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B3GNT1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643829

This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It is essential for the synthesis of poly-N-acetyllactosamine, a determinant for the blood group i antigen. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
B3GNT1, Polyclonal Antibody
Full Product Name
B3GNT1, CT (B3GNT1, B3GNT6, N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase, I-beta-1,3-N-acetylglucosaminyltransferase, Poly-N-acetyllactosamine extension enzyme, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1)
Product Gene Name
anti-B3gnt1 antibody
Product Synonym Names
Anti -B3GNT1, CT (B3GNT1, B3GNT6, N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase, I-beta-1,3-N-acetylglucosaminyltransferase, Poly-N-acetyllactosamine extension enzyme, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
47,384 Da
Chromosome Location
Chromosome: 19; NC_000085.6 (5038826..5041134). Location: 19 A; 19
3D Structure
ModBase 3D Structure for Q8BWP8
Immunogen
B3GNT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 365-394 amino acids from the C-terminal region of human B3GNT1.

Product Categories/Family for anti-B3gnt1 antibody

Antibodies; Abs to Enzymes; Glycosyltransferase
Applications Tested/Suitable for anti-B3gnt1 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-B3gnt1 antibody
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50

Western Blot (WB) of anti-B3gnt1 antibody

B3GNT1 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the B3GNT1 antibody detected the B3GNT1 protein (arrow).
Rabbit Anti-B3GNT1 Polyclonal Antibody – Cat# MBS643829

Immunohistochemistry (IHC) of anti-B3gnt1 antibody

B3GNT1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of B3GNT1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-B3GNT1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS643829

Other Notes

Small volumes of anti-B3gnt1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for B3gnt1 purchase

MBS643829 is an antibody targeting B3gnt1. Also known as B3GNT1, CT (B3GNT1, B3GNT6, N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase, I-beta-1,3-N-acetylglucosaminyltransferase, Poly-N-acetyllactosamine extension enzyme, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for B3gnt1. It may not necessarily be applicable to this product.

NCBI GI #
47124409
NCBI GeneID
108902
NCBI Accession #
AAH69927.1
UniProt Primary Accession #
Q8BWP8
UniProt Secondary Accession #
Q3TY43; Q8BJH9; Q99LW7
UniProt Related Accession #
Q8BWP8
NCBI Official Full Name
B3gnt1 protein
NCBI Official Synonym Full Names
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
NCBI Official Symbol
B3gnt1
NCBI Official Synonym Symbols
iGAT; iGNT; B3gnt6; BETA3GNT1; 1500032M01Rik
UniProt Protein Name
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase
UniProt Synonym Protein Names
I-beta-1,3-N-acetylglucosaminyltransferase; iGnT; Poly-N-acetyllactosamine extension enzyme; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
UniProt Gene Name
B3gnt1
UniProt Synonym Gene Names
B3gnt6; iGnT
UniProt Entry Name
B3GN1_MOUSE
NCBI Protein Information
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase; poly-N-acetyllactosamine extension enzyme; I-beta-1,3-N-acetylglucosaminyltransferase; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6

UniProt Comments for B3gnt1

B4GAT1: Can initiate the synthesis or the elongation of the linear poly-N-acetyllactosaminoglycans.

Protein type: Glycan Metabolism - keratan sulfate biosynthesis; Membrane protein, integral; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; EC 2.4.1.149; Transferase

Cellular Component: Golgi apparatus; membrane; integral to membrane

Molecular Function: glucuronosyltransferase activity; metal ion binding; alpha(1,6)-fucosyltransferase activity; oligosaccharyl transferase activity; acetylgalactosaminyltransferase activity; alpha(1,3)-fucosyltransferase activity; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity; glucosyltransferase activity; O antigen polymerase activity; alpha-1,2-mannosyltransferase activity; acetylglucosaminyltransferase activity; transferase activity, transferring glycosyl groups; 1-phenanthrol glycosyltransferase activity; phenanthrol glycosyltransferase activity; glycolipid mannosyltransferase activity; galactosyltransferase activity; dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity; dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity; fucosyltransferase activity; lipopolysaccharide-1,6-galactosyltransferase activity; alpha-1,3-galactosyltransferase activity; alpha-1,2-galactosyltransferase activity; 9-phenanthrol UDP-glucuronosyltransferase activity; dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity; UDP-glucose:glycoprotein glucosyltransferase activity; 1,2-dihydroxy-phenanthrene glycosyltransferase activity; 9-phenanthrol glycosyltransferase activity; transferase activity; dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity; beta-1,4-mannosyltransferase activity; cellulose synthase activity; mannosyltransferase activity; alpha-1,3-mannosyltransferase activity; alpha-1,6-mannosyltransferase activity; inositol phosphoceramide synthase activity

Biological Process: axon guidance; protein amino acid O-linked mannosylation; protein amino acid glycosylation
Show more

Research Articles on B3gnt1

1. This study demonistrated that the axonal guidance defects observed in B3gnt1 mutant mice

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-B3gnt1 antibody

 Reference Product  PubMed Publications
 Fut9 antibody  >1 publications with B3gnt1 and Fut9

Pathways associated with anti-B3gnt1 antibody

 Products by Pathway  Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Glycosaminoglycan Biosynthesis - Keratan Sulfate Pathway antibodies  Glycosaminoglycan Biosynthesis - Keratan Sulfate Pathway Diagram
 Glycosaminoglycan Biosynthesis - Keratan Sulfate Pathway antibodies  Glycosaminoglycan Biosynthesis - Keratan Sulfate Pathway Diagram
 Glycosaminoglycan Metabolism Pathway antibodies  Glycosaminoglycan Metabolism Pathway Diagram
 Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway antibodies  Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway Diagram
 Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway antibodies  Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway Diagram
 Keratan Sulfate Biosynthesis Pathway antibodies  Keratan Sulfate Biosynthesis Pathway Diagram
 Keratan Sulfate/keratin Metabolism Pathway antibodies  Keratan Sulfate/keratin Metabolism Pathway Diagram
 MPS I - Hurler Syndrome Pathway antibodies  MPS I - Hurler Syndrome Pathway Diagram
 MPS II - Hunter Syndrome Pathway antibodies  MPS II - Hunter Syndrome Pathway Diagram

Diseases associated with anti-B3gnt1 antibody

 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >1 publications with B3gnt1 and Congenital Abnormalities

Organs/Tissues associated with anti-B3gnt1 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with B3gnt1 and Brain
 Eye Antibodies  >1 publications with B3gnt1 and Eye
 Testis Antibodies  >1 publications with B3gnt1 and Testis
 Kidney Antibodies  >1 publications with B3gnt1 and Kidney
 Embryonic Tissue Antibodies  >1 publications with B3gnt1 and Embryonic Tissue
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