Pro-Brain-Derived Neurotrophic Factor Antibody – Mouse Monoclonal

BDNF is a member of the NGF family of neurotrophic factors that are required for the differentiation and survival of neuronal subpopulations in the central and peripheral nervous systems. BDNF functions through interactions with the TrkB receptor tyrosine kinase and the low affinity neurotrophin receptor, p75 (NTR). The human BDNF cDNA encodes 247aa. Cleavage of an 18aa signal sequence produces an ~35kD Pro-BDNF form. The N-terminal pro region of BDNF is removed by tPA and furin to release biologically active, 14kD BDNF. The propeptides of human and mouse BDNF share 93aa sequence identity.

Small volumes of anti-Pro-Brain-Derived Neurotrophic Factor antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS643720 is an antibody targeting Pro-Brain-Derived Neurotrophic Factor. Also known as Pro-Brain-Derived Neurotrophic Factor (Pro-BDNF). Reactive in Mouse. Host: Mouse.