• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

MAP1S Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643737

Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule-organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved… More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MAP1S, Polyclonal Antibody
Full Product Name
MAP1S, ID (MAP1S, BPY2IP1, C19orf5, MAP8, VCY2IP1, Microtubule-associated protein 1S, BPY2-interacting protein 1, Microtubule-associated protein 8, Variable charge Y chromosome 2-interacting protein 1, MAP1S heavy chain, MAP1S light chain)
Product Gene Name
anti-MAP1S antibody
Product Synonym Names
Anti -MAP1S, ID (MAP1S, BPY2IP1, C19orf5, MAP8, VCY2IP1, Microtubule-associated protein 1S, BPY2-interacting protein 1, Microtubule-associated protein 8, Variable charge Y chromosome 2-interacting protein 1, MAP1S heavy chain, MAP1S light chain)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
112,211 Da
Chromosome Location
Chromosome: 19; NC_000019.9 (17830303..17845324). Location: 19p13.11
OMIM
607573
3D Structure
ModBase 3D Structure for Q66K74
Immunogen
MAP1S antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 500-528 amino acids from the Central region of human MAP1S.

Product Categories/Family for anti-MAP1S antibody

Antibodies; Abs to KIAA; orf
Applications Tested/Suitable for anti-MAP1S antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes for anti-MAP1S antibody
Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Flow Cytometry: 1:10-50

Western Blot (WB) of anti-MAP1S antibody

MAP1S Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MAP1S antibody detected the MAP1S protein (arrow).
Rabbit Anti-MAP1S Polyclonal Antibody – Cat# MBS643737

Immunohistochemistry (IHC) of anti-MAP1S antibody

MAP1S Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MAP1S Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-MAP1S Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS643737

Flow Cytometry (FC/FACS) of anti-MAP1S antibody

MAP1S Antibody (Center) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-MAP1S Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS643737

Other Notes

Small volumes of anti-MAP1S antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MAP1S purchase

MBS643737 is an antibody targeting MAP1S. Also known as MAP1S, ID (MAP1S, BPY2IP1, C19orf5, MAP8, VCY2IP1, Microtubule-associated protein 1S, BPY2-interacting protein 1, Microtubule-associated protein 8, Variable charge Y chromosome 2-interacting protein 1, MAP1S heavy chain, MAP1S light chain). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MAP1S. It may not necessarily be applicable to this product.

NCBI GI #
50428935
NCBI GeneID
55201
NCBI Accession #
NP_060644.4
UniProt Primary Accession #
Q66K74
UniProt Secondary Accession #
Q27QB1; Q6NXF1; Q8N3L8; Q8N3W5; Q8NI88; Q96H94; Q96IT4; Q96SP8; Q9BRC6; Q9H928; Q9NVK7
UniProt Related Accession #
Q66K74
GenBank Nucleotide #
NM_018174.4
NCBI Official Full Name
microtubule-associated protein 1S
NCBI Official Synonym Full Names
microtubule-associated protein 1S
NCBI Official Symbol
MAP1S
NCBI Official Synonym Symbols
MAP8; BPY2IP1; C19orf5; VCY2IP1; VCY2IP-1
UniProt Protein Name
Microtubule-associated protein 1S
UniProt Synonym Protein Names
BPY2-interacting protein 1; Microtubule-associated protein 8; Variable charge Y chromosome 2-interacting protein 1
Protein Family
Microtubule-associated protein
UniProt Gene Name
MAP1S
UniProt Synonym Gene Names
BPY2IP1; C19orf5; MAP8; VCY2IP1; MAP-1S; VCY2-interacting protein 1; VCY2IP-1
UniProt Entry Name
MAP1S_HUMAN
NCBI Protein Information
microtubule-associated protein 1S; MAP-1S; BPY2 interacting protein 1; BPY2-interacting protein 1; VCY2 interacting protein 1; VCY2-interacting protein 1; microtubule-associated protein 8; variable charge Y chromosome 2-interacting protein 1

UniProt Comments for MAP1S

BPY2-IP1: Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule-organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles. Belongs to the MAP1 family.

Protein type: Apoptosis; Microtubule-binding

Chromosomal Location of Human Ortholog: 19p13.11

Cellular Component: microtubule; cell projection; cell soma; perinuclear region of cytoplasm; cytoplasm; dendrite; nucleolus; spindle; synapse; nucleus; cell junction; cytosol

Molecular Function: tubulin binding; actin filament binding; identical protein binding; protein binding; DNA binding; microtubule binding; beta-tubulin binding; deoxyribonuclease activity

Biological Process: nervous system development; DNA fragmentation during apoptosis; brain development; microtubule bundle formation; neurite morphogenesis; mitochondrion transport along microtubule
Show more

Research Articles on MAP1S

1. clarify roles of MAP1S in bridging microtubules and mitochondria with autophagic and mitophagic initiation, maturation, trafficking, and lysosomal clearance.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-MAP1S antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >4 publications with MAP1S and Neoplasms
 Cell Transformation, Neoplastic Antibodies  >2 publications with MAP1S and Cell Transformation, Neoplastic
 Cardiovascular Diseases Antibodies  >1 publications with MAP1S and Cardiovascular Diseases
 Aneuploidy Antibodies  >1 publications with MAP1S and Aneuploidy
 Breast Neoplasms Antibodies  >1 publications with MAP1S and Breast Neoplasms
 Lymphoma Antibodies  >1 publications with MAP1S and Lymphoma
 Liver Neoplasms Antibodies  >1 publications with MAP1S and Liver Neoplasms
 Liver Diseases Antibodies  >1 publications with MAP1S and Liver Diseases

Organs/Tissues associated with anti-MAP1S antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >5 publications with MAP1S and Nerve
 Brain Antibodies  >5 publications with MAP1S and Brain
 Liver Antibodies  >2 publications with MAP1S and Liver
 Blood Antibodies  >1 publications with MAP1S and Blood
 Bone Antibodies  >1 publications with MAP1S and Bone
 Muscle Antibodies  >1 publications with MAP1S and Muscle
 Uterus Antibodies  >1 publications with MAP1S and Uterus
 Embryonic Tissue Antibodies  >1 publications with MAP1S and Embryonic Tissue
 Lung Antibodies  >1 publications with MAP1S and Lung
 Stomach Antibodies  >1 publications with MAP1S and Stomach
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000