Rabbit Anti-HIST1H2AA Polyclonal Antibody – Cat# MBS643777

HIST1H2AA Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the HIST1H2AA antibody detected the HIST1H2AA protein (arrow).

HIST1H2AA Antibody – Rabbit Polyclonal

Name: HIST1H2AA Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS643777
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643777

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

HIST1H2AA, Polyclonal Antibody

Full Product Name

HIST1H2AA, NT (HIST1H2AA, H2AFR, Histone H2A type 1-A, Histone H2A/r)

Product Gene Name

anti-HIST1H2AA antibody

Product Synonym Names

Anti -HIST1H2AA, NT (HIST1H2AA, H2AFR, Histone H2A type 1-A, Histone H2A/r)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

14,234 Da

Chromosome Location

Chromosome: 6; NC_000006.11 (25726291..25726790, complement). Location: 6p22.2

OMIM

613499

3D Structure

ModBase 3D Structure for Q96QV6

Immunogen

HIST1H2AA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HIST1H2AA.

Product Categories/Family for anti-HIST1H2AA antibody

Antibodies; Abs to Histones

Applications Tested/Suitable for anti-HIST1H2AA antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-HIST1H2AA antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-HIST1H2AA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HIST1H2AA purchase

MBS643777 is an antibody targeting HIST1H2AA. Also known as HIST1H2AA, NT (HIST1H2AA, H2AFR, Histone H2A type 1-A, Histone H2A/r). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HIST1H2AA. It may not necessarily be applicable to this product.

NCBI GI #

25092737

NCBI GeneID

221613

NCBI Accession #

NP_734466.1

UniProt Primary Accession #

Q96QV6

UniProt Related Accession #

Q96QV6

GenBank Nucleotide #

NM_170745.3

NCBI Official Full Name

histone H2A type 1-A

NCBI Official Synonym Full Names

histone cluster 1, H2aa

NCBI Official Symbol

HIST1H2AA

NCBI Official Synonym Symbols

H2AA; H2AFR; bA317E16.2

UniProt Protein Name

Histone H2A type 1-A

UniProt Synonym Protein Names

Histone H2A/r

Protein Family

Histone

UniProt Gene Name

HIST1H2AA

UniProt Synonym Gene Names

H2AFR

UniProt Entry Name

H2A1A_HUMAN

NCBI Protein Information

histone H2A type 1-A; histone H2A/r; histone 1, H2aa; H2A histone family, member R

UniProt Comments for HIST1H2AA

H2A.4: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. Belongs to the histone H2A family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 6p22.2

Cellular Component: nucleosome; nucleus

Molecular Function: DNA binding; protein heterodimerization activity

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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