Rabbit Anti-ciapin1 Polyclonal Antibody – Cat# MBS643937

CIAPIN1 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CIAPIN1 antibody detected the CIAPIN1 protein (arrow).

ciapin1 Antibody – Rabbit Polyclonal

Name: ciapin1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS643937
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643937

CIAPIN1 is a cytokine-induced inhibitor of apoptosis with no relation to apoptosis regulatory molecules of the BCL2 (MIM 151430) or CASP (see MIM 147678) families. Expression of CIAPIN1 is dependent on growth factor stimulation (Shibayama et al., 2004 [PubMed… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CIAPIN1, Polyclonal Antibody

Full Product Name

CIAPIN1, ID (CIAPIN1, Anamorsin, Cytokine-induced apoptosis inhibitor 1, Fe-S cluster assembly protein DRE2 homolog)

Product Gene Name

anti-ciapin1 antibody

Product Synonym Names

Anti -CIAPIN1, ID (CIAPIN1, Anamorsin, Cytokine-induced apoptosis inhibitor 1, Fe-S cluster assembly protein DRE2 homolog)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

32,902 Da

Chromosome Location

Chromosome: 25; NC_007136.5 (14659318..14667405). Location: chromosome: 25

3D Structure

ModBase 3D Structure for Q6AZB3

Immunogen

CIAPIN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-108 amino acids from the Central region of human CIAPIN1.

Product Categories/Family for anti-ciapin1 antibody

Antibodies; Abs to Apoptosis

Applications Tested/Suitable for anti-ciapin1 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-ciapin1 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-ciapin1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ciapin1 purchase

MBS643937 is an antibody targeting ciapin1. Also known as CIAPIN1, ID (CIAPIN1, Anamorsin, Cytokine-induced apoptosis inhibitor 1, Fe-S cluster assembly protein DRE2 homolog). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ciapin1. It may not necessarily be applicable to this product.

NCBI GI #

182891208

NCBI GeneID

445283

NCBI Accession #

AAI64092.1

UniProt Primary Accession #

Q6AZB3

UniProt Secondary Accession #

A2AV35

UniProt Related Accession #

Q6AZB3

NCBI Official Full Name

Ciapin1 protein

NCBI Official Synonym Full Names

cytokine induced apoptosis inhibitor 1

NCBI Official Symbol

ciapin1

NCBI Official Synonym Symbols

zgc:92009; wu:fc46b12

UniProt Protein Name

Anamorsin

UniProt Synonym Protein Names

Cytokine-induced apoptosis inhibitor 1; Fe-S cluster assembly protein DRE2 homolog

Protein Family

Anamorsin

UniProt Gene Name

ciapin1

UniProt Entry Name

CPIN1_DANRE

NCBI Protein Information

anamorsin; fc46b12; cytokine-induced apoptosis inhibitor 1; fe-S cluster assembly protein DRE2 homolog

UniProt Comments for ciapin1

Function: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Electrons are transferred to the Fe-S cluster from NADPH via the FAD- and FMN-containing protein ndor1

By similarity. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells

By similarity. HAMAP-Rule MF_03115

Cofactor: Binds 1 2Fe-2S cluster per subunit

By similarity. HAMAP-Rule MF_03115

Subunit structure: Monomer

By similarity. Interacts with ndor1

By similarity. Interacts with chchd4

By similarity. HAMAP-Rule MF_03115

Subcellular location: Cytoplasm

By similarity. Nucleus

By similarity. Mitochondrion intermembrane space

By similarity HAMAP-Rule MF_03115.

Domain: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine

By similarity. HAMAP-Rule MF_03115The C-terminal domain binds one 2Fe-2S iron-sulfur cluster but is otherwise mostly in an intrinsically disordered conformation

By similarity. HAMAP-Rule MF_03115The twin Cx2C motifs are involved in the recognition by the mitochondrial CHCHD4/MIA40-GFER/ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space

By similarity. HAMAP-Rule MF_03115

Sequence similarities: Belongs to the anamorsin family.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ciapin1 antibody

Products by Pathway	Pathway Diagram
Cytosolic Iron-sulfur Cluster Assembly Pathway antibodies	Cytosolic Iron-sulfur Cluster Assembly Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram

Diseases associated with anti-ciapin1 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>21 publications with ciapin1 and Neoplasms
Adenocarcinoma Antibodies	>5 publications with ciapin1 and Adenocarcinoma
Liver Neoplasms Antibodies	>2 publications with ciapin1 and Liver Neoplasms
Pancreatic Neoplasms Antibodies	>1 publications with ciapin1 and Pancreatic Neoplasms
Breast Neoplasms Antibodies	>1 publications with ciapin1 and Breast Neoplasms
Ovarian Neoplasms Antibodies	>1 publications with ciapin1 and Ovarian Neoplasms
Nerve Degeneration Antibodies	>1 publications with ciapin1 and Nerve Degeneration
Liver Diseases Antibodies	>1 publications with ciapin1 and Liver Diseases
Skin Diseases Antibodies	>1 publications with ciapin1 and Skin Diseases
Disease Models, Animal Antibodies	>1 publications with ciapin1 and Disease Models, Animal

Organs/Tissues associated with anti-ciapin1 antibody

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>1 publications with ciapin1 and Muscle
Brain Antibodies	>1 publications with ciapin1 and Brain