Rabbit Anti-TREM1 Polyclonal Antibody – Cat# MBS643771

TREM1 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the TREM1 antibody detected the TREM1 protein (arrow).

TREM1 Antibody – Rabbit Polyclonal

Name: TREM1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS643771
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643771

Monocyte/macrophage- and neutrophil-mediated inflammatory responses can be stimulated through a variety of receptors, including G protein-linked 7-transmembrane receptors (e.g., FPR1; MIM 136537), Fc receptors (see MIM 146790), CD14 (MIM 158120) and Toll-like… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TREM1, Polyclonal Antibody

Full Product Name

TREM1, CT (TREM1, Triggering receptor expressed on myeloid cells 1, Triggering receptor expressed on monocytes 1, CD354)

Product Gene Name

anti-TREM1 antibody

Product Synonym Names

Anti -TREM1, CT (TREM1, Triggering receptor expressed on myeloid cells 1, Triggering receptor expressed on monocytes 1, CD354)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

26,387 Da

Chromosome Location

Chromosome: 6; NC_000006.11 (41242999..41254457, complement). Location: 6p21.1

OMIM

605085

3D Structure

ModBase 3D Structure for Q9NP99

Immunogen

TREM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic between 161-191 amino acids selected from the C-terminal region of human TREM1.

Product Categories/Family for anti-TREM1 antibody

Antibodies; Abs to CD Markers

Applications Tested/Suitable for anti-TREM1 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-TREM1 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-TREM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TREM1 purchase

MBS643771 is an antibody targeting TREM1. Also known as TREM1, CT (TREM1, Triggering receptor expressed on myeloid cells 1, Triggering receptor expressed on monocytes 1, CD354). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TREM1. It may not necessarily be applicable to this product.

NCBI GI #

336088680

NCBI GeneID

54210

NCBI Accession #

NP_001229518.1

UniProt Primary Accession #

Q9NP99

UniProt Secondary Accession #

Q53FL8; Q5T2C9; Q86YU1; B4DWG2

UniProt Related Accession #

Q9NP99

GenBank Nucleotide #

NM_001242589.1

NCBI Official Full Name

triggering receptor expressed on myeloid cells 1 isoform 2

NCBI Official Synonym Full Names

triggering receptor expressed on myeloid cells 1

NCBI Official Symbol

TREM1

NCBI Official Synonym Symbols

CD354; TREM-1

UniProt Protein Name

Triggering receptor expressed on myeloid cells 1

UniProt Synonym Protein Names

Triggering receptor expressed on monocytes 1

Protein Family

Triggering receptor expressed on myeloid cells

UniProt Gene Name

TREM1

UniProt Synonym Gene Names

TREM-1

UniProt Entry Name

TREM1_HUMAN

NCBI Protein Information

triggering receptor expressed on myeloid cells 1; triggering-receptor TREM1; triggering receptor expressed on monocytes 1

NCBI Summary for TREM1

This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]

UniProt Comments for TREM1

TREM1: Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 6p21.1

Cellular Component: plasma membrane; integral to membrane; extracellular region

Molecular Function: receptor activity

Biological Process: neutrophil chemotaxis; innate immune response; cytokine secretion during immune response; blood coagulation; chemokine metabolic process; leukocyte migration; humoral immune response

Research Articles on TREM1

1. sTREM-1 concentrations in maternal serum were elevated during spontaneous term and preterm labor and sTREM-1 levels were significantly higher in preterm labor.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TREM1 antibody

Reference Product	PubMed Publications
TYROBP antibody	>22 publications with TREM1 and TYROBP
TLR4 antibody	>13 publications with TREM1 and TLR4
TLR2 antibody	>8 publications with TREM1 and TLR2
CLEC5A antibody	>2 publications with TREM1 and CLEC5A
TREML2 antibody	>2 publications with TREM1 and TREML2
FPR1 antibody	>1 publications with TREM1 and FPR1

Pathways associated with anti-TREM1 antibody

Products by Pathway	Pathway Diagram
Cell Surface Interactions At The Vascular Wall Pathway antibodies	Cell Surface Interactions At The Vascular Wall Pathway Diagram
DAP12 Interactions Pathway antibodies	DAP12 Interactions Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram

Diseases associated with anti-TREM1 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>171 publications with TREM1 and Inflammation
Lung Diseases Antibodies	>67 publications with TREM1 and Lung Diseases
Pneumonia Antibodies	>60 publications with TREM1 and Pneumonia
Respiratory Tract Infections Antibodies	>55 publications with TREM1 and Respiratory Tract Infections
Necrosis Antibodies	>53 publications with TREM1 and Necrosis
Neoplasms Antibodies	>21 publications with TREM1 and Neoplasms
Cardiovascular Diseases Antibodies	>14 publications with TREM1 and Cardiovascular Diseases
Disease Models, Animal Antibodies	>11 publications with TREM1 and Disease Models, Animal
Skin Diseases Antibodies	>9 publications with TREM1 and Skin Diseases
Kidney Diseases Antibodies	>5 publications with TREM1 and Kidney Diseases

Organs/Tissues associated with anti-TREM1 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>187 publications with TREM1 and Blood
Lung Antibodies	>38 publications with TREM1 and Lung
Bone Antibodies	>20 publications with TREM1 and Bone
Intestine Antibodies	>13 publications with TREM1 and Intestine
Brain Antibodies	>12 publications with TREM1 and Brain
Bone Marrow Antibodies	>8 publications with TREM1 and Bone Marrow
Connective Tissue Antibodies	>3 publications with TREM1 and Connective Tissue
Spleen Antibodies	>2 publications with TREM1 and Spleen
Pharynx Antibodies	>2 publications with TREM1 and Pharynx
Placenta Antibodies	>2 publications with TREM1 and Placenta