 publications with TFAP2D and Brain